Classification of Electroencephalograph Data: A Hubness-aware Approach

Classification of electroencephalograph (EEG) data is the common denominator in various recognition tasks related to EEG signals. Automated recognition systems are especially useful in cases when continuous, long-term EEG is recorded and the resulting data, due to its huge amount, cannot be analyzed by human experts in depth. EEG-related recognition tasks may support medical diagnosis and they are core components of EEGcontrolled devices such as web browsers or spelling devices for paralyzed patients. Stateof-the-art solutions are based on machine learning. In this paper, we show that EEG datasets contain hubs, i.e., signals that appear as nearest neighbors of surprisingly many signals. This paper is the first to document this observation for EEG datasets. Next, we argue that the presence of hubs has to be taken into account for the classification of EEG signals, therefore, we adapt hubness-aware classifiers to EEG data. Finally, we present the results of our empirical study on a large, publicly available collection of EEG signals and show that hubness-aware classifiers outperform the state-of-the-art time-series classifier

ChIPSummitDB:a ChIP-seq-based database of human transcription factor binding sites and the topological arrangements of the proteins bound to them.

ChIP-seq reveals genomic regions where proteins, e.g. transcription factors (TFs) interact with DNA. A substantial fraction of these regions, however, do not contain the cognate binding site for the TF of interest. This phenomenon might be explained by protein-protein interactions and co-precipitation of interacting gene regulatory elements. We uniformly processed 3727 human ChIP-seq data sets and determined the cistrome of 292 TFs, as well as the distances between the TF binding motif centers and the ChIP-seq peak summits. ChIPSummitDB enables the analysis of ChIP-seq data using multiple approaches. The 292 cistromes and corresponding ChIP-seq peak sets can be browsed in GenomeView. Overlapping SNPs can be inspected in dbSNPView. Most importantly, the MotifView and PairShiftView pages show the average distance between motif centers and overlapping ChIP-seq peak summits and distance distributions thereof, respectively. In addition to providing a comprehensive human TF binding site collection, the ChIPSummitDB database and web interface allows for the examination of the topological arrangement of TF complexes genome-wide. ChIPSummitDB is freely accessible at http://summit.med.unideb.hu/summitdb/. The database will be regularly updated and extended with the newly available human and mouse ChIP-seq data sets

Identification and analysis of the distribution chain of the seedless citric fruits : a case study in São Paulo city

O objetivo deste trabalho foi identificar mecanismos de comercialização para as frutas cítricas, de mesa, sem sementes, provenientes dos municípios de São Gabriel, Santa Margarida do Sul e Rosário do Sul, situados no limite norte da metade sul do Estado do Rio Grande do Sul. O método de pesquisa foi um estudo de caso, de caráter exploratório, em que foram entrevistados dez comerciantes na cidade de São Paulo. Constatou-se que há comerciantes que importam frutas cítricas do Uruguai e da Espanha para abastecer o mercado interno e que esses, em sua maioria, estão interessados em substituir as importações por frutas produzidas no Brasil, desde que possuam qualidade semelhante à das frutas importadas e preço mais baixo. A Central de Abastecimento (CEAGESP) é o estabelecimento que, num mesmo lugar, responde pelo maior volume de frutas distribuídas. Neste estudo, determinou-se a configuração da cadeia de distribuição das frutas cítricas sem sementes.This research aims at identifying commercial mechanisms for in nature seedless citric fruits which are produced in São Gabriel, Santa Margarida do Sul and Rosário do Sul, cities located in the north boundary of the southern half of the state of Rio Grande do Sul. The research method consisted of an exploratory case study, in which ten traders were interviewed in São Paulo city. It has been noticed that in São Paulo there are traders who import citric fruit from Uruguay and Spain in order to supply the domestic market, and most of them would like to replace such imports for fruits produced in Brazil as long as similar quality and lower prices can be achieved. The CEAGESP (Food Supply Distribution Center) is the establishment that, in a single place, accounts for the highest volume of fruit distribution. In this study the configuration of the distribution chain of seedless citric fruits was set up

Evolution of the middle crust beneath the western Pannonian Basin: A xenolith study

Felsic to mafic granulite xenoliths from late Neogene basalt pyroclastics in four localities of the western Pannonian Basin (Beistein, Kapfenstein, Szigliget and Káptalantóti (Sabar-hegy) were studied to find out their metamorphic and fluid history. The characteristic mineral assemblage of the granulites consists of Pl + Opx + Qtz ± Cpx ± Bt ± Grt ± Kfs. Based on abundant magmatic relic microstructural domains occurring in these rocks, the potential precursors might have been predominantly felsic igneous or high to ultrahigh temperature rocks. Ternary feldspar thermometry provides a rough estimate of temperatures of about 920-1070 °C. The first fluid invasion event, which is linked with this early high to ultrahigh temperature stage is characterised by primary pure CO2 inclusions in apatite and zircon. The densest primary CO2 inclusions indicate 0.52-0.64 GPa pressure at the estimated temperature range of crystallization. According to mineral equilibria and geothermobarometry, the high to ultrahigh temperature rock cooled and crystallized to granulite of predominantly felsic composition at about 750-870 °C and 0.50-0.75 GPa in the middle crust, between 20 and 29 km depths. The second fluid invasion event is recorded by primary CO2-rich fluid inclusions hosted in the granulitic mineral assemblage (plagioclase, quartz and orthopyroxene). In addition to CO2, Raman spectroscopy revealed the presence of minor N2, H2S, CO and H2O in these inclusions. Partial melting of biotite-bearing assemblages could be connected to the next fluid invasion shown by secondary CO2-rich fluids recorded along with healed fractures in plagioclase, clinopyroxene and orthopyroxene. This event could have happened at depths similar to the previous ones. The final step in the granulite evolution was the sampling in the middle crust and transportation to the surface in form of xenoliths by mafic melt. This event generated temperature increase and pressure decrease and thus, limited melting of the xenoliths. The youngest fluid inclusion generation, observed mostly in healed fractures of felsic minerals, could be associated with this event. © 2013 Springer-Verlag Wien

A trajetória das crianças e adolescentes vítimas de violência sexual : fatores de risco e proteção

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A trajetória das crianças e adolescentes vítimas de violência sexual : fatores de risco e proteção

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