Radiation Pressure Supported Starburst Disks and AGN Fueling

We consider the structure of marginally Toomre-stable starburst disks under the assumption that radiation pressure on dust grains provides the dominant vertical support against gravity. This is particularly appropriate when the disk is optically thick to its own IR radiation, as in the central regions of ULIRGs. Because the disk radiates at its Eddington limit, the Schmidt-law for star formation changes in the optically-thick limit, with the star formation rate per unit area scaling as Sigma_g/kappa, where Sigma_g is the gas surface density and kappa is the mean opacity. We show that optically thick starburst disks have a characteristic flux and dust effective temperature of F ~ 10^{13} L_sun/kpc^2 and T_eff ~ 90K, respectively. We compare our predictions with observations and find good agreement. We extend our model from many-hundred parsec scales to sub-parsec scales and address the problem of fueling AGN. We assume that angular momentum transport proceeds via global torques rather than a local viscosity. We account for the radial depletion of gas due to star formation and find a strong bifurcation between two classes of disk models: (1) solutions with a starburst on large scales that consumes all of the gas with little fueling of a central AGN and (2) models with an outer large-scale starburst accompanied by a more compact starburst on 1-10 pc scales and a bright central AGN. The luminosity of the latter models is in many cases dominated by the AGN. We show that the vertical thickness of the starburst disk on pc scales can approach h ~ r, perhaps accounting for the nuclear obscuration in some Type 2 AGN. We also argue that the disk of young stars in the Galactic Center may be the remnant of such a compact nuclear starburst.Comment: 26 pages, 9 figures, emulateapj, accepted to ApJ, minor changes, discussion tightened, references adde

An axisymmetric hydrodynamical model for the torus wind in AGN. II: X-ray excited funnel flow

We have calculated a series of models of outflows from the obscuring torus in active galactic nuclei (AGN). Our modeling assumes that the inner face of a rotationally supported torus is illuminated and heated by the intense X-rays from the inner accretion disk and black hole. As a result of such heating a strong biconical outflow is observed in our simulations. We calculate 3-dimensional hydrodynamical models, assuming axial symmetry, and including the effects of X-ray heating, ionization, and radiation pressure. We discuss the behavior of a large family of these models, their velocity fields, mass fluxes and temperature, as functions of the torus properties and X-ray flux. Synthetic warm absorber spectra are calculated, assuming pure absorption, for sample models at various inclination angles and observing times. We show that these models have mass fluxes and flow speeds which are comparable to those which have been inferred from observations of Seyfert 1 warm absorbers, and that they can produce rich absorption line spectra.Comment: 32 pages, 11 figures Accepted for publication in Ap

Neutralizing antibody response during acute and chronic hepatitis C virus infection

Little is known about the role of Abs in determining the outcome of hepatitis C virus (HCV) infection. By using infectious retroviral pseudotypes bearing HCV glycoproteins, we measured neutralizing Ab (nAb) responses during acute and chronic HCV infection. In seven acutely infected health care workers, only two developed a nAb response that failed to associate with viral clearance. In contrast, the majority of chronically infected patients had nAbs. To determine the kinetics of strain-specific and crossreactive nAb emergence, we studied patient H, the source of the prototype genotype 1a H77 HCV strain. An early weak nAb response, specific for the autologous virus, was detected at seroconversion. However, neutralization of heterologous viruses was detected only between 33 and 111 weeks of infection. We also examined the development of nAbs in 10 chimpanzees infected with H77 clonal virus. No nAb responses were detected in three animals that cleared virus, whereas strain-specific nAbs were detected in six of the seven chronically infected animals after approximately 50 weeks of infection. The delayed appearance of high titer crossreactive nAbs in chronically infected patients suggests that selective mechanism(s) may operate to prevent the appearance of these Abs during acute infection. The long-term persistence of these nAbs in chronically infected patients may regulate viral replication

An Eccentric Circumbinary Accretion Disk and the Detection of Binary Massive Black Holes

We present a two-dimensional grid-based hydrodynamic simulation of a thin, viscous, locally-isothermal corotating disk orbiting an equal-mass Newtonian binary point mass on a fixed circular orbit. We study the structure of the disk after multiple viscous times. The binary maintains a central hole in the viscously-relaxed disk with radius equal to about twice the binary semimajor axis. Disk surface density within the hole is reduced by orders of magnitude relative to the density in the disk bulk. The inner truncation of the disk resembles the clearing of a gap in a protoplanetary disk. An initially circular disk becomes elliptical and then eccentric. Disturbances in the disk contain a component that is stationary in the rotating frame in which the binary is at rest; this component is a two-armed spiral density wave. We measure the distribution of the binary torque in the disk and find that the strongest positive torque is exerted inside the central low-density hole. We make connection with the linear theory of disk forcing at outer Lindblad resonances (OLRs) and find that the measured torque density distribution is consistent with forcing at the 3:2 (m=2) OLR, well within the central hole. We also measure the time dependence of the rate at which gas accretes across the hole and find quasi-periodic structure. We discuss implications for variability and detection of active galactic nuclei containing a binary massive black hole.Comment: 10 pages; replaced to match ApJ version; includes new physical interpretation of torque density (Sec. 4.1); large mpeg animation is available at http://www.tapir.caltech.edu/~milos/circBinaryEccDisk.mp

Simulations of Direct Collisions of Gas Clouds with the Central Black Hole

We perform numerical simulations of clouds in the Galactic Centre (GC) engulfing the nuclear super-massive black hole and show that this mechanism leads to the formation of gaseous accretion discs with properties that are similar to the expected gaseous progenitor discs that fragmented into the observed stellar disc in the GC. As soon as the cloud hits the black hole, gas with opposite angular momentum relative to the black hole collides downstream. This process leads to redistribution of angular momentum and dissipation of kinetic energy, resulting in a compact gaseous accretion disc. A parameter study using thirteen high resolution simulations of homogeneous clouds falling onto the black hole and engulfing it in parts demonstrates that this mechanism is able to produce gaseous accretion discs that could potentially be the progenitor of the observed stellar disc in the GC. A comparison of simulations with different equations of state (adiabatic, isothermal and full cooling) demonstrates the importance of including a detailed thermodynamical description. However the simple isothermal approach already yields good results on the radial mass transfer and accretion rates, as well as disc eccentricities and sizes. We find that the cloud impact parameter strongly influences the accretion rate whereas the impact velocity has a small affect on the accretion rate.Comment: 21 pages, 18 figures, Accepted for publication in MNRA

21cm Absorption by Compact Hydrogen Disks Around Black Holes in Radio-Loud Nuclei of Galaxies

The clumpy maser disks observed in some galactic nuclei mark the outskirts of the accretion disk that fuels the central black hole and provide a potential site of nuclear star formation. Unfortunately, most of the gas in maser disks is currently not being probed; large maser gains favor paths that are characterized by a small velocity gradient and require rare edge-on orientations of the disk. Here we propose a method for mapping the atomic hydrogen distribution in nuclear disks through its 21cm absorption against the radio continuum glow around the central black hole. In NGC 4258, the 21cm optical depth may approach unity for high angular-resolution (VLBI) imaging of coherent clumps which are dominated by thermal broadening and have the column density inferred from X-ray absorption data, ~10^{23}/cm^2. Spreading the 21cm absorption over the full rotation velocity width of the material in front of the narrow radio jets gives a mean optical depth of ~0.1. Spectroscopic searches for the 21cm absorption feature in other galaxies can be used to identify the large population of inclined gaseous disks which are not masing in our direction. Follow-up imaging of 21cm silhouettes of accelerating clumps within these disks can in turn be used to measure cosmological distances.Comment: 4 page

The Milky Way's Fermi Bubbles: Echoes of the Last Quasar Outburst?

{\it Fermi}-LAT has recently detected two gamma ray bubbles disposed symmetrically with respect to the Galactic plane. The bubbles have been suggested to be in a quasi-steady state, inflated by ongoing star formation over the age of the Galaxy. Here we propose an alternative picture where the bubbles are the remnants of a large-scale wide-angle outflow from \sgra, the SMBH of our Galaxy. Such an outflow would be a natural consequence of a short but bright accretion event on to \sgra\ if it happened concurrently with the well known star formation event in the inner 0.5 pc of the Milky Way $\sim 6$ Myr ago. We find that the hypothesised near-spherical outflow is focussed into a pair of symmetrical lobes by the greater gas pressure along the Galactic plane. The outflow shocks against the interstellar gas in the Galaxy bulge. Gamma--ray emission could be powered by cosmic rays created by either \sgra\ directly or accelerated in the shocks with the external medium. The Galaxy disc remains unaffected, agreeing with recent observational evidence that supermassive black holes do not correlate with galaxy disc properties. We estimate that an accreted mass \sim 2 \times 10^3\msun is needed for the accretion event to power the observed {\it Fermi}--LAT lobes. Within a factor of a few this agrees with the mass of the young stars born during the star formation event. This estimate suggests that roughly 50% of the gas was turned into stars, while the rest accreted onto \sgra. One interpretation of this is a reduced star formation efficiency inside the \sgra\ accretion disc due to stellar feedback, and the other a peculiar mass deposition geometry that resulted in a significant amount of gas falling directly inside the inner $\sim 0.03$ pc of the Galaxy.Comment: 6 pages, 0 figures; accepted for publication in MNRA

Star formation in self-gravitating disks in active galactic nuclei. I. Metallicity gradients in broad line regions

It has been suggested that the high metallicity generally observed in active galactic nuclei (AGNs) and quasars originates from ongoing star formation in the self-gravitating part of accretion disks around the supermassive black holes. We designate this region as the star forming (SF) disk, in which metals are produced from supernova explosions (SNexp) while at the same time inflows are driven by SNexp-excited turbulent viscosity to accrete onto the SMBHs. In this paper, an equation of metallicity governed by SNexp and radial advection is established to describe the metal distribution and evolution in the SF disk. We find that the metal abundance is enriched at different rates at different positions in the disk, and that a metallicity gradient is set up that evolves for steady-state AGNs. Metallicity as an integrated physical parameter can be used as a probe of the SF disk age during one episode of SMBH activity. In the SF disk, evaporation of molecular clouds heated by SNexp blast waves unavoidably forms hot gas. This heating is eventually balanced by the cooling of the hot gas, but we show that the hot gas will escape from the SF disk before being cooled, and diffuse into the BLRs forming with a typical rate of \sim 1\sunmyr. The diffusion of hot gas from a SF disk depends on ongoing star formation, leading to the metallicity gradients in BLR observed in AGNs. We discuss this and other observable consequences of this scenario.Comment: 11 pages, 5 Figures, ApJ, Vol. 737, in pres

A combined model for the X-ray to gamma-ray emission of Cyg X-1

We use recent data obtained by three (OSSE, BATSE, and COMPTEL) of four instruments on board the Compton Gamma Ray Observatory, to construct a model of Cyg X-1 which describes its emission in a broad energy range from soft X-rays to MeV gamma-rays self-consistently. The gamma-ray emission is interpreted to be the result of Comptonization, bremsstrahlung, and positron annihilation in a hot optically thin and spatially extended region surrounding the whole accretion disk. For the X-ray emission a standard corona-disk model is applied. We show that the Cyg X-1 spectrum accumulated by the CGRO instruments during a ~4 year time period between 1991 and 1995, as well as the HEAO-3 gamma1 and gamma2 spectra can be well represented by our model. The derived parameters match the observational results obtained from X-ray measurements.Comment: 11 pages including 6 ps-figures and 2 tables, latex2e, uses emulateapj.sty (ver. of 18 Sep 96, enclosed), epsfig.sty, times.sty. To appear in July 20, 1998 issue of ApJ (v.502

HERPESVIRUS INFECTIONS AND CLINICAL-IMMUNOLOGIC INTERACTIONS IN PATIENTS WITH EARLY-ONSET ALZHEIMER’S DISEASE AND LATE-ONSET ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is currently the most common cause of dementia. A significant role in the pathogenesis of AD belongs to the activation of the mechanisms of neuroinflammation. There is a hypothesis that chronic infections may play a role in the maintenance of the inflammatory response in AD. The aim of this work was to study the detection rate and DNA level of herpesviruses, as well as their possible relationship with the level of the key cytokines and with clinical parameters of AD in patients with early and late onset. 30 patients with AD and 33 healthy volunteers were enrolled. The quantitative determination of DNA of CMV, EBV, HHV-6, HHV-7 was carried out by PCR. The level of cytokines and soluble IL-1β antagonist (IL-1ra) in the blood was determined by ELISA. Herpesvirus infection with increased viral load was determined if at least one of the criteria was present: 1) DNA level of EBV and/or HHV-6 > 10,000 copies/ml in saliva; 2) presence of DNA of at least one of the EBV, HHV-6, HHV-7 viruses in the blood. In the subgroup of patients with early onset and increased viral load, there was a higher increase in the levels of a number of cytokines: proinflammatory IL-8 and IL-12, a Th2-cytokine IL-4, a cytokine of the adaptive immune response IL-2. However, the level of the anti-inflammatory protein IL-1ra was lower than in the controls. These changes may indicate a dysregulation of the antiviral response, with a predominance of activation of systemic inflammation and Th2-mediated reactions. Also, in early onset AD the increased viral load was associated with lower scores on Boston naming test. The results indicate that in studies of AD mechanisms and in the search for prognostic markers of the disease, it is important to take into account the heterogeneity of AD in terms of genetic predisposition factors, risk factors, immune parameters and clinical data. Such approach is necessary for the subsequent development of personalized approaches to the prevention and treatment of AD