HT Cas - eclipsing dwarf nova during its superoutburst in 2010

We present results of a world-wide observing campaign of the eclipsing dwarf nova - HT Cas during its superoutburst in November 2010. Using collected data we were able to conduct analysis of the light curves and we calculated $O-C$ diagrams. The CCD photometric observations enabled us to derive the superhump period and with the timings of eclipses the orbital period was calculated. Based on superhump and orbital period estimations the period excess and mass ratio of the system were obtained

IX Draconis - a curious ER UMa-type dwarf nova

We report results of an extensive world-wide observing campaign devoted to a very active dwarf nova star - IX Draconis. We investigated photometric behaviour of the system to derive its basic outburst properties and understand peculiarities of IX Dra as well as other active cataclysmic variables, in particular dwarf novae of the ER Uma-type. In order to measure fundamental parameters of the system, we carried out analyses of the light curve, O-C diagram, and power spectra. During over two months of observations we detected two superoutbursts and several normal outbursts. The V magnitude of the star varied in the range 14.6 - 18.2 mag. Superoutbursts occur regularly with the supercycle length of 58.5+/-0.5 d. When analysing data over the past 20 years, we found that the supercycle length is increasing at a rate of P_dot = 1.8 * 10^{-3}. Normal outbursts appear to be irregular, with typical occurrence times in the range 3.1 - 4.1 d. We detected a double-peaked structure of superhumps during superoutburst, with the secondary maximum becoming dominant near the end of the superoutburst. The mean superhump period observed during superoutbursts equals 0.066982(36) d, which is constant over the last two decades of observations. Based on the power spectrum analysis, the evaluation of the orbital period was problematic. We found two possible values: the first one, 0.06641(3) d, which is in agreement with previous studies and our O-C analysis (0.06646(2) d), and the second one, 0.06482(3) d, which is less likely. The evolutionary status of the object depends dramatically on the choice between these two values. A spectroscopic determination of the orbital period is needed. We updated available information on ER UMa-type stars and present a new set of their basic statistics. Thereby, we provide evidence that this class of stars is not uniform.Comment: Accepted for publication in MNRAS; 15 pages, 15 figures, 6 tables; typo correcte

MN Draconis - peculiar, active dwarf nova in the period gap

Context: We present results of an extensive world-wide observing campaign of MN Draconis. Aims: MN Draconis is a poorly known active dwarf nova in the period gap and is one of the only two known cases of period gap SU UMa objects showing the negative superhumps. Photometric behaviour of MN Draconis poses a challenge for existing models of the superhump and superoutburst mechanisms. Therefore, thorough investigation of peculiar systems, such as MN Draconis, is crucial for our understanding of evolution of the close binary stars. Methods: To measure fundamental parameters of the system, we collected photometric data in October 2009, June-September 2013 and June-December 2015. Analysis of the light curves, $O-C$ diagrams and power spectra was carried out. Results: During our three observational seasons we detected four superoutburts and several normal outbursts. Based on the two consecutive superoutbursts detected in 2015, the supercycle length was derived P_sc = 74 +/- 0.5 days and it has been increasing with a rate of P_dot = 3.3 x 10^(-3) during last twelve years. Based on the positive and negative superhumps we calculated the period excess epsilon = 5.6% +/- 0.1%, the period deficit epsilon_ = 2.5% +/- 0.6%, and in result, the orbital period P_orb = 0.0994(1) days (143.126 +/- 0.144 min). We updated the basic light curve parameters of MN Draconis. Conclusions: MN Draconis is the first discovered SU UMa system in the period gap with increasing supercycle length.Comment: 14 pages, 20 figures, 8 tables, accepted for publication in Astronomy and Astrophysic

Observation of the first gravitational microlensing event in a sparse stellar field : the Tago event

We report the observation of the first gravitational microlensing event in a sparse stellar field, involving the brightest (V=11.4 mag) andclosest (~ 1 kpc) source star to date. This event was discovered by an amateurastronomer, A. Tago, on 2006 October 31 as a transient brightening, by ~4.5 mag during a ~15 day period, of a normal A-type star (GSC 3656-1328) in the Cassiopeia constellation. Analysis of both spectroscopic observations and the light curve indicates that this event was caused by gravitational microlensing rather than an intrinsically variable star. Discovery of this single event over a 30 year period is roughly consistent with the expected microlensing rate for the whole sky down to V = 12 mag stars. However, the probability for finding events with such a high magnification (~ 50) is much smaller, by a factor ~1/50, which implies that the true event rate may be higher than expected. This discovery indicates the potential of all sky variability surveys, employing frequent sampling by telescopes with small apertures and wide fields of view, for finding such rare transient events, and using the observations to explore galactic disk structure and search for exo-planets.Comment: 13 pages, 2 tables, 3 figures, accepted by Ap

Large-scale gas disk around the radio galaxy Coma A

We present WSRT and VLA radio observations of the neutral hydrogen in the radio galaxy Coma A. We detect extended HI absorption against both radio lobes of Coma A, at distances of about 30 kpc from the centre. Coma A is the first radio galaxy in which HI is seen in absorption at such large distances from the nucleus. The match between the velocities of the neutral hydrogen and those of the extended ionized gas suggests that they are part of the same disk-like structure of at least 60 kpc in diameter. Most likely, this gas disk is partly ionised by the bulk motion of the radio lobes expanding into it. The gas mass of this disk is at least 10^9 Msun. The relatively regular structure of the gas disk suggests that a merger occurred involving at least one large gas-rich galaxy, at least a few times 10^8 yr ago.Comment: Accepted for publication in A&A, 8 pages, 8 figure

Design of Cationic Multi-Walled Carbon Nanotubes as Efficient siRNA Vectors for Lung Cancer Xenograft Eradication

Polo-Like Kinase (PLK1) has been identified as a potential target in cancer gene therapy via chemical or genetic inhibitory approaches. The biomedical applications of chemically functionalized carbon nanotubes (f-CNTs) in cancer therapy have been studied due to their ability to efficiently deliver siRNA intracellularly. In this study, we established the capacity of cationic MWNT-NH3+ to deliver the apoptotic siRNA against PLK1 (siPLK1) in Calu6 tumor xenografts by direct intratumoural injections. A direct comparison with cationic liposomes was made. This study validates the PLK1 gene as a potential target in cancer gene therapy including lung cancer, as demonstrated by the therapeutic efficacy of siPLK1:MWNT-NH3+ complexes and their ability to significantly improve animal survival. Biological analysis of the siPLK1:MWNT-NH3+ treated tumors by RT-PCR and Western blot, in addition to TUNEL staining confirmed the biological functionality of the siRNA intratumourally, suggesting that tumor eradication was due to PLK1 knockdown. Furthermore, by using a fluorescently labelled, non-coding siRNA sequence complexed with MWNT-NH3+, we established for the first time that the improved therapeutic efficacy observed in f-CNT-based siRNA delivery is directly proportional to the enhanced siRNA retention in the solid tumor and subsequent uptake by tumor cells after local administration in vivo

A comparative HST imaging study of the host galaxies of radio-quiet quasars, radio-loud quasars and radio galaxies: Paper I

We present the first results from a major HST WFPC2 imaging study aimed at providing the first statistically meaningful comparison of the morphologies, luminosities, scalelengths and colours of the host galaxies of radio-quiet quasars, radio-loud quasars, and radio galaxies. We describe the design of this study and present the images which have been obtained for the first half of our 33-source sample. We find that the hosts of all three classes of luminous AGN are massive elliptical galaxies, with scalelengths ~=10 kpc, and R-K colours consistent with mature stellar populations. Most importantly this is the the first unambiguous evidence that, just like radio-loud quasars, essentially all radio-quiet quasars brighter than M_R = -24 reside in massive ellipticals. This result removes the possibility that radio `loudness' is directly linked to host galaxy morphology, but is however in excellent accord with the black-hole/spheroid mass correlation recently highlighted by Magorrian et al. (1998). We apply the relations given by Magorrian et al. to infer the expected Eddington luminosity of the putative black hole at the centre of each of the spheroidal host galaxies we have uncovered. Comparison with the actual nuclear R-band luminosities suggests that the black holes in most of these galaxies are radiating at a few percent of the Eddington luminosity; the brightest host galaxies in our low-z sample are capable of hosting quasars with M_R = -28, comparable to the most luminous quasars at z = 3. Finally we discuss our host-derived black-hole masses in the context of the radio-luminosity:black-hole mass correlation recently uncovered for nearby galaxies by Franceschini et al. (1998), and the resulting implications for the physical origin of radio loudness.Comment: Submitted for publication in the Astrophysical Journal, 55 pages of latex, plus 12 postscript figures (Figures 1a-1s (greyscales of images and model fits, and Figures 2a-2g (luminosity profiles and model fits) can be downloaded from http://www.roe.ac.uk/astronomy/html/rjm1.shtml