Possibilidade jurídica do estupro virtual de vulnerável

O presente trabalho objetiva analisar a possibilidade jurídica do estupro virtual de vulnerável diante das alterações advindas da Lei n° 12.015/2009. Concomitantemente, analisa os elementos do tipo, quais sejam, o ato libidinoso, a necessidade de contato, as peculiaridades do vulnerável. Além disso, são feitas considerações a respeito do ambiente virtual, meio utilizado pelo agressor chegar até a vítima. São analisadas as dificuldades teóricas e principiológicas do reconhecimento do tipo penal e as formas de enfretamento encontradas. Por fim, observa as perspectivas legislativas quanto ao tema. Com base nos ensinamentos da doutrina e jurisprudência, conclui que a viabilidade da tipificação penal se dá por meio da interpretação extensiva do termo “ato libidinoso” disposto no artigo 217-A do Código Penal.This paper aims to analyze the legal possibility of virtual rape of the vulnerable considering the changes that came from Law n°12.015/2009. Concomitantly, it analyze the elements of the felony, namely, the libidinous act, the need for contact, the vulnerable’s peculiarities and the crime victim. Further, considerations are made regarding the virtual environment, the way used by the aggressor to reach the victim. The theoretical and principiological difficulties of recognizing the penal classification are analyzed as well as the forms of facing them. Finally, it remarks the legislative perspectives on the topic. Based on the teachings of doctrine and precedents, it concludes that the feasibility of criminal classification occurs through the extensive interpretation of the term “libidinous act” fixed in the article 217-A of the Criminal Code

Evaluation of Short-term Psychoanalytic Child Therapy (PaCT) for Young Children with Depressive Disorders: Results from a Pilot Study

Depressive disorders in early childhood are associated with high psychosocial impairment and tend to remain stable over time without adequate treatment. Short-term psychoanalytic therapy is a common form of child psychotherapy, yet there is a lack of empirical evaluation of this approach for young children with depressive disorders. Therefore, this secondary evaluation of a study on the treatment of anxiety disorders used an uncontrolled pre-post design in a clinical setting to investigate whether children with depressive comorbidity would evidence significant diagnostic and symptomatic remission after treatment with manualized short-term Psychoanalytic Child Therapy (PaCT). Nineteen children who had an anxiety disorder and a (subclinical) depressive disorder (assessed with the Preschool Age Psychiatric Assessment using DSM-IV criteria) were treated with PaCT. After treatment, 15 of 19 children (78.94 %) were remitted and 15 of 17 children (88.24 %; 2 were lost to follow-up) were free of depressive disorders at the 6-month follow-up. Further analyses revealed significant effects for pre- to post and pre- to follow-up comparisons regarding internalizing symptoms and overall problems using parent- and (nursery-)teacher-ratings. These results suggest that short-term PaCT shows promise as a treatment for childhood depressive disorders

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system

Conditional expression systems are of pivotal importance for the dissection of complex biological phenomena. Here, we describe a novel EBV-derived episomally replicating plasmid (pRTS-1) that carries all the elements for conditional expression of a gene of interest via Tet regulation. The vector is characterized by (i) low background activity, (ii) high inducibility in the presence of doxycycline (Dox) and (iii) graded response to increasing concentrations of the inducer. The chicken beta actin promoter and an element of the murine immunoglobin heavy chain intron enhancer drive constitutive expression of a bicistronic expression cassette that encodes the highly Dox-sensitive reverse tetracycline controlled transactivator rtTA2(S)-M2 and a Tet repressor-KRAB fusion protein (tTS(KRAB)) (silencer) placed downstream of an internal ribosomal entry site. The gene of interest is expressed from the bidirectional promoter P(tet)bi-1 that allows simultaneous expression of two genes, of which one may be used as surrogate marker for the expression of the gene of interest. Tight down regulation is achieved through binding of the silencer tTS(KRAB) to P(tet)bi-1 in the absence of Dox. Addition of Dox releases repression and via binding of rtTA2(S)-M2 activates P(tet)bi-1

Pro-Inflammatory S100A8 and S100A9 Proteins: Self-Assembly into Multifunctional Native and Amyloid Complexes

S100A8 and S100A9 are EF-hand Ca2+ binding proteins belonging to the S100 family. They are abundant in cytosol of phagocytes and play critical roles in numerous cellular processes such as motility and danger signaling by interacting and modulating the activity of target proteins. S100A8 and S100A9 expression levels increased in many types of cancer, neurodegenerative disorders, inflammatory and autoimmune diseases and they are implicated in the numerous disease pathologies. The Ca2+ and Zn2+-binding properties of S100A8/A9 have a pivotal influence on their conformation and oligomerization state, including self-assembly into homo- and heterodimers, tetramers and larger oligomers. Here we review how the unique chemical and conformational properties of individual proteins and their structural plasticity at the quaternary level account for S100A8/A9 functional diversity. Additional functional diversification occurs via non-covalent assembly into oligomeric and fibrillar amyloid complexes discovered in the aging prostate and reproduced in vitro. This process is also regulated by Ca2+and Zn2+-binding and effectively competes with the formation of the native complexes. High intrinsic amyloid-forming capacity of S100A8/A9 proteins may lead to their amyloid depositions in numerous ailments characterized by their elevated expression patterns and have additional pathological significance requiring further thorough investigation

Arranging Orchestral Music for the Pope of Instruments: An Applied Analysis of Arrangements by Beethoven, Lemare and Liszt

Note:Arrangements for keyboard instruments played a significant role in the musical life of the nineteenth and early twentieth centuries. Based on an analysis of writings and arrangements by Ludwig van Beethoven (i.e., the composer arranging his own works), Edwin H. Lemare (i.e., a prolific arranger for the organ) and Franz Liszt (i.e., a prolific arranger for the piano), this paper discusses their respective reasons for arranging and their techniques of arrangement. (...) The author has applied the results of his research in his own arrangement for organ of the Second Movement from Ludwig van Beethoven’s Fifth Symphony. Excerpts from this arrangement are presented after each analytical section, together with an explanation of the decision-making process during the making of the arrangement.This paper concludes with an evaluation of the benefits of arrangements for the organ in today’s music scene.Les transcriptions ont joué un rôle majeur dans la vie musicale du dix-neuvième siècle et au début du vingtième siècle. Fondée sur une analyse des écrits et des transcriptions de Ludwig van Beethoven (un compositeur qui a transcrit ses propres oeuvres), Edwin H. Lemare (un arrangeur fécond pour l’orgue) et Franz Liszt (un arrangeur fécond pour le piano), cette thèse doctorale discute des raisons en faveur des transcriptions et la technique de ces trois compositeurs/arrangeurs. (...) L’auteur de cette thèse a appliqué les résultats de ses recherches à sa propre transcription du Deuxième Mouvement de la Cinquième Symphonie de Ludwig van Beethoven pour orgue. Des extraits de cette transcription sont présentés après chaque section analytique, avec des explications concernant les décisions prises pendant la rédaction de la transcription.La thèse se termine par une évaluation des avantages des transcriptions destinées à l’orgue dans la vie musicale d’aujourd’hui

Sustainable development: a case study of the natural resource use of Yelwa Village, Nigeria

The world today faces many challenges. Reducing poverty and protecting the environment are prominent amongst these challenges, and consequently both are high on priority lists for many national, international, governmental and non-governmental organizations. Since the 1980s there has been an increasing awareness that environmental protection must not fly in the face of social justice, especially in developing countries, and that a system can only truly achieve sustainability if it is socially just and economically sound, as well as environmentally secure. Likewise poverty reduction at the cost of the environment is worthless in the long term. This has given rise to much more holistic approaches to both conservation and poverty reduction policies and brought the rights of communities living in or near protected areas into the international focus. However, wether it is possible to conserve biodiversity and protect habitats successfully without undermining the livelihoods of local communities, or wether it is possible to offer development aid to an impoverished region without jeopardizing their local environment, is a question which has not been resolved. This study approaches this debate by examining the relationship between the livelihoods and natural resources of a rural village adjacent to a forest reserve on the Mambilla Highlands in Nigeria. A mixture of qualitative and quantitative techniques were employed during five months spent living on location to develop a picture of the situation as it currently exists, the environmental effects of development in the village to date, and the effects of these environmental changes on people’s livelihoods. Based on this research this thesis concludes that development in a region certainly increases the vulnerability of the environment. However, rather than concluding that this makes development and environmental protection conflicting agendas, this thesis argues that this period of vulnerability presents opportunities to develop true sustainability, as effective sustainable practices can develop from the experience of resource depletion. Additionally, examples of how knowledge sharing and dialogue between western scientists and indigenous communities has the potential to facilitate and accelerate this process are discussed

The link between interest rates on interbank money and for credit lines: are asymmetric interest rate adjustments empirically evident?

Summary in GermanAvailable from Bibliothek des Instituts fuer Weltwirtschaft, ZBW, Duesternbrook Weg 120, D-24105 Kiel W 179 (97.37) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman