Monitoring of Natura 2000 sites using hyperspectral remote sensing : quality assessment of field and airborne data for Ginkelse & Ederheide and Wekeromse Zand

In 2007, an airborne imaging spectroscopy campaign was organized in the frame of the HABISTAT project. Airborne data with the AHS sensor were acquired in the Netherlands and Belgium. One test site in Belgium was recorded, the Kalmthoutse Heide and one in the Netherlands: the Edese and Ginkelse Heide and the Wekeromse Zand. This report describes the quality assessment of the field and airborne data for the Edese and Ginkelse Heide and the Wekeromse Zand site. The results for the Kalmthoutse Heide will be presented in a separate report (INBO, 2008)

Object identification and characterization with hyperspectral imagery to identify structure and function of Natura 2000 habitats

Habitat monitoring of designated areas under the EU Habitats Directive requires every 6 years information on area, range, structure and function for the protected (Annex I) habitat types. First results from studies on heathland areas in Belgium and the Netherlands show that hyperspectral imagery can be an important source of information to assist the evaluation of the habitat conservation status. Hyperspectral imagery can provide continuous maps of habitat quality indicators (e.g., life forms or structure types, management activities, grass, shrub and tree encroachment) at the pixel level. At the same time, terrain managers, nature conservation agencies and national authorities responsible for the reporting to the EU are not directly interested in pixels, but rather in information at the level of vegetation patches, groups of patches or the protected site as a whole. Such local level information is needed for management purposes, e.g., exact location of patches of habitat types and the sizes and quality of these patches within a protected site. Site complexity determines not only the classification success of remote sensing imagery, but influences also the results of aggregation of information from the pixel to the site level. For all these reasons, it is important to identify and characterize the vegetation patches. This paper focuses on the use of segmentation techniques to identify relevant vegetation patches in combination with spectral mixture analysis of hyperspectral imagery from the Airborne Hyperspectral Scanner (AHS). Comparison with traditional vegetation maps shows that the habitat or vegetation patches can be identified by segmentation of hyperspectral imagery. This paper shows that spectral mixture analysis in combination with segmentation techniques on hyperspectral imagery can provide useful information on processes such as grass encroachment that determine the conservation status of Natura 2000 heathland areas to a large extent. A limitation is that both advanced remote sensing approaches and traditional field based vegetation surveys seem to cause over and underestimations of grass encroachment for specific categories, but the first provides a better basis for monitoring if specific species are not directly considered

Negative control of epithelial cell proliferation by prostatic stroma

Prostatic diseases are rather frequently occurring disorders in the male population. Prostatic adenoma -better known as benign prostatic hyperplasia (BPH)- is the most common benign neoplasm in men. Prostate cancer is the most commonly diagnosed malignancy in men and second leading cause of male cancer death in 'Western countries!. In The Netherlands, the morbidity and mortality caused by this tumor are exceeded only by those originating in lung cancer; in 1991, 4,343 incident cases and 2,108 deaths from cancer of the prostate were recorded in a male population of 7.5 million. The risk of developing prostate cancer increases dramatically with age, as does the oCcurrence of the proliferative disorder BPH. Indeed, men over the age of 65 that do not present with symptoms of prostate cancer during life very frequently are found to contain microscopic malignant lesions upon autopsy. Many patients with prostatic cancer are diagnosed with disseminated disease. The majority of these disseminated prostatic carcinomas are androgen dependent and respond to hormonal manipulation, i.e. medical or surgical castration. The effectiveness of this therapy, however, is only temporary; after an initial response the tumor escapes from endocrine regulation to become insensitive to treatment based on the withdrawal or blockade of androgens. Such patients will eventually die of disseminated hormone-refractory prostate cancer. The etiology of prostate cancer is not clearly defined, it is thought to be multifactorial, involving genetic, hormonal, dietary and environmental causes. The mechanisms leading to progression of prostate tumors to autonomy are also largely unknown. Moreover, despite decades of experience with different treatment modalities, there are still controversies relating to patient selection criteria and choice of treatment. The recent development of different (medical) treatments for BPH has given rise to similar discussions concerning benign enlargement of the gland

Deposition of Drug-delivering Bandages via a Combined Electrostatic and Air-Driven Electrospinning Device

Electrospinning (ES) is an affordable manufacturing process to produce nanoscale, polymer fibers. During ES, a high voltage differential is required to draw out polymer fibers from a polymer solution at a charged spinneret. Fibers produced are then deposited onto an oppositely charged electrode. ES typically requires large, immovable equipment and conductive surfaces for deposition of fibers. Portability and on-demand ES of fiber mats onto non-conductive surfaces would enable use in re- mote locations with limited access to medicine

Gas-Modified Electrospinning with a Portable Device

Project Objective The objective of this work was to construct a miniaturized, portable electrospinning (ES) device for deposition on surfaces regardless of charge. We hope this device can be used by doctors in rural areas to deliver drug delivery bandages. Mathematical modeling was used to improve predictability of the completed portable ES device

Behavior in dogs with spontaneous hypothyroidism during treatment with levothyroxine

Background Thyroid hormone supplementation anecdotally has been described as a valid treatment option for dogs with aggression‐related problems. However, prospective, controlled, and blinded trials evaluating behavior and neurohormonal status in hypothyroid dogs during treatment with levothyroxine are lacking. Objective Levothyroxine supplementation will have a significant influence on the behavior and neurohormonal status of dogs with spontaneous hypothyroidism. Animals Twenty client‐owned dogs diagnosed with spontaneous hypothyroidism. Methods This prospective study was to evaluate the behavior of dogs, which was screened at initial presentation, and after 6 weeks, and 6 months of treatment with levothyroxine (starting dosage 10 μg/kg PO q12h) using the standardized Canine Behavioral Assessment and Research Questionnaire (C‐BARQ). At each time period, circulating serotonin and prolactin (PRL) concentrations were evaluated using a commercially validated ELISA kit and heterologous radioimmunoassay, respectively. Results After 6 weeks of thyroid hormone supplementation, C‐BARQ scores demonstrated a significant increase in activity of hypothyroid dogs (P  .99 and P = .46) and PRL (P = .99 and P = .37) were noted between the 6‐week and 6‐month periods compared with baseline. Conclusions and Clinical Importance The results of this study indicate increased activity of hypothyroid dogs after 6 weeks of thyroid hormone supplementation. None of the hypothyroid dogs in this cohort showed a significant change in any of the evaluated behavioral signs and neurohormonal status after 6 months of thyroid hormone supplementation