Alien Registration- Von Koschembahr, Gundula (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_docs/23578/thumbnail.jp

Designing a typeface

The purpose of this project was to design a typeface, using digital methods,and in so doing to explore the use of current type design software. In this project, letterforms that were originally produced by hand with a pen were translated into electronic data, taking the final form of a digital typeface. Photographic images of manuscript letterforms were enlarged; from the enlarged letterforms hand-rendered outlines were created. These outlines were scanned electronically and imported into a type design software program. Digital outlines of each character were created, from which a PostScript typeface was generated and printed. The result of the project is a digitally produced and generated PostScript typeface, which can be output at any size or resolution. Although the typeface was generated with a machine, it nonetheless maintains the character of hand-rendered calligraphic letterforms, as can be seen when comparing the type to its original historical source

Paracrine Regulation of Melanocyte Genomic Stability: A Focus on Nucleotide Excision Repair

UV radiation is a major environmental risk factor for the development of melanoma by causing DNA damage and mutations. Resistance to UV damage is largely determined by the capacity of melanocytes to respond to UV injury by repairing mutagenic photolesions. The nucleotide excision repair (NER) pathway is the major mechanism by which cells correct UV photodamage. This multistep process involves the basic steps of damage recognition, isolation, localized strand unwinding, assembly of a repair complex, excision of the damage‐containing strand 3′ and 5′ to the photolesion, synthesis of a sequence‐appropriate replacement strand, and finally ligation to restore continuity of genomic DNA. In melanocytes, the efficiency of NER is regulated by several hormonal pathways including the melanocortin and endothelin signaling pathways. Elucidating molecular mechanisms by which melanocyte DNA repair is regulated offers the possibility of developing novel melanoma‐preventive strategies to reduce UV mutagenesis, especially in UV‐sensitive melanoma‐prone individuals

Alien Registration Card- Von Koschembahr, Gerhard (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_cards/1125/thumbnail.jp

Alien Registration- Von Koschembahr, Gerhard (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_docs/23574/thumbnail.jp

Alien Registration- Von Koschembahr, Gerhard (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_docs/23575/thumbnail.jp

Alien Registration- Von Koschembahr, Margarete (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_docs/23577/thumbnail.jp

Alien Registration Card- Von Koschembahr, Gundula (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_cards/1126/thumbnail.jp

Alien Registration- Von Koschembahr, Gundula (Cape Elizabeth, Cumberland County)

https://digitalmaine.com/alien_docs/23578/thumbnail.jp