571 research outputs found
On self-dual, doubly even codes of length 32
AbstractWe give a new proof for the theorem of Conway and Pless that there are exactly five binary linear self-dual doubly even extremal codes of length 32
Improvement of the phase regulation between two amplifiers feeding the inputs of the 3dB combiner in the ASDEX-Upgrade ICRH system
The present ICRF system at ASDEX Upgrade uses 3dB combiners to forward the combined power of a generator pair to a single line. Optimal output performance is achieved when the voltages at the two input lines of a combiner are equal in amplitude and the phase in quadrature. If this requirement is not met, a large amount of power is lost in the dummy loads of the combiner. To minimize losses, it is paramount to reach this phase relationship in a fast and stable way. The current phase regulation system is based on analog phase locked loops circuits. The main limitation of this system is the response time: several tens of milliseconds are needed to achieve a stable state. In order to get rid of the response time limitation of the current system, a new system is proposed based on a multi-channel direct digital synthesis device which is steered by a microcontroller and a software-based controller. The proposed system has been developed and successfully tested on a test-bench. The results show a remarkable improvement in the reduction of the response times. Other significant advantages provided by the new system include greater flexibility for frequency and phase settings, lower cost and a noticeable size reduction of the system
The Centrosomal Protein Pericentrin Identified at the Basal Body Complex of the Connecting Cilium in Mouse Photoreceptors
BACKGROUND: Pericentrin (Pcnt), a conserved protein of the pericentriolar material, serves as a multifunctional scaffold for numerous proteins and plays an important role in microtubule organization. Recent studies indicate that Pcnt mutations are associated with a range of diseases including primordial dwarfism and ciliopathies. To date, three Pcnt splice variants from orthologous genes in mice and humans are known. PRINCIPAL FINDINGS: We generated a specific Pcnt antiserum detecting all known Pcnt splice variants and examined the cellular and subcellular distribution of Pcnt in ciliated tissues of the mouse, the olfactory epithelium and the retina. For the first time, we identified Pcnt and its centrosomal interaction partners at the basal body complex of mouse retinal photoreceptors. Photoreceptors are morphologically and functionally subdivided into the light sensitive outer segment and the inner segment comprising the metabolic function of the cell. The two compartments are linked via a modified, specialized, non-motile cilium, the connecting cilium. Here, Pcnt colocalized with the whole protein machinery responsible for transport processes between the two compartments. Surprisingly, photoreceptors expressed a small Pcnt splice transcript - most likely a modified variant of Pcnt S - which was not present in receptor neurons of the olfactory epithelium. CONCLUSIONS: Our findings suggest distinct functional roles of several Pcnt variants in different ciliated tissues and sensory neurons, like the olfactory epithelium and the retina of the mouse. The individual patchwork of different Pcnt splice transcripts seems to reflect the complexity of Pcnt function, an assumption corroborated by the heterogeneous clinical manifestations associated with mutations in the Pcnt gene
Modeling extracellular field potentials and the frequency-filtering properties of extracellular space
Extracellular local field potentials (LFP) are usually modeled as arising
from a set of current sources embedded in a homogeneous extracellular medium.
Although this formalism can successfully model several properties of LFPs, it
does not account for their frequency-dependent attenuation with distance, a
property essential to correctly model extracellular spikes. Here we derive
expressions for the extracellular potential that include this
frequency-dependent attenuation. We first show that, if the extracellular
conductivity is non-homogeneous, there is induction of non-homogeneous charge
densities which may result in a low-pass filter. We next derive a simplified
model consisting of a punctual (or spherical) current source with
spherically-symmetric conductivity/permittivity gradients around the source. We
analyze the effect of different radial profiles of conductivity and
permittivity on the frequency-filtering behavior of this model. We show that
this simple model generally displays low-pass filtering behavior, in which fast
electrical events (such as Na-mediated action potentials) attenuate very
steeply with distance, while slower (K-mediated) events propagate over
larger distances in extracellular space, in qualitative agreement with
experimental observations. This simple model can be used to obtain
frequency-dependent extracellular field potentials without taking into account
explicitly the complex folding of extracellular space.Comment: text (LaTeX), 6 figs. (ps
Musikgeschichte in Mittel- und Osteuropa: Mitteilungen der internationalen Arbeitsgemeinschaft an der Universität Leipzig : in Zusammenarbeit mit den Mitgliedern der internationalen Arbeitsgemeinschaft für die Musikgeschichte in Mittel- und Osteuropa an der Universität Leipzig
Als 'Mitteilungen' dokumentieren die einzelnen Hefte die Zusammenarbeit von Musikwissenschaftlern aus den betroffenen Gebieten seit 1997
Beethoven-Rezeption in Mittel- und Osteuropa: Bericht über die Internationale Musikwissenschaftliche Konferenz vom 22. bis 26. Oktober 2014 in Leipzig
Die Internationale Musikwissenschaftliche Konferenz vom 23. bis 25. Oktober
2014 am Institut für Musikwissenschaft der Universität Leipzig hatte
die „Beethoven-Rezeption in Mittel- und Osteuropa“ zum Thema. Dieses
besitzt zentrale Bedeutung für das Verständnis der Musikgeschichte zwischen
Ost- und Westeuropa und setzt die lange Zusammenarbeit der Arbeitsgemeinschaft
für die Musikgeschichte in Mittel- und Osteuropa fort.
Die Beethoven-Rezeption bezeichnet eine in der Musikgeschichte des 19.
und 20. Jahrhunderts zentrale Erscheinung, die für die Ausbreitung der
bürgerlichen Musikkultur in Europa maßgebend war. Zu fragen ist, wie
und zu welcher Zeit sich Beethovens Musik im Konzertleben verschiedener
Regionen etabliert hat, wie das Phänomen Beethoven von Komponisten
kompositorisch bewältigt wurde und vor allem, welche Vorstellungen
und Ideale mit seiner Musik zu bestimmten Zeiten an bestimmten Orten
ganz konkret verbunden wurden. Die Mozart-Rezeption war bereits 1996 in
Chemnitz Thema einer der frühen Tagungen der Arbeitsgemeinschaft für
die Musikgeschichte in Mittel- und Osteuropa, die Schumann-Rezeption
wurde 2010 und im Jahr 2013 die Wagner-Rezeption auf unseren Leipziger
Konferenzen thematisiert. Beethoven bildet in dieser Hinsicht noch
ein sträflich vernachlässigtes Thema. Dieses Desideratum der Forschung ist
aufzuarbeiten, dazu leistet der vorliegende Tagungsbericht einen bescheidenen
Beitrag (leider sind nicht alle Vorträge zum Druck freigegeben worden).
Er soll auch zu weiteren Forschungen anregen
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