78 research outputs found

    The Sellarsian Fate of Mental Fictionalism

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    This chapter argues that mental fictionalism can only be a successful account of our ordinary folk-psychological practices if it can in some way preserve its original function, namely its explanatory aspect. A too strong commitment to the explanatory role moves fictionalism unacceptably close to the realist or eliminativist interpretation of folk psychology. To avoid this, fictionalists must degrade or dispense with this explanatory role. This motivation behind the fictionalist movement seems to be rather similar to that of Sellars when he came up with the Myth of Jones, his proto-theory of mental concepts. He was faced with the problem of preserving the explanatory status of mental concepts without turning them into proper theoretical entities. By introducing the Sellarsian proto-theory of concepts related to the mental and outlining its main points, this chapter aims to provide a critique of the two versions of mental fictionalism that are arguably the strongest: Adam Toon’s prop-oriented pretence theory and Tamás Demeter’s expressive storyism

    The Sellarsian fate of mental fictionalism

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    Summer Gifts from the Hive: Botanical Origin, Antioxidant Capacity, and Mineral Content of Hungarian Honeys

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    Although Hungary is one of the biggest honey producers in the EU, there is little information on diagnostic traits, nutritional value, and potential health benefits of the honeys produced in this Central European country. The aim of this study was to perform a complex analysis of eight Hungarian summer honeys, focusing on melissopalynology, antioxidant measurements with three different assays, and the macro- and microelement profile. Light-colored honey types included a multifloral honey and unifloral phacelia, milkweed, and linden honeys; dark-colored honeys were represented by unifloral goldenrod, sunflower, and chestnut honeys and a dark multifloral honey. Pollen analysis and sensory traits confirmed the botanical origin of each unifloral honey, while the dominance of Tilia- and Lamiaceae-pollen was observed in the light- and dark-colored multifloral honeys, respectively. The total reducing capacity (TRC) assay and the microelement content clearly separated the light- and dark-colored honeys. The oxygen radical absorbance capacity (ORAC) assay highlighted the strong antioxidant activity of linden honey, comparable to that of dark-colored honeys. Multivariate statistical analysis revealed correlations between antioxidant assays, color, and mineral content of honeys. The results contribute to establishing unique character sets for each honey type, aiding proper identification and quality control of these natural products

    Temporal instability of salience network activity in migraine with aura.

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    This study aims to investigate whether intra-network dynamic functional connectivity and causal interactions of the salience network is altered in the interictal term of migraine. 32 healthy controls, 37 migraineurs without aura and 20 migraineurs with aura were recruited. Participants underwent a T1-weighted scan and resting-state fMRI protocol inside a 1.5T MR scanner. We obtained average spatial maps of resting-state networks using group independent component analysis, which yielded subject-specific time series via a dual regression approach. Salience network ROIs (bilateral insulae and prefrontal cortices, dorsal anterior cingulate cortex) were obtained from the group average map via cluster-based thresholding. To describe intra-network connectivity, average and dynamic conditional correlation was calculated. Causal interactions between the default-mode, dorsal attention and salience network were characterised by spectral Granger's causality. Time-averaged correlation was lower between the right insula and prefrontal cortex in migraine without aura vs. with aura and healthy controls (p<0.038, p<0.037). Variance of dynamic conditional correlation was higher in migraine with aura vs. healthy controls and migraine with aura vs. without aura between the right insula and dorsal anterior cingulate cortex (p<0.011, p<0.026), and in migraine with aura vs. healthy controls between the dorsal anterior cingulate and left prefrontal cortex (p<0.021). Causality was weaker in the <0.05 Hz frequency range between the salience and dorsal attention networks in migraine with aura (p<0.032). Overall, migraineurs with aura exhibit more fluctuating connections in the salience network, which also affect network interactions, and could be connected to altered cortical excitability and increased sensory gain

    Continuous theta-burst stimulation over the dorsolateral prefrontal cortex inhibits improvement on a working memory task

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    Abstract Theta-burst stimulation (TBS) over the dorsolateral prefrontal cortex (DLPFC) may be more effective for modulating cortical excitability compared to standard repetitive transcranial magnetic stimulation. However, the impact of intermittent (iTBS) and continuous TBS (cTBS) on working memory (WM) is poorly studied. The aim of our study was to compare the effects of iTBS and cTBS on WM over the left and right DLPFC. iTBS, cTBS or sham stimulation was administered over the right and left hemisphere of fifty-one healthy human subjects. WM was assessed before and after TBS using the 1-back, 2-back, and 3-back tasks. We found classical practice effects in the iTBS and the sham group: WM performance improved following stimulation as measured by the discriminability index. However, this effect could not be observed in the cTBS group. We did not find any hemisphere-dependent effects, suggesting that the practice effect is not lateralized, and TBS affects WM performance in a comparable manner if administered either over the left or the right hemisphere. We propose that our findings represent a useful addition to the literature of TBS-induced effects on WM. Moreover, these results indicate the possibility of clarifying processes underlying WM performance changes by using non-invasive brain stimulation
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