GigaGauss solenoidal magnetic field inside of bubbles excited in under-dense plasma

Magnetic fields have a crucial role in physics at all scales, from astrophysics to nanoscale phenomena. Large fields, constant or pulsed, allow investigation of material in extreme conditions, opening up plethora of practical applications based on ultra-fast process, and studying phenomena existing only in exotic astro-objects like neutron stars or pulsars. Magnetic fields are indispensable in particle accelerators, for guiding the relativistic particles along a curved trajectory and for making them radiate in synchrotron light sources and in free electron lasers. In the presented paper we propose a novel and effective method for generating solenoidal quasi-static magnetic field on the GigaGauss level and beyond, in under-dense plasma, using screw-shaped high intensity laser pulses. In comparison with already known techniques which typically rely on interaction with over-dense or solid targets, where radial or toroidal magnetic field localized at the stationary target were generated, our method allows to produce gigantic solenoidal fields, which is co-moving with the driving laser pulse and collinear with accelerated electrons. The solenoidal field is quasi-stationary in the reference frame of the laser pulse and can be used for guiding electron beams and providing synchrotron radiation beam emittance cooling for laser-plasma accelerated electron and positron beams, opening up novel opportunities for designs of the light sources, free electron lasers, and high energy colliders based on laser plasma acceleration.Comment: 15 pages, 9 figures. Main text (without abstract, References and Appendix): 12 page

GigaGauss solenoidal magnetic field inside bubbles excited in under-dense plasma

This paper proposes a novel and effective method for generating GigaGauss level, solenoidal quasi-static magnetic fields in under-dense plasma using screw-shaped high intensity laser pulses. This method produces large solenoidal fields that move with the driving laser pulse and are collinear with the accelerated electrons. This is in contrast with already known techniques which rely on interactions with over-dense or solid targets and generates radial or toroidal magnetic field localized at the stationary target. The solenoidal field is quasi-stationary in the reference frame of the laser pulse and can be used for guiding electron beams. It can also provide synchrotron radiation beam emittance cooling for laser-plasma accelerated electron and positron beams, opening up novel opportunities for designs of the light sources, free electron lasers, and high energy colliders based on laser plasma acceleration

Screening studies of POP levels in bottom sediments from selected lakes in the Paz watercourse

Appendix 5/15 of the publication "State of the environment in the Norwegian, Finnish and Russian border area 2007" (The Finnish Environment 6/2007)

Screening studies of POP levels in fish from selected lakes in the Paz watercourse

Appendix 8/15 of the publication "State of the environment in the Norwegian, Finnish and Russian border area 2007" (The Finnish Environment 6/2007)

Automatic Syringe for Farm Animals Vaccination

Existing injectors use the manual, mechanical or pneumatic drive. These types of drive do not allow making mass vaccination of farm animals automatic. In case of large livestock herd, vaccination is a labour intensive and complicated process. In the livestock sector, mass vaccination is carried out with intervals from several days to several months and depends on the type of animals, their breed and age. If vaccination is not provided or done incorrectly; then the weight gain of animals decreases, and the loss of livestock increases, which causes direct losses to farmers and to livestock enterprises. Therefore, special attention should be given to animals vaccinations, and scientific and technical developments for the vaccination process improvement are relevant worldwide. The developed automatic injector is a stand-alone small hand electric tool. It has an ergonomic design with a convenient location in the hand of a veterinarian and allows you to automate the process of farm animals vaccinations. A distinctive feature of the developed automatic injector is the use of linear electric motor which moves the syringe without the efforts from a veterinarian. The electric drive expands the functionality of the injector, makes the vaccination process less costly and more informative for the veterinary services using RFID identification of farm animals

Trains of electron micro-bunches in plasma wake-field acceleration

Plasma-based charged particle accelerators have been intensively investigated in the past three decades due to their capability to open up new horizons in accelerator science and particle physics yielding electric field accelerating gradient more than three orders of magnitudes higher than in conventional devices. At the current stage the most advanced and reliable mechanism for accelerating electrons is based on the propagation of an intense laser pulse or a relativistic electron beam in a low density gaseous target. In this paper we concentrate on the electron beam-driven plasma wake-field acceleration and demonstrate using 3D PiC simulations that a train of electron micro-bunches with ∼10 fs period can be generated behind the driving beam propagating in a density down-ramp. We will discuss the conditions and properties of the micro-bunches generated aiming at understanding and study of multi-bunch mechanism of injection. It is show that the periodicity and duration of micro-bunches can be controlled by adjusting the plasma density gradient and driving beam charge

Label-Free Protein Detection by Micro-Acoustic Biosensor Coupled with Electrical Field Sorting. Theoretical Study in Urine Models

International audienceDiagnostic devices for point-of-care (POC) urine analysis (urinalysis) based on microfluidic technology have been actively developing for several decades as an alternative to laboratory based biochemical assays. Urine proteins (albumin, immunoglobulins, uromodulin, haemoglobin etc.) are important biomarkers of various pathological conditions and should be selectively detected by urinalysis sensors. The challenge is a determination of different oligomeric forms of the same protein, e.g., uromodulin, which have similar bio-chemical affinity but different physical properties. For the selective detection of different types of proteins, we propose to use a shear bulk acoustic resonator sensor with an additional electrode on the upper part of the bioliquid-filled channel for protein electric field manipulation. It causes modulation of the protein concentration over time in the near-surface region of the acoustic sensor, that allows to distinguish proteins based on their differences in diffusion coefficients (or sizes) and zeta-potentials. Moreover, in order to improve the sensitivity to density, we propose to use structured sensor interface. A numerical study of this approach for the detection of proteins was carried out using the example of albumin, immunoglobulin, and oligomeric forms of uromodulin in model urine solutions. In this contribution we prove the proposed concept with numerical studies for the detection of albumin, immunoglobulin, and oligomeric forms of uromodulin in urine models

Unusual Case of Anaplastic Large Cell Lymphoma Presenting as a Breast Mass in a Patient with no History of Breast Implants

Adenocarcinoma is the most common malignant neoplasm involving breast tissue. In contrast to carcinomas, the other types of malignant neoplasms involving the breast are relatively uncommon. One of the examples of this rare entity is lymphoma. Traditionally, non-Hodgkin lymphomas (NHL) involving the breast are divided into primary lymphoma of the breast and systemic lymphoma, although the distinction could be challenging. Most of NHL involving breast tissue have B cell origin; T cell NHL represents less than 20% of all lymphoma cases. Anaplastic large cell lymphomas (ALCL) involving the breast accounts for even lower percentage of cases. Similar to ALCL involving other sites, there are several main types of ALCL identified: primary cutaneous ALCL and systemic ALCL, which is subdivided into ALK positive and ALK negative subtypes. Relatively recently, an additional distinct subtype of ALK-negative ALCL was described, which is associated with textured breast implants and needs to be considered as a differential diagnosis if patient has a history of breast implants. Here, we report a case of ALCL presented as a breast mass without history of breast implant and discuss similar cases published in the literature

Label-Free Physical Techniques and Methodologies for Proteins Detection in Microfluidic Biosensor Structures

Proteins in biological fluids (blood, urine, cerebrospinal fluid) are important biomarkers of various pathological conditions. Protein biomarkers detection and quantification have been proven to be an indispensable diagnostic tool in clinical practice. There is a growing tendency towards using portable diagnostic biosensor devices for point-of-care (POC) analysis based on microfluidic technology as an alternative to conventional laboratory protein assays. In contrast to universally accepted analytical methods involving protein labeling, label-free approaches often allow the development of biosensors with minimal requirements for sample preparation by omitting expensive labelling reagents. The aim of the present work is to review the variety of physical label-free techniques of protein detection and characterization which are suitable for application in micro-fluidic structures and analyze the technological and material aspects of label-free biosensors that implement these methods. The most widely used optical and impedance spectroscopy techniques: absorption, fluorescence, surface plasmon resonance, Raman scattering, and interferometry, as well as new trends in photonics are reviewed. The challenges of materials selection, surfaces tailoring in microfluidic structures, and enhancement of the sensitivity and miniaturization of biosensor systems are discussed. The review provides an overview for current advances and future trends in microfluidics integrated technologies for label-free protein biomarkers detection and discusses existing challenges and a way towards novel solutions