146 research outputs found
Foreign Investment in the United States
Cord-F. Koening is a student in the Graduate Program, School of Business, Georgia Southern College
Recommendations for ICT use in Alzheimer's Disease assessment: Monaco CTAD expert meeting
International audienceAlzheimer disease (AD) and other related dementia represent a major challenge for health care systems within the aging population. It is therefore important to develop better instruments for assessing disease severity and disease progression to optimize patient's care and support to care provide rs, and also provide better tools for clinical research. In this area, Information and Communication Technologies (ICT) are of particular interest. Such techniques enable accurate and standardized assessments of patients' performance and actions in real time and real life situations. The aim of this article is to provide basic recommendation concerning the development and the use of ICT for Alzheimer's disease and related disorders. During he ICT and Mental Health workshop (CTAD meeting held in Monaco on the 30th October 2012) an expert panel was set up to prepare the first recommendations for the use of ICT in dementia research. The expert panel included geriatrician, epidemiologist, neurologist, psychiatrist, psychologist, ICT engineers, representatives from the industry and patient association. The recommendations are divided into three sections corresponding to 1/ the clinical targets of interest for the use of ICT, 2/ the cond itions, the type of sensors and the outputs (scores) that could be used and obtained, 3/ finally the last section concerns specifically the use of ICT within clinical trials
New record of Akashiwo sanguinea(Dinophyta) in the tropical estuarine waters of Northeastern Brazil (Western Atlantic)
Medium effects in high energy heavy-ion collisions
The change of hadron properties in dense matter based on various theoretical
approaches are reviewed. Incorporating these medium effects in the relativistic
transport model, which treats consistently the change of hadron masses and
energies in dense matter via the scalar and vector fields, heavy-ion collisions
at energies available from SIS/GSI, AGS/BNL, and SPS/CERN are studied. This
model is seen to provide satisfactory explanations for the observed enhancement
of kaon, antikaon, and antiproton yields as well as soft pions in the
transverse direction from the SIS experiments. In the AGS heavy-ion
experiments, it can account for the enhanced ratio, the difference
in the slope parameters of the and transverse kinetic energy
spectra, and the lower apparent temperature of antiprotons than that of
protons. This model also provides possible explanations for the observed
enhancement of low-mass dileptons, phi mesons, and antilambdas in heavy-ion
collisions at SPS energies. Furthermore, the change of hadron properties in hot
dense matter leads to new signatures of the quark-gluon plasma to hadronic
matter transition in future ultrarelativistic heavy-ion collisions at RHIC/BNL.Comment: RevTeX, 65 pages, including 25 postscript figures, invited topical
review for Journal of Physics G: Nuclear and Particle Physic
A comunidade microfitoplanctÎnica do Arquipélago de São Pedro e São Paulo (Atlùntico Norte-Equatorial): variação diurna e espacial
Raman spectroscopy of graphene and bilayer under biaxial strain: bubbles and balloons
In this letter we use graphene bubbles to study the Raman spectrum of
graphene under biaxial (e.g. isotropic) strain. Our Gruneisen parameters are in
excellent agreement with the theoretical values. Discrepancy in the previously
reported values is attributed to the interaction of graphene with the
substrate. Bilayer balloons (intentionally pressurized membranes) have been
used to avoid the effect of the substrate and to study the dependence of strain
on the inter-layer interactions.Comment: 14 pages, 4 figure
Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic AutoantibodyĂą Associated Vasculitis
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136726/1/art40034_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136726/2/art40034-sup-0002-suppinfo02.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136726/3/art40034-sup-0001-suppinfo01.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136726/4/art40034.pd
Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study
INTRODUCTION: High-risk non-muscle invasive bladder cancer (HRNMIBC) is a heterogeneous disease that can be difficult to predict. While around 25% of cancers progress to invasion and metastases, the remaining majority of tumours remain within the bladder. It is uncertain whether patients with HRNMIBC are better treated with intravesical maintenance BCG (mBCG) immunotherapy or primary radical cystectomy (RC). A definitive randomised controlled trial (RCT) is needed to compare these two different treatments but may be difficult to recruit to and has not been attempted to date. Before undertaking such an RCT, it is important to understand whether such a comparison is possible and how best to achieve it. METHODS AND ANALYSIS: BRAVO is a multi-centre, parallel-group, mixed-methods, individually randomised, controlled, feasibility study for patients with HRNMIBC. Participants will be randomised to receive either mBCG immunotherapy or RC. The primary objective is to assess the feasibility and acceptability of performing the definitive phase III trial via estimation of eligibility and recruitment rates, assessing uptake of allocated treatment and compliance with mBCG, determining quality-of-life questionnaire completion rates and exploring reasons expressed by patients for declining recruitment into the study. We aim to recruit 60 participants from six centres in the UK. Surgical trials with disparate treatment options find recruitment challenging from both the patient and clinician perspective. By building on the experiences of other similar trials through implementing a comprehensive training package aimed at clinicians to address these challenges (qualitative substudy), we hope that we can demonstrate that a phase III trial is feasible. ETHICS AND DISSEMINATION: The study has ethical approval (16/YH/0268). Findings will be made available to patients, clinicians, the funders and the National Health Service through traditional publishing and social media. TRIAL REGISTRATION NUMBER: ISRCTN12509361; Pre results
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