127 research outputs found
L-Arginine Intake Effect on Adenine Nucleotide Metabolism in Rat Parenchymal and Reproductive Tissues
L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence. The aim of the present paper was to estimate the activity of the enzymes of adenine nucleotide metabolism: 5′-nucleotidase (5′-NU), adenosine deaminase (ADA), AMP deaminase, and xanthine oxidase (XO), during dietary intake of L-arginine for a period of four weeks of male Wistar rats. Adenosine concentration in tissues is maintained by the relative activities of the adenosine-producing enzyme, 5′-NU and the adenosine-degrading enzyme-ADA adenosine deaminase. Dietary L-arginine intake directed adenine nucleotide metabolism in liver, kidney, and testis tissue toward the activation of adenosine production, by increased 5′-NU activity and decreased ADA activity. Stimulation of adenosine accumulation could be of importance in mediating arginine antiatherosclerotic, vasoactive, immunomodulatory, and antioxidant effects. Assuming that the XO activity reflects the rate of purine catabolism in the cell, while the activity of AMP deaminase is of importance in ATP regeneration, reduced activity of XO, together with the increased AMP-deaminase activity, may suggest that adenine nucleotides are presumably directed to the ATP regenerating process during dietary L-arginine intake
Spectroscopy, Equation Of State And Monopole Percolation In Lattice QED With Two Flavors
Non-compact lattice QED with two flavors of light dynamical quarks is
simulated on lattices, and the chiral condensate, monopole density and
susceptibility and the meson masses are measured. Data from relatively high
statistics runs at relatively small bare fermion masses of 0.005, 0.01, 0.02
and 0.03 (lattice units) are presented. Three independent methods of data
analysis indicate that the critical point occurs at and that
the monopole condensation and chiral symmetry breaking transitions are
coincident. The monopole condensation data satisfies finite size scaling
hypotheses with critical indices compatible with four dimensional percolation.
The best chiral equation of state fit produces critical exponents
(, ) which deviate significantly from mean
field expectations. Data for the ratio of the sigma to pion masses produces an
estimate of the critical index in good agreement with chiral
condensate measurements. In the strong coupling phase the ratio of the meson
masses are ,
and , while on the weak coupling side of the
transition , ,
indicating the restoration of chiral symmetry.\footnote{\,^{}}{August 1992}Comment: 21 pages, 24 figures (not included
The management of anti-infective agents in intensive care units: the potential role of a ‘fast’ pharmacology
Assessment of the reliability of the serbian version of the sickness impact profile questionnaire in patients with chronic viral hepatitis
© 2015, Serbia Medical Society. All rights reserved. SUMMARY Introduction Health-related quality of life (HRQL) of chronic patients has been researched as the ultimate goal of modern treatment of chronic diseases to improve patients’ quality of life. Objective The objective was to assess the reliability of the Serbian version of the Sickness Impact Profile (SIP) questionnaire on the sample of patients with chronic viral hepatitis. Methods The research covered 102 patients with chronic hepatitis (47 type B and 55 type C). The assessment of the reliability of the SIP questionnaire was performed by testing the internal consistency of the questions by calculating the Cronbach’s alpha coefficient. The factor analysis was used to assess whether the grouping of the questions within dimensions matches the distribution of the questions in the original English version of the questionnaire administered to U.S. patient population. Results The Cronbach’s alpha coefficient for the entire questionnaire is 0.925, 0.869 for the physical dimension, and 0.857 for the psychosocial dimension. After running a factor analysis of the psychosocial dimension, “emotional instability” was extracted as the key factor, confirming the results of previous research. Compared with the English version of the questionnaire, the Cronbach’s alpha coefficient of the Serbian version does not diverge significantly, whereas the factor analysis confirms the classification of the questionnaire into two dimensions. Conclusion Our study has shown that the Serbian version of the SIP questionnaire is a reliable tool for assessing the HRQL of patients with chronic hepatitis B and C before starting treatment
Critical region of the finite temperature chiral transition
We study a Yukawa theory with spontaneous chiral symmetry breaking and with a
large number N of fermions near the finite temperature phase transition.
Critical properties in such a system can be described by the mean field theory
very close to the transition point. We show that the width of the region where
non-trivial critical behavior sets in is suppressed by a certain power of 1/N.
Our Monte Carlo simulations confirm these analytical results. We discuss
implications for the chiral phase transition in QCD.Comment: 18 page
Infrared Behaviour of Systems With Goldstone Bosons
We develop various complementary concepts and techniques for handling quantum
fluctuations of Goldstone bosons.We emphasise that one of the consequences of
the masslessness of Goldstone bosons is that the longitudinal fluctuations also
have a diverging susceptibility characterised by an anomalous dimension
in space-time dimensions .In these fluctuations diverge
logarithmically in the infrared region.We show the generality of this
phenomenon by providing three arguments based on i). Renormalization group
flows, ii). Ward identities, and iii). Schwinger-Dyson equations.We obtain an
explicit form for the generating functional of one-particle irreducible
vertices of the O(N) (non)--linear --models in the leading 1/N
approximation.We show that this incorporates all infrared behaviour correctly
both in linear and non-linear -- models. Our techniques provide an
alternative to chiral perturbation theory.Some consequences are discussed
briefly.Comment: 28 pages,2 Figs, a new section on some universal features of
multipion processes has been adde
Uv light impact on phthalates migration from children's toys into artificial saliva
Phthalates has been widely used in children?s toys as plastic plasticizers and softeners. Therefore, attention should be paid to plastic toys, especially those that children can put in their mouths. In this paper quantification of five phthalates: DMP, DnBP, BBP, DEHP and DnOP in plastic toys, as well as irradiation of toys with UV light was performed. After sample preparation and development of the liquid?liquid phthalate extraction method from artificial saliva phthalate quantitative determination using the GC?MS technique was performed. The mean recovery value for DEHP is 77.03?2.76 %. The determination of phthalate in the recipient models (artificial saliva and n-hexane) was performed after 6, 15 and 30 days of the migration test using the GC?MS technique. Based on the known mass % DEHP in the analyzed toys, the percentage of phthalate migration from each analyzed toy to the recipient model after 6, 15 and 30 days of the migration test was calculated. The results show that there is no significant migration of DEHP into artificial saliva, due to high polarity of the recipient (artificial saliva is polar), unlike n-hexane where the migration of DEHP is significant because it is a non-polar solvent
Duvan chvarci : product characterization and comparison between traditional and industrial production
Research Areas: Food Science & TechnologyThis research aimed to investigate and compare traditional products called “duvan chvarci” produced using pork meat and fat, originated from local households and industries. Physical and chemical analysis demonstrated differences among the examined products, mostly in total chloride content and TBARS values. Samples collected at local households showed finer color (higher lightness and yellowness) and sensory properties (rated as “extremely acceptable”), while industrial products were rated between “very acceptable” and “extremely acceptable“. Microbiological analysis exhibited that enterobacteria, coagulase-positive staphylococci, Salmonella spp., Shigella spp., and fungi were absent from all meat products. Dominant microbiota was identified as Lactobacillus spp. and Staphylococcus spp. All tested isolates showed γ-haemolysis on blood agar plates. Tested Staphylococcus spp. were sensitive to novobiocin while Lactobacillus isolates demonstrated sensitivity to ampicillin, chloramphenicol, clindamycin, erythromycin, tetracycline, gentamycin, and streptomycin. None of the tested isolates showed full resistance to antibiotics. Overall, results indicated that duvan chvarci is a microbiologically safe product and provided the initial evidence regarding the physical, chemical, technological, and sensory properties of this widely consumed product in the Balkans.info:eu-repo/semantics/publishedVersio
On the Logarithmic Triviality of Scalar Quantum Electrodynamics
Using finite size scaling and histogram methods we obtain numerical results
from lattice simulations indicating the logarithmic triviality of scalar
quantum electrodynamics, even when the bare gauge coupling is chosen large.
Simulations of the non-compact formulation of the lattice abelian Higgs model
with fixed length scalar fields on lattices with ranging from
through indicate a line of second order critical points.
Fluctuation-induced first order transitions are ruled out. Runs of over ten
million sweeps for each produce specific heat peaks which grow
logarithmically with and whose critical couplings shift with picking
out a correlation length exponent of consistent with mean field
theory. This behavior is qualitatively similar to that found in pure
.Comment: 9 page
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