Family Offices and Institutional Change in Europe: A Comparative Analysis

This study analyzes the changes in the institutional contexts of family offices in four major European economies. Drawing on institutional theory and considering capitalist varieties, it uses a qualitative content analysis of the newspaper coverage in the UK, Switzerland, Germany, and France from 2000 to 2018. The findings reveal significant changes in the regulatory environment in most countries, few changes in the normative dimension, and an increase in critical articles over time. They add to the literature on institutional change in and across countries by identifying new types of drivers of change in the context of family offices

How does entrepreneurship education affect employability? Insights from UK higher education

Purpose: The purpose of this study is to examine the underexplored link between entrepreneurship education (EE) and graduate employability in the higher education (HE) sector in the United Kingdom (UK).Design/methodology/approach: The study draws on a thematic content analysis of semi-structured interviews with 45 professionals in UK HE, representing the “supply” side of EE.Findings: The findings demonstrate a unidirectional link between EE and employability outcomes. This link is affected by societal, stakeholder-related, and teaching and learning-related factors.Research limitations/implications: Although the value of universities’ initiatives connecting EE and employability for economic development is emphasized, the study does not provide direct empirical evidence for this effect. Macroeconomic research is needed.Practical implications: EE and employability would benefit from knowledge exchange between universities’ stakeholders and a broader understanding of what constitutes a valuable graduate outcome.Social implications: The study reveals the benefits of EE on a micro level. Participation in EE supports the connection between individual investments in HE and employability.Originality/value: Based on human capital theory, many policymakers regard EE as a vehicle through which the relationship between investments in HE and career success on a micro level and economic growth on a macro level can be nurtured. Challenging this logic, the study highlights the potential of institutional theory to explain a contextualization of the link between EE and employability on a national level

a methodology for understanding path dependence and path creation

Although an increasing number of studies of technological, institutional and organizational change refer to the concepts of path dependence and path creation, few attempts have been made to consider these concepts explicitly in their methodological accounts. This paper addresses this gap and contributes to the literature by developing a comprehensive methodology that originates from the concepts of path dependence and path creation – path constitution analysis (PCA) – and allows for the integration of multi-actor constellations on multiple levels of analysis within a process perspective. Based upon a longitudinal case study in the field of semiconductors, we illustrate PCA ‘in action’ as a template for other researchers and critically examine its adequacy. We conclude with implications for further path-oriented inquiries

OpenMS - A Framework for Quantitative HPLC/MS-Based Proteomics

In the talk we describe the freely available software library OpenMS which is currently under development at the Freie Universität Berlin and the Eberhardt-Karls Universität Tübingen. We give an overview of the goals and problems in differential proteomics with HPLC and then describe in detail the implemented approaches for signal processing, peak detection and data reduction currently employed in OpenMS. After this we describe methods to identify the differential expression of peptides and propose strategies to avoid MS/MS identification of peptides of interest. We give an overview of the capabilities and design principles of OpenMS and demonstrate its ease of use. Finally we describe projects in which OpenMS will be or was already deployed and thereby demonstrate its versatility

Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial

Background: Given the global increase in the aging population and age-related diseases, the promotion of healthy aging is one of the most crucial public health issues. This trial aims to contribute to the establishment of effective approaches to promote cognitive and brain health in older individuals with subjective cognitive decline (SCD). Presence of SCD is known to increase the risk of objective cognitive decline and progression to dementia due to Alzheimer’s disease. Therefore, it is our primary goal to determine whether spermidine supplementation has a positive impact on memory performance in this at-risk group, as compared with placebo. The secondary goal is to examine the effects of spermidine intake on other neuropsychological, behavioral, and physiological parameters. Methods: The SmartAge trial is a monocentric, randomized, double-blind, placebo-controlled phase IIb trial. The study will investigate 12 months of intervention with spermidine-based nutritional supplementation (target intervention) compared with 12months of placebo intake (control intervention). We plan to recruit 100 cognitively normal older individuals with SCD from memory clinics, neurologists and general practitioners in private practice, and the general population. Participants will be allocated to one of the two study arms using blockwise randomization stratified by age and sex with a 1:1 allocation ratio. The primary outcome is the change in memory performance between baseline and post-intervention visits (12 months after baseline). Secondary outcomes include the change in memory performance from baseline to follow-up assessment (18months after baseline), as well as changes in neurocognitive, behavioral, and physiological parameters (including blood and neuroimaging biomarkers), assessed at baseline and post-intervention. Discussion: The SmartAge trial aims to provide evidence of the impact of spermidine supplementation on memory performance in older individuals with SCD. In addition, we will identify possible neurophysiological mechanisms of action underlying the anticipated cognitive benefits. Overall, this trial will contribute to the establishment of nutrition intervention in the prevention of Alzheimer’s disease

Seasonal variations of hydrographic parameters off the Sudanese coast of the Red Sea, 2009–2015

© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Regional Studies in Marine Science 18 (2018): 1-10, doi:10.1016/j.rsma.2017.12.004.The variations of temperature and salinity in the Sudanese coastal zone of the Red Sea are studied for the first time using measurements acquired from survey cruises during 2009–2013 and from a mooring during 2014–2015. The measurements show that temperature and salinity variability above the permanent pycnocline is dominated by seasonal signals, similar in character to seasonal temperature and salinity oscillations observed further north on the eastern side of the Red Sea. Using estimates of heat flux, circulation and horizontal temperature/salinity gradients derived from a number of sources, we determined that the observed seasonal signals of temperature and salinity are not the product of local heat and mass flux alone, but are also due to alongshore advection of waters with spatially varying temperature and salinity. As the temperature and salinity gradients, characterized by warmer and less saline water to the south, exhibit little seasonal variation, the seasonal salinity and temperature variations are closely linked to an observed seasonal oscillation in the along-shore flow, which also has a mean northward component. We find that the inclusion of the advection terms in the heat and mass balance has two principal effects on the computed temperature and salinity series. One is that the steady influx of warmer and less saline water from the south counteracts the long-term trend of declining temperatures and rising salinities computed with only the local surface flux terms, and produces a long-term steady state in temperature and salinity. The second effect is produced by the seasonal alongshore velocity oscillation and most profoundly affects the computed salinity, which shows no seasonal signal without the inclusion of the advective term. In both the observations and computed results, the seasonal salinity signal lags that of temperature by roughly 3 months.The SPS surveys were funded by the Norwegian Norad’s Program for Master Studies and organized by IMR–RSU in Port Sudan. The central Red Sea mooring data were acquired as part of a WHOI–KAUST collaboration funded by Award Nos. USA00001, USA00002, and KSA00011 to the WHOI by the KAUST in the Kingdom of Saudi Arabia. The work of I. Skjelvan and A.M. Omar was partly supported by the Research Council of Norway through the MIMT Center for Research-based Innovation. This work is part of a Ph.D. project at GFI–UiB funded by the Norwegian Quota program

Arctic fishes in the Barents Sea 2004-2015: Changes in abundance and distribution

The Barents Sea is one of nine shelf ecosystem survey bordering the Arctic Basin. The Arctic region is warming faster than the rest of the world. In the Barents Sea the years since 2000 were the warmest since the onset of regular measurements (1900, Bochkov 1982, ICES 2016) and paleo-records based on foraminifera even suggest that the Atlantic Water flowing into to the Barents Sea area was at its warmest for the last 2000 years (Spielhagen et al. 2011). As a result the extent of Arctic Water with sub-zero temperatures and sea ice is shrinking in the Barents Sea (e.g. ICES 2016). The changes in hydrographic conditions change the conditions for the poorly known Arctic fish fauna in the region. Here we present for the first time results on trends in abundance and distribution of demersal Arctic fishes in the northern Barents Sea.publishedVersio

Different mechanisms of Arctic first-year sea-ice ridge consolidation observed during the MOSAiC expedition

Sea-ice ridges constitute a large fraction of the ice volume in the Arctic Ocean, yet we know little about the evolution of these ice masses. Here we examine the thermal and morphological evolution of an Arctic firstyear sea-ice ridge, from its formation to advanced melt. Initially the mean keel depth was 5.6 m and mean sail height was 0.7 m. The initial rubble macroporosity (fraction of seawater filled voids) was estimated at 29% from ice drilling and 43%–46% from buoy temperature. From January until mid-April, the ridge consolidated slowly by heat loss to the atmosphere and the total consolidated layer growth during this phase was 0.7 m. From mid-April to mid-June, there was a sudden increase of ridge consolidation rate despite no increase in conductive heat flux. We surmise this change was related to decreased macroporosity due to transport of snow-slush to the ridge keel rubble via adjacent open leads. In this period, the mean thickness of the consolidated layer increased by 2.1 m. At the peak of melt in June–July we suggest that the consolidation was related to the refreezing of surface snow and ice meltwater and of ridge keel meltwater (the latter only about 15% of total consolidation). We used the morphology parameters of the ridge to calculate its hydrostatic equilibrium and obtained a more accurate estimate of the actual consolidation of the keel, correcting from 2.2 m to 2.8 m for average keel consolidation. This approach also allowed us to estimate that the average keel melt of 0.3 m, in June–July, was accompanied by a decrease in ridge draft of 0.9 m. An ice mass balance buoy in the ridge indicated total consolidation of 2.8 m, of which 2.1 m was related to the rapid mode of consolidation from April to June. By mid-June, consolidation resulted in a drastic decrease of the macroporosity of the interior of keel while the flanks had little or no change in macroporosity. These results are important to understanding the role of ridge keels as meltwater sources and sinks and as sanctuary for ice-associated organisms in Arctic pack ice

Arctic fishes in the Barents Sea 2004-2015: Changes in abundance and distribution

The Barents Sea is one of nine shelf ecosystem survey bordering the Arctic Basin. The Arctic region is warming faster than the rest of the world. In the Barents Sea the years since 2000 were the warmest since the onset of regular measurements (1900, Bochkov 1982, ICES 2016) and paleo-records based on foraminifera even suggest that the Atlantic Water flowing into to the Barents Sea area was at its warmest for the last 2000 years (Spielhagen et al. 2011). As a result the extent of Arctic Water with sub-zero temperatures and sea ice is shrinking in the Barents Sea (e.g. ICES 2016). The changes in hydrographic conditions change the conditions for the poorly known Arctic fish fauna in the region. Here we present for the first time results on trends in abundance and distribution of demersal Arctic fishes in the northern Barents Sea.publishedVersio