Managing irrigation under pressure: how supply chain demands and environmental objectives drive imbalance in agricultural resilience to water shortages

Food production systems worldwide are increasingly exposed to water shortage shocks. Social-ecological resilience theory provides insights into the qualities which confer production systems with the capacity to absorb shocks and persist, undertake adaptations and ultimately achieve desirable transformations. Combining findings from the analysis of a set of 15 semi-structured interviews and 92 survey responses from growers in the UK, this paper uses resilience theory to explore the factors affecting exposure to the risk of water shortages, and management responses, within outdoor field vegetable production systems that depend on supplemental irrigation. The findings confirm that growers predominantly aim to build resilience by seeking to maintain a buffer or ‘headroom’ in their water resources to minimise the possibility that a shortage will disrupt their output of marketable produce and/ or lead to financial loss. This buffering strategy confers robustness by increasing system redundancy (availability of spare resources). But building-in redundancy conflicts with regulatory and supply chain pressures to maximise water and production efficiency respectively. Whilst stability of supply to consumers is, for the most-part, achieved, the discrepant pursuits of robustness and efficiency lock agricultural systems into increasingly rigid production and sales pathways, limiting capacities for adaptation and transformation - dimensions of resilience which permit successful system evolution in the context of more extreme shocks and stresse

‘I think this is where this lovely word “sustainability” comes in’: Fruit and vegetable growers' narratives concerning the regulation of environmental water use for food production

This article concerns UK commercial fruit and vegetable growers’ narratives regarding the sustainability of water use for food production. In it we explore their perspectives on efforts by regulators to limit agricultural withdrawals of water from the natural environment in line with EU Water Framework Directive objectives, alongside their views on retailer sustainability commitments. Discourse analysis is used to investigate how the growers contested restrictive regulation, constructed their identities, portrayed other supply chain stakeholders, and conveyed their social relations with them. Using Erving Goffman's theory of frontstage and backstage performances, the implications for the growers’ water management decisions and their internalisation of sustainability agendas for water are examined. Whilst the growers gave accounts of purposely misrepresenting their water withdrawal practices and their discourse illustrated significant polarisation between environmental and agricultural interests, their underlying commitment to environmental sustainability was ambivalent, with both anti and pro-environmental attitudes expressed. The growers also frequently gave critiques of superficial sustainability in fresh produce supply chains. We argue that, given contemporary shifting definitions of agricultural identities, settings in which their construction is negotiated can provide windows of opportunity for conventional growers to engage in genuine pro-environmental performances that may deepen their assimilation of environmental goals and commitment to sustainable water use.Biotechnology and Biological Sciences Research Council (BBSRC): BB/N020499/1. ESRC; NERC; Scottish Governmen

Resilience of primary food production to a changing climate: on-farm responses to water-related risks

Water is a fundamental component in primary food production, whether it be rainfall, irrigation used to water crops, or for supplying drinking water for animals, while the amount of water in the soil determines it capacity to support machinery and animals. We identify that UK agriculture is exposed to five main water-related risks: agricultural drought, scarcity of water resources, restrictions on the right to abstract water, excess soil water, and inundation. Projected milder, wetter winters and hotter, drier summers by the end of the century will change the frequency, persistence, or severity of each of these risks. This paper critically reviews and synthesizes the scientific literature on the impact of these risks on primary food production and the technological and managerial strategies employed to build resilience to these changing risks. At the farm scale, the emphasis has been on strategies to build robustness to reduce the impact of a water-related risk. However, collaborative partnerships allow for a more optimal allocation of water during times of scarcity. Enhancing cross-scale interactions, learning opportunities, and catchment-scale autonomy will be key to ensuring the agricultural system can build adaptive and transformational capacit

Surface Charge Control of Quantum Dot Blinking

A characteristic property of colloidal semiconductor nanocrystal quantum dots (QDs) is their emission intermittency. Although a unifying theory of QD photoprocesses remains elusive, the importance of charged states is clear. We now report a new approach to directly study the role of surface charge on QD emission by adding metal ions to individual, core-only QDs immobilized in aqueous solution in an agarose gel. The CdTe QDs show very stable emission in the absence of metal ions but a dramatic and reversible increase in blinking due to the presence of trivalent metal ions. Our results support a charge-separation model, in which the major blinking pathway is the surface trapping of electrons; transiently bound metal ions close to the QD surface enhance this process

Facilitating primary care non-antiretroviral drug prescribing in people living with HIV: the ‘THINK ARV’ initiative

Objectives: Older people living with HIV (PLWH) have higher rates of multimorbidity, polypharmacy and an associated increased risk of potential drug–drug interactions (DDIs). We describe the development, implementation and evaluation of an intervention to increase community prescribers’ access to specialist prescribing advice. Methods: Phase One: a survey evaluating General Practitioners’ (GPs’) knowledge of, and confidence detecting DDIs affecting PLWH, was circulated to eight General Practices in one UK city. Phase Two: co-production was used to develop the THINK ARV intervention for prescribers in city-wide General Practices: a dedicated mobile phone and e-mail advice service staffed by HIV specialist pharmacists. Queries were audited for 6 months pre- and post-intervention. A user-satisfaction survey was emailed to enquirers. Results: Phase One: 42 GPs responded, of whom 62% requested further support identifying DDIs among PLWH. Phase Two: the number of queries received increased from 25 (6 months before ‘THINK ARV’ launch) to 63 in the following 6 months (152% increase). 94% of the queries were specifically about DDIs. Conclusions: Increasing community prescribers’ access to specialist telephone and e-mail advice resulted in increased awareness and detection of DDIs. Similar interventions could be embedded within different healthcare settings to optimise medicines and avoid potential patient harm

Proceedings of Abstracts, School of Physics, Engineering and Computer Science Research Conference 2022

© 2022 The Author(s). This is an open-access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For further details please see https://creativecommons.org/licenses/by/4.0/. Plenary by Prof. Timothy Foat, ‘Indoor dispersion at Dstl and its recent application to COVID-19 transmission’ is © Crown copyright (2022), Dstl. This material is licensed under the terms of the Open Government Licence except where otherwise stated. To view this licence, visit http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: [email protected] present proceedings record the abstracts submitted and accepted for presentation at SPECS 2022, the second edition of the School of Physics, Engineering and Computer Science Research Conference that took place online, the 12th April 2022

Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial

Objective: The HOME BP (Home and Online Management and Evaluation of Blood Pressure) trial aimed to test a digital intervention for hypertension management in primary care by combining self-monitoring of blood pressure with guided self-management. Design: Unmasked randomised controlled trial with automated ascertainment of primary endpoint. Setting: 76 general practices in the United Kingdom. Participants: 622 people with treated but poorly controlled hypertension (>140/90 mm Hg) and access to the internet. Interventions: Participants were randomised by using a minimisation algorithm to self-monitoring of blood pressure with a digital intervention (305 participants) or usual care (routine hypertension care, with appointments and drug changes made at the discretion of the general practitioner; 317 participants). The digital intervention provided feedback of blood pressure results to patients and professionals with optional lifestyle advice and motivational support. Target blood pressure for hypertension, diabetes, and people aged 80 or older followed UK national guidelines. Main outcome measures: The primary outcome was the difference in systolic blood pressure (mean of second and third readings) after one year, adjusted for baseline blood pressure, blood pressure target, age, and practice, with multiple imputation for missing values. Results: After one year, data were available from 552 participants (88.6%) with imputation for the remaining 70 participants (11.4%). Mean blood pressure dropped from 151.7/86.4 to 138.4/80.2 mm Hg in the intervention group and from 151.6/85.3 to 141.8/79.8 mm Hg in the usual care group, giving a mean difference in systolic blood pressure of −3.4 mm Hg (95% confidence interval −6.1 to −0.8 mm Hg) and a mean difference in diastolic blood pressure of −0.5 mm Hg (−1.9 to 0.9 mm Hg). Results were comparable in the complete case analysis and adverse effects were similar between groups. Within trial costs showed an incremental cost effectiveness ratio of £11 ($15, €12; 95% confidence interval £6 to £29) per mm Hg reduction. Conclusions: The HOME BP digital intervention for the management of hypertension by using self-monitored blood pressure led to better control of systolic blood pressure after one year than usual care, with low incremental costs. Implementation in primary care will require integration into clinical workflows and consideration of people who are digitally excluded. Trial registration: ISRCTN13790648

Probing the Inconsistencies of State Feticide and Abortion Law

This paper serves as an analysis of both intrastate and interstate statutory inconsistencies between feticide and abortion law within the thirty-eight American states with criminal feticide laws on record. By reviewing the particulars of each statute, it becomes apparent that there are severe and widespread contradictions between the implications of feticide and abortion laws within each state, as well disparities amongst the states themselves. I will argue that these inconsistencies in protection for unborn life are nothing new in American law. The United States has struggled since its inception to establish stable legislation regarding the protection of the unborn. This historic struggle translates over to the country’s current problem of how to regulate the protection of unborn life. The inconsistencies pose a threat to either one of two groups: the laws treat those convicted of feticide far too harshly, thus violating their right to be free from cruel and unusual punishment, or the laws neglect the inherent value of unborn life by permitting their death in cases of abortion. In either case, it is vital that the American government thoughtfully examine these contradictions and bring about a movement to remedy this violation of fundamental rights

Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.

Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies identified the adult neural stem cells and found important links between adult neurogenesis and plasticity, behavior, and disease. However, whether new neurons are produced in the human dentate gyrus (DG) during healthy aging is still debated. We and others readily observe proliferating neural progenitors in the infant hippocampus near immature cells expressing doublecortin (DCX), but the number of such cells decreases in children and few, if any, are present in adults. Recent investigations using dual antigen retrieval find many cells stained by DCX antibodies in adult human DG. This has been interpreted as evidence for high rates of adult neurogenesis, even at older ages. However, most of these DCX-labeled cells have mature morphology. Furthermore, studies in the adult human DG have not found a germinal region containing dividing progenitor cells. In this Dual Perspectives article, we show that dual antigen retrieval is not required for the detection of DCX in multiple human brain regions of infants or adults. We review prior studies and present new data showing that DCX is not uniquely expressed by newly born neurons: DCX is present in adult amygdala, entorhinal and parahippocampal cortex neurons despite being absent in the neighboring DG. Analysis of available RNA-sequencing datasets supports the view that DG neurogenesis is rare or absent in the adult human brain. To resolve the conflicting interpretations in humans, it is necessary to identify and visualize dividing neuronal precursors or develop new methods to evaluate the age of a neuron at the single-cell level