125 research outputs found
1998 Superoutburst of the Large-Amplitude SU UMa-Type Dwarf Nova WX Ceti
We observed the 1998 November superoutburst of WX Cet, a dwarf nova
originally proposed as a WZ Sge-like system. The observation established that
WX Cet is an SU UMa-type dwarf nova with a mean superhump period of 0.05949(1)
d, which is 2.1% longer than the reported orbital period. The lack of early
superhumps at the earliest stage of the superoutburst, the rapid development of
usual superhumps, and the possible rapid decay of late superhumps seem to
support that WX Cet is a fairly normal large-amplitude SU UMa-type dwarf nova,
rather than a WZ Sge-type dwarf nova with a number of peculiarities. However, a
period increase of superhumps at a rate dot(P)/P = (+8.5+/-1.0) x 10^-5 was
observed, which is one of the largest dot(P)/P ever observed in SU UMa-type
dwarf novae. A linear decline of light, with a rate of 0.10 mag/d, was observed
in the post-superoutburst stage. This may be an exemplification of the decay of
the viscosity in the accretion disk after the termination of a superoutburst,
mechanism of which is proposed to explain a variety of post-superoutburst
phenomena in some SU UMa-type dwarf novae.Comment: 8 pages, 8 figures, accepted for publication in Publ. Astron. Soc.
Japa
Welding of Aluminum Alloy with High Power Direct Diode Laser(Physics, Processes, Instruments & Measurements)
Dwarf Nova-like Outburst of Short Period Intermediate Polar HT Camelopardalis
We report the first time-series observations of the short outburst of the
proposed intermediate polar HT Cam (=RX J0757.0+6306). On 2001 December 29, we
detected the object was undergoing a bright outburst at the magnitude of
. Following this detection, we started international joint
observations through VSNET. The light curve showed a gradual decline for the
first 0.5 d. Following this short plateau phase, the rate of decline
dramatically increased to more than 4 mag d. Within 1.5 d from the
outburst detection, the object almost declined to the quiescent level. During
the rapidly declining phase, long-term modulations with a period of 86 min and
strong pulses with a period of 8.6 min were observed. We concluded that 86 min
and 8.6 min are the orbital period and the spin period of HT Cam, respectively.
By the detection of the spin period, we confirmed the IP classification of HT
Cam. However, its outburst behavior rather resembles that of dwarf novae.
The discrepancy between the declining rates of the total flux and the pulse
flux strongly suggests that the disk instabilities were taking place during the
outburst.Comment: 7 pages, 8 figures, accepted for publication in PAS
Long-term monitoring of the short period SU UMa-type dwarf nova, V844 Herculis
We report on time-resolved CCD photometry of four outbursts of a short-period
SU UMa-type dwarf nova, V844 Herculis. We successfully determined the mean
superhump periods to be 0.05584(64) days, and 0.055883(3) for the 2002 May
superoutburst, and the 2006 April-May superoutburst, respectively. During the
2002 October observations, we confirmed that the outburst is a normal outburst,
which is the first recorded normal outburst in V844 Her. We also examined
superhump period changes during 2002 May and 2006 April-May superoutbursts,
both of which showed increasing superhump period over the course of the plateau
stage. In order to examine the long-term behavior of V844 Her, we analyzed
archival data over the past ten years since the discovery of this binary.
Although photometry is not satisfactory in some superoutbursts, we found that
V844 Her showed no precursors and rebrightenings. Based on the long-term light
curve, we further confirmed V844 Her has shown almost no normal outbursts
despite the fact that the supercycle of the system is estimated to be about 300
days. In order to explain the long-term light curves of V844 Her, evaporation
in the accretion disk may play a role in the avoidance of several normal
outbursts, which does not contradict with the relatively large X-ray luminosity
of V844 Her.Comment: 10 pages, 11 figures, accepted for PAS
Spatial Periodicity of Galaxy Number Counts, CMB Anisotropy, and SNIa Hubble Diagram Based on the Universe Accompanied by a Non-Minimally Coupled Scalar Field
We have succeeded in establishing a cosmological model with a non-minimally
coupled scalar field that can account not only for the spatial
periodicity or the {\it picket-fence structure} exhibited by the galaxy -
relation of the 2dF survey but also for the spatial power spectrum of the
cosmic microwave background radiation (CMB) temperature anisotropy observed by
the WMAP satellite. The Hubble diagram of our model also compares well with the
observation of Type Ia supernovae. The scalar field of our model universe
starts from an extremely small value at around the nucleosynthesis epoch,
remains in that state for sufficiently long periods, allowing sufficient time
for the CMB temperature anisotropy to form, and then starts to grow in
magnitude at the redshift of , followed by a damping oscillation
which is required to reproduce the observed picket-fence structure of the
- relation. To realize such behavior of the scalar field, we have found
it necessary to introduce a new form of potential , with being a constant. Through this parameter ,
we can control the epoch at which the scalar field starts growing.Comment: 19 pages, 18 figures, Accepted for publication in Astrophysics &
Space Scienc
Survey of Period Variations of Superhumps in SU UMa-Type Dwarf Novae
We systematically surveyed period variations of superhumps in SU UMa-type
dwarf novae based on newly obtained data and past publications. In many
systems, the evolution of superhump period are found to be composed of three
distinct stages: early evolutionary stage with a longer superhump period,
middle stage with systematically varying periods, final stage with a shorter,
stable superhump period. During the middle stage, many systems with superhump
periods less than 0.08 d show positive period derivatives. Contrary to the
earlier claim, we found no clear evidence for variation of period derivatives
between superoutburst of the same object. We present an interpretation that the
lengthening of the superhump period is a result of outward propagation of the
eccentricity wave and is limited by the radius near the tidal truncation. We
interpret that late stage superhumps are rejuvenized excitation of 3:1
resonance when the superhumps in the outer disk is effectively quenched. Many
of WZ Sge-type dwarf novae showed long-enduring superhumps during the
post-superoutburst stage having periods longer than those during the main
superoutburst. The period derivatives in WZ Sge-type dwarf novae are found to
be strongly correlated with the fractional superhump excess, or consequently,
mass ratio. WZ Sge-type dwarf novae with a long-lasting rebrightening or with
multiple rebrightenings tend to have smaller period derivatives and are
excellent candidate for the systems around or after the period minimum of
evolution of cataclysmic variables (abridged).Comment: 239 pages, 225 figures, PASJ accepte
Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review
BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that commonly has a lethal course caused by the tick-borne Huaiyangshan banyang virus [former SFTS virus (SFTSV)]. The viral load in various body fluids in SFTS patients and the best infection control measure for SFTS patients have not been fully established. CASE PRESENTATION: A 79-year-old man was bitten by a tick while working in the bamboo grove in Nagasaki Prefecture in the southwest part of Japan. Due to the occurrence of impaired consciousness, he was referred to Nagasaki University Hospital for treatment. The serum sample tested positive for SFTSV-RNA in the genome amplification assay, and he was diagnosed with SFTS. Furthermore, SFTSV-RNA was detected from the tick that had bitten the patient. He was treated with multimodal therapy, including platelet transfusion, antimicrobials, antifungals, steroids, and continuous hemodiafiltration. His respiration was assisted with mechanical ventilation. On day 5, taking the day on which he was hospitalized as day 0, serum SFTSV-RNA levels reached a peak and then decreased. However, the cerebrospinal fluid collected on day 13 was positive for SFTSV-RNA. In addition, although serum SFTSV-RNA levels decreased below the detectable level on day 16, he was diagnosed with pneumonia with computed tomography. SFTSV-RNA was detected in the bronchoalveolar lavage fluid on day 21. By day 31, he recovered consciousness completely. The pneumonia improved by day 51, but SFTSV-RNA in the sputum remained positive for approximately 4 months after disease onset. Strict countermeasures against droplet/contact infection were continuously conducted. CONCLUSIONS: Even when SFTSV genome levels become undetectable in the serum of SFTS patients in the convalescent phase, the virus genome remains in body fluids and tissues. It may be possible that body fluids such as respiratory excretions become a source of infection to others; thus, careful infection control management is needed
産後うつとボンディングの関連の経産による変化: 子どもの健康と環境に関する全国調査からの経時的な結果より
富山大学・富医薬博乙77号・土田 暁子・2020/11/25関連論文Tsuchida A, Hamazaki K, Matsumura K, Miura K, Kasamatsu H, Inadera H; Japan Environment and Children\u27s Study (JECS) Group. Changes in the association between postpartum depression and mother-infant bonding by parity: Longitudinal results from the Japan Environment and Children\u27s Study. J Psychiatr Res. 2019 Mar;110:110-116. doi: 10.1016/j.jpsychires.2018.11.022. Epub 2018 Nov 28. PMID: 30616158.富山大
DOCK2 is involved in the host genetics and biology of severe COVID-19
「コロナ制圧タスクフォース」COVID-19疾患感受性遺伝子DOCK2の重症化機序を解明 --アジア最大のバイオレポジトリーでCOVID-19の治療標的を発見--. 京都大学プレスリリース. 2022-08-10.Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge. Here we conducted a genome-wide association study (GWAS) involving 2, 393 cases of COVID-19 in a cohort of Japanese individuals collected during the initial waves of the pandemic, with 3, 289 unaffected controls. We identified a variant on chromosome 5 at 5q35 (rs60200309-A), close to the dedicator of cytokinesis 2 gene (DOCK2), which was associated with severe COVID-19 in patients less than 65 years of age. This risk allele was prevalent in East Asian individuals but rare in Europeans, highlighting the value of genome-wide association studies in non-European populations. RNA-sequencing analysis of 473 bulk peripheral blood samples identified decreased expression of DOCK2 associated with the risk allele in these younger patients. DOCK2 expression was suppressed in patients with severe cases of COVID-19. Single-cell RNA-sequencing analysis (n = 61 individuals) identified cell-type-specific downregulation of DOCK2 and a COVID-19-specific decreasing effect of the risk allele on DOCK2 expression in non-classical monocytes. Immunohistochemistry of lung specimens from patients with severe COVID-19 pneumonia showed suppressed DOCK2 expression. Moreover, inhibition of DOCK2 function with CPYPP increased the severity of pneumonia in a Syrian hamster model of SARS-CoV-2 infection, characterized by weight loss, lung oedema, enhanced viral loads, impaired macrophage recruitment and dysregulated type I interferon responses. We conclude that DOCK2 has an important role in the host immune response to SARS-CoV-2 infection and the development of severe COVID-19, and could be further explored as a potential biomarker and/or therapeutic target
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
「コロナ制圧タスクフォース」COVID-19患者由来の血液細胞における遺伝子発現の網羅的解析 --重症度に応じた遺伝子発現の変化には、ヒトゲノム配列の個人差が影響する--. 京都大学プレスリリース. 2022-08-23.Coronavirus disease 2019 (COVID-19) is a recently-emerged infectious disease that has caused millions of deaths, where comprehensive understanding of disease mechanisms is still unestablished. In particular, studies of gene expression dynamics and regulation landscape in COVID-19 infected individuals are limited. Here, we report on a thorough analysis of whole blood RNA-seq data from 465 genotyped samples from the Japan COVID-19 Task Force, including 359 severe and 106 non-severe COVID-19 cases. We discover 1169 putative causal expression quantitative trait loci (eQTLs) including 34 possible colocalizations with biobank fine-mapping results of hematopoietic traits in a Japanese population, 1549 putative causal splice QTLs (sQTLs; e.g. two independent sQTLs at TOR1AIP1), as well as biologically interpretable trans-eQTL examples (e.g., REST and STING1), all fine-mapped at single variant resolution. We perform differential gene expression analysis to elucidate 198 genes with increased expression in severe COVID-19 cases and enriched for innate immune-related functions. Finally, we evaluate the limited but non-zero effect of COVID-19 phenotype on eQTL discovery, and highlight the presence of COVID-19 severity-interaction eQTLs (ieQTLs; e.g., CLEC4C and MYBL2). Our study provides a comprehensive catalog of whole blood regulatory variants in Japanese, as well as a reference for transcriptional landscapes in response to COVID-19 infection
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