112 research outputs found

    Values and believes parental: theoretical considerations

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    O contexto cultural permite o acúmulo de informações dentro de um grupo que se reflete em crenças e práticas. Compreender a relação entre a natureza humana e cultura é uma questão complexa e necessária para a compreensão do comportamento. Ampliar pesquisas enfocando a complexa relação entre o biológico e o social promove um melhor entendimento sobre o desenvolvimento, o que significa que estudar crenças e práticas permite entender melhor a relação entre o homem e a cultura e, conseqüentemente, compreender melhor o comportamento humano. A importância do estudo de crenças parentais para a compreensão do desenvolvimento humano mostra que os sistemas de crenças parentais têm emergido como um campo de estudo relevante para a compreensão do desenvolvimento por estar diretamente vinculado ao estilo de cuidado dispensado à criança.The cultural context allows the gathering of information inside a group, and this is reflected on beliefs and practices. To understand the relationship between human nature and culture is a complex and necessary task for the comprehension of behavior. The conduction of more research studies focusing on the complex relationship between the social and the biological promotes a better understanding of development, which means that the study of beliefs and practices allows us to deepen our understanding of the relationship between men and culture and, consequently, to better understand human behavior. Thus, the study of parental beliefs is important to the comprehension of human development because it is directly linked with the style of child care

    Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry

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    BACKGROUND: Three-dimensional (3D) imaging mass spectrometry (MS) is an analytical chemistry technique for the 3D molecular analysis of a tissue specimen, entire organ, or microbial colonies on an agar plate. 3D-imaging MS has unique advantages over existing 3D imaging techniques, offers novel perspectives for understanding the spatial organization of biological processes, and has growing potential to be introduced into routine use in both biology and medicine. Owing to the sheer quantity of data generated, the visualization, analysis, and interpretation of 3D imaging MS data remain a significant challenge. Bioinformatics research in this field is hampered by the lack of publicly available benchmark datasets needed to evaluate and compare algorithms. FINDINGS: High-quality 3D imaging MS datasets from different biological systems at several labs were acquired, supplied with overview images and scripts demonstrating how to read them, and deposited into MetaboLights, an open repository for metabolomics data. 3D imaging MS data were collected from five samples using two types of 3D imaging MS. 3D matrix-assisted laser desorption/ionization imaging (MALDI) MS data were collected from murine pancreas, murine kidney, human oral squamous cell carcinoma, and interacting microbial colonies cultured in Petri dishes. 3D desorption electrospray ionization (DESI) imaging MS data were collected from a human colorectal adenocarcinoma. CONCLUSIONS: With the aim to stimulate computational research in the field of computational 3D imaging MS, selected high-quality 3D imaging MS datasets are provided that could be used by algorithm developers as benchmark datasets
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