167 research outputs found

    ALMA Lensing Cluster Survey: Hubble Space Telescope and Spitzer Photometry of 33 Lensed Fields Built with CHArGE

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    We present a set of multiwavelength mosaics and photometric catalogs in the Atacama Large Millimeter/ submillimeter Array (ALMA) lensing cluster survey fields. The catalogs were built by the reprocessing of archival data from the Complete Hubble Archive for Galaxy Evolution compilation, taken by the Hubble Space Telescope (HST) in the Reionization Lensing Cluster Survey, Cluster Lensing And Supernova survey with Hubble, and Hubble Frontier Fields. Additionally, we have reconstructed the Spitzer Infrared Array Camera 3.6 and 4.5 μm mosaics, by utilizing all the available archival IPAC Infrared Science Archive/Spitzer Heritage Archive exposures. To alleviate the effect of blending in such a crowded region, we have modeled the Spitzer photometry by convolving the HST detection image with the Spitzer point-spread function using the novel GOLFIR software. The final catalogs contain 218,000 sources, covering a combined area of 690 arcmin2, a factor of ∼2 improvement over the currently existing photometry. A large number of detected sources is a result of reprocessing of all available and sometimes deeper exposures, in conjunction with a combined optical–near-IR detection strategy. These data will serve as an important tool in aiding the search of the submillimeter galaxies in future ALMA surveys, as well as follow-ups of the HST dark and high-z sources with JWST. Coupled with the available HST photometry, the addition of the 3.6 and 4.5 μm bands will allow us to place a better constraint on the photometric redshifts and stellar masses of these objects, thus giving us an opportunity to identify high-redshift candidates for spectroscopic follow-ups and to answer the important questions regarding the Epoch of Reionization and formation of the first galaxies. The mosaics, photometric catalogs, and the best-fit physical properties are publicly available at https:// github.com/dawn-cph/alcs-clusters.Danmarks Grundforskningsfond 140Villum Fonden 13160 37440Carlsberg Foundation CF18-0388European Commission 896225 European Research Council (ERC) European Commission 648179Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT) Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) JP17H06130NAOJ ALMA Scientific Research 2017-06BNRAO Student Observing Support (SOS) SOSPA7-022Beatriz Galindo senior fellowship BG20/00224Ministry of Science and Innovation, Spain (MICINN) PID2020-114414GB-100 PID2020-113689GB-I00Junta de Andalucia P20_00334 FEDER/Junta de Andalucia-Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades -FQM-510-UGR20RELICS Treasury Program GO 14096National Aeronautics & Space Administration (NASA) NAS5-2655

    Regional Aspects of Nosocomial Infection As a Medical and Social Problem

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    Prevention of nosocomial infection (NI) is an important medical and socioeconomic problem. And though certain organizational and practical measures are implemented in Russia every year to reduce NIs, the problem is still relevant from medical and social points of view. The risk of infection are both for patients and medical workers. In Russia, the minimum economic damage caused by NIs is 2.5–5 billion rubles annually. According to the Office of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Republic of Mordovia, the total incidence of NI in the region is at a low level. The incidence rate was 0.01 per 1000 patients in hospitals. The dynamics of the last five years demonstrates a decrease in hospital-acquired infections. In the dynamics of the last five years, incidence rates of purulent-septic infections of newborns and postpartum women, postoperative purulent-septic complications and post-injection complications had an unstable downward trend. Thus, purulent-septic infections of newborns and postpartum women and postoperative infections are dominated in the structure of nosocomial infections. Analysis of dynamics of morbidity in recent years in the Republic of Mordovia suggests that the measures taken to prevent NI are quite effective and are manifested with consistently low rates

    Structural Features of TiNi-based Textile Materials and Their Biocompatibility with Cell Culture

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    This study investigates the structural features of TiNi-based textile materials. It is established that woven materials have a regular cellular structure, while knitted mesh materials are characterized by presence of cells with various sizes both in the longitudinal and cross directions. The surface oxide layer of threads has a microporous structure that provides the improved adaptation in organism tissues. It is shown that the fibroblast colonization rate of the knitted mesh implants depends on the cell size and quantity of mesh knots. Smaller cells are quicker colonized. Mesh knots are the centers of the cell cling. The feature of cell interaction with the tread surface of various sizes is analyzed

    Study of structural features of porous TiNi-based materials produced by SHS and sintering

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    Structural properties of porous TiNi-based materials produced by SHS method and sintering have been investigated. The material having different pore wall surface topography, porosity and pore size distribution was shown to be produced depending on the powder metallurgy method for porous TiNi-based alloy. All the materials having porosity of 55-70%, mean pore size 90-150 μm, as well as normal pore size distribution are most preferable. Ultimate strength and breaking point were determined to depend on porosity, pore size distribution, pore intersections and phase chemical composition of the material. Strength properties of the sintered alloy are twice as much compared to the SHS-produced ones due to homogeneity of its macrostructure, low chemical heterogeneity and TiNi3 precipitations strengthening the TiNi matrix.</jats:p

    Effect of modified surface and architectonics of porous-permeable TiNi-based alloy scaffold on cellular biocompatibility

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    Cellular scaffolds based on porous biomaterials play an important role in the engineering of various tissues. Our porous-permeable cellular TiNi-based alloy scaffolds combine the advantages of metal structures, hardness, wear resistance and elasticity similar to that of human tissues. The aim of the research was the study on the change in the surface layer of samples from TiNi-based alloy and on the biotesting of modified samples with the 3H3 fibroblast line. Materials and methods: The biocompatibility of several samples of TiNi-based alloy scaffolds with an average pore size of 83,150,365 μm with modified (acid treatment) surface with 3H3 fibroblast line. Results. The porous-permeable cellular TiNi-based alloy scaffolds (average pore size = 150 μm) modified by treatment with solution of concentrated acids exhibited the highest biocompatibility with a fibroblast culture. It was shown that hemolysis of TiNi-based alloy samples, which are intact and treated with solution of concentrated acids, does not exceed 2 %. Direct cultivation of modified samples with fibroblast line in the cytotoxic test showed low cytotoxicity of the tested cells. The studies carried out using a scanning microscope showed that mesenchymal cells of bone marrow are attached in sufficient quantities to the microporous surface of the modified samples, which allows them to grow and proliferate in the pore space of TiNi-based alloy scaffolds and to cultivate tissue in vitro. Conclusion. Samples of scaffolds manufactured by the SHS-method and modified by treatment with concentrated solution of acids are technological and perspective biomaterial for their use as implantable clinically useful scaffolds

    Functional characteristics of tissue equivalents of various tissues using porous-permeable incubators of titanium nickelide

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    Pancreas cages form a functional fabric and allocate hormonal substances necessary for indemnification of the lost structures of a pancreas of an organism. And, at input in an organism of ß-cells deprived of a substrate, life cycle transplanted xenogeneic cages considerably decreases under the influence of immune factors, during too time of a cage in an incubator function longer time, promoting construction of spatial architecture of new gland. The given methodology is effective in diabetes treatment as the transplanted cages it is very thin react to allocation of insulin depending on a condition homeostatic organism systems that is an actual problem at introduction of injections of insulin. Results of researches show that incubators of titanium nickelide are highly effective for their use as biocompatible matrixes. Features incubator spaces, and also a material titanium nickelide the titan promote creation fabric biosystems from various cages of an organism and to considerable prolongation of functional activity transplantation cages that accordingly conducts to increase in period of validity of therapeutic effect. Investigation have shown the formation of specific tissues in porous-permeable incubators of titanium nickelide for different cell populations. Allogeneic bone marrow cells immobilized in incubators of titanium nickelide possess antitumor (25%) and significant antimetastatic (45%) effect. The study of morphological parameters immunocompetent organs showed that administration of allogeneic bone marrow cells can decrease thymic regression, reduces splenomegaly in animals with transplantable tumors. Hepatocytes were implanted in porous materials of titanium nickelide mice with CCl4-induced hepatitis provided significant antitoxic effect. Obtained initial results promising pancreatic tissue-engineering in complex treatment of diabetes. It is noted that the use of incubators permeable porous nickel-titanium increase therapeutic effect and significantly prolongs effect of transplanted cells, as opposed their injecting

    Combined transplantation of hepatocytes with mesenchimal stem cells of bone marrow on porous-permeable TiNi-based alloy scaffold

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    The aim of the research was to study of the therapeutic efficacy of combined transplantation of liver cells and mesenchymal stem cells of bone marrow (MSC) on TiNi-based alloy scaffolds of rats with chronic hepatitis. Materials and methods: Three groups of experiments were carried out on Wistar rats and intact rats (control) - I group; in the II group - chronic hepatitis; III group - cell-engineering designs with liver cells; in the IV group - cell-engineering designs with liver cells and BM MMSC. The activity of recovery processes was evaluated by using biochemical methods in dynamics on 10, 20, 30th days. Results. The optimal ratio of liver cells to MSC (5:1) was previously found in TiNi-based alloy scaffolds after transplantation and through co-cultivation of hepatocytes and MSC at different ratios. It was shown that recovery processes in the group with scaffolds transplanted into damaged livers were much more active if compared with those in the control group with chronic hepatitis. At the same time, in the group with combined transplantation on TiNi-based alloy scaffolds contributed to a more rapid normalization of liver enzyme indices compared with the group with transplantation of some hepatocytes on scaffolds. These data are confirmed by an increase in the life span of animals with combined hepatocytes and MSC transplantation on TiNi-based alloy scaffolds. Conclusions. A higher level and prolonged periods of liver regeneration during the transplantation of TiNi-based alloy scaffolds are due to the creation of biologically appropriate conditions for cells with certain ratio

    Міжпартійне протистояння євроатлантичній орієнтації в країнах Балтії

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    Кокорєв О. В. Міжпартійне протистояння євроатлантичній орієнтації в країнах Балтії / О. В. Кокорєв // S.P.A.C.E. Society, Politics, Administration in Central Europe : електронний науково-практичний журнал / редкол.: Д. В. Яковлев (голов. ред.), К. М. Вітман (заст. голов. ред.), Д. Ю. Дворніченко (відп. секр.) [та ін.] ; НУ «ОЮА». – Одеса, 2017. – Вип. 2. – С. 33-36.У статті проводиться аналіз особливостей політичних партій і їхніх можливостей із формування нової урядової коаліції. Проаналізовано зовнішньополітичне питання євроатлантичної орієнтації. Виявлено відмінності в оцінках зовнішньополітичного курсу.В статье проводится анализ особенностей политических партий и их возможностей по формированию новой правительственной коалиции. Проанализирован внешнеполитический вопрос евроатлантической ориентации. Выявлены различия в оценках внешнеполитического курса.The article analyzes the features of the political parties and the possibility of forming a new coalition government. It analyzes the foreign policy issue of Euro-Atlantic orientation. The differences in the estimates of foreign policy
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