Loading and securing cargo on heavy vehicles

Cilj naloge, ki je pred vami, je tako na tehničnen kot tudi praktičnen način predstaviti pritrjevanje tovora v cestnem prometu. Uvod je namenjen predstavitvi trenutnega stanja v slovenskem prostoru in primerjava le tega s prakso v Nemčiji. Sledi fizikalno teoretični del naloge, ki je močno podkrepljen s teoretičnimi razlagami ter praktičnimi primeri, zaradi česar postane razumevanje obravnavane teme lažje. V naslednjem poglavju sem obravnaval sile, ki med prevozom delujejo na tovor, ter posledično definiral potrebe po pritrjevanju blaga za posamezno vrsto transporta. Pri določanju razporeditve tovora sem predstavil njegov pomen ter analitično in grafično metodo za določanje težišča. Podrobneje sem predstavil tudi posamezne vrste tovornih nadgradenj, mest za pritrjevanje in sredstev za pritrjevanje ter navedel njihove značilnosti in primernosti za pritrjevanje različnih vrst tovora. V poglavju Načini pritrjevanja tovora sem razdelal metode pritrjevanja, za posamezne sem podal tudi praktične računske primere. V zadnjem delu naloge sem predstavil tudi pritrjevanje posebnih vrst tovorov in podal napotke za pritrjevanje tovora v osebnih in kombiniranih vozilih ter zaključil s komentarjem in predstavitvijo rezultatov izvedene ankete.In this master thesis I have in greater provision studied both theoretical and practical part of securing loads on road vehicles. In introduction I have presented the situation in Slovenia and compared it with Germany where they have a lot of practical experiences and existing legal requirements for cargo securing. In the first chapter I have tried to present the topic, giving many practical examples of cargo transport, which were explained with physical and theoretical bases. In the following chapter I have introduced both arithmetic and graphic method to define centre of gravity and other forces and explain how they act on axle load distribution. Different types of transport vehicles and their demands for cargo securing, types of anchorage points and different types of load securing equipment are introduced in the next chapter. I have also introduced different types of cargo securing methods and gave some practical examples for each method. Last part of this thesis deals with transport and securing specific loads and loads in personal vehicles and vans. At the end I have introduced results of cargo securing investigation that take place among lorry drivers

Functional complement analysis can predict genetic testing results and long-term outcome in patients with complement deficiencies

Background: Prevalence of complement deficiencies (CDs) is markedly higher in Slovenian primary immunodeficiency (PID) registry in comparison to other national and international PID registries. Objective: The purposes of our study were to confirm CD and define complete and partial CD in registered patients in Slovenia, to evaluate frequency of clinical manifestations, and to assess the risk for characteristic infections separately for subjects with complete and partial CD. Methods: CD was confirmed with genetic analyses in patients with C2 deficiency, C8 deficiency, and hereditary angioedema or with repeated functional complement studies and measurement of complement components in other CD. Results of genetic studies (homozygous subjects vs. heterozygous carriers) and complement functional studies were analyzed to define complete (complement below the level of heterozygous carriers) and partial CD (complement above the level of homozygous patients). Presence of characteristic infections was assessed separately for complete and partial CD. Results: Genetic analyses confirmed markedly higher prevalence of CD in Slovenian PID registry (26% of all PID) than in other national and international PID registries (0.5–6% of all PID). Complement functional studies and complement component concentrations reliably distinguished between homozygous and heterozygous CD carriers. Subjects with partial CD had higher risk for characteristic infections than previously reported. Conclusion: Results of our study imply under-recognition of CD worldwide. Complement functional studies and complement component concentrations reliably predicted risk for characteristic infections in patients with complete or partial CD. Vaccination against encapsulated bacteria should be advocated also for subjects with partial CD and not limited to complete CD

Functional Complement Analysis Can Predict Genetic Testing Results and Long-Term Outcome in Patients With Complement Deficiencies

BackgroundPrevalence of complement deficiencies (CDs) is markedly higher in Slovenian primary immunodeficiency (PID) registry in comparison to other national and international PID registries.ObjectiveThe purposes of our study were to confirm CD and define complete and partial CD in registered patients in Slovenia, to evaluate frequency of clinical manifestations, and to assess the risk for characteristic infections separately for subjects with complete and partial CD.MethodsCD was confirmed with genetic analyses in patients with C2 deficiency, C8 deficiency, and hereditary angioedema or with repeated functional complement studies and measurement of complement components in other CD. Results of genetic studies (homozygous subjects vs. heterozygous carriers) and complement functional studies were analyzed to define complete (complement below the level of heterozygous carriers) and partial CD (complement above the level of homozygous patients). Presence of characteristic infections was assessed separately for complete and partial CD.ResultsGenetic analyses confirmed markedly higher prevalence of CD in Slovenian PID registry (26% of all PID) than in other national and international PID registries (0.5–6% of all PID). Complement functional studies and complement component concentrations reliably distinguished between homozygous and heterozygous CD carriers. Subjects with partial CD had higher risk for characteristic infections than previously reported.ConclusionResults of our study imply under-recognition of CD worldwide. Complement functional studies and complement component concentrations reliably predicted risk for characteristic infections in patients with complete or partial CD. Vaccination against encapsulated bacteria should be advocated also for subjects with partial CD and not limited to complete CD

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Background<p>Prevalence of complement deficiencies (CDs) is markedly higher in Slovenian primary immunodeficiency (PID) registry in comparison to other national and international PID registries.</p>Objective<p>The purposes of our study were to confirm CD and define complete and partial CD in registered patients in Slovenia, to evaluate frequency of clinical manifestations, and to assess the risk for characteristic infections separately for subjects with complete and partial CD.</p>Methods<p>CD was confirmed with genetic analyses in patients with C2 deficiency, C8 deficiency, and hereditary angioedema or with repeated functional complement studies and measurement of complement components in other CD. Results of genetic studies (homozygous subjects vs. heterozygous carriers) and complement functional studies were analyzed to define complete (complement below the level of heterozygous carriers) and partial CD (complement above the level of homozygous patients). Presence of characteristic infections was assessed separately for complete and partial CD.</p>Results<p>Genetic analyses confirmed markedly higher prevalence of CD in Slovenian PID registry (26% of all PID) than in other national and international PID registries (0.5–6% of all PID). Complement functional studies and complement component concentrations reliably distinguished between homozygous and heterozygous CD carriers. Subjects with partial CD had higher risk for characteristic infections than previously reported.</p>Conclusion<p>Results of our study imply under-recognition of CD worldwide. Complement functional studies and complement component concentrations reliably predicted risk for characteristic infections in patients with complete or partial CD. Vaccination against encapsulated bacteria should be advocated also for subjects with partial CD and not limited to complete CD.</p