Application of Soft Computing Technologies toward Assessment and Skills Development

Schools and universities face multiple challenges when they target initiating or expanding undergraduate programs. Education has traditionally utilized a teacher-centered educational and assessment approach. Only few attempts exist to involve objective feedback and non-traditional assessment methods and technologies to improve the processes of teaching, learning, and education in general. This paper addresses a novel objective multi-parameter assessment methodology based on Soft computing technology to discover the effect of students’ groupings by exploiting the interrelationships between the grades the students received for their laboratory subjects and the grade they obtained in the university enrolment exam. The research results allow for exploring non-desirable discordant teaching and assessment practices for individuals or groups. In addition, the results obtained illustrate opportunities to focus on the individual student during the education process and determine adaptive teaching strategies based on the particular level of knowledge and experience. Toward these results statistical and Soft computing models implementing Unsupervised Neural and Exploratory Projection Techniques have been applied to carry on the objective assessment of the students’ skills development during the entire higher education period. Empirical verification of the proposed assessment model is performed in a real environment, where a case study is defined, and analysed. The real data set to validate the performance of the proposed approach has been collected at the School of Dentistry of the Complutense University of Madrid

Salamanca, Spain, September 11th-13th, 2013 Proceedings

This volume of Advances in Intelligent and Soft Computing contains accepted papers presented at SOCO 2013, CISIS 2013 and ICEUTE 2013, all conferences held in the beautiful and historic city of Salamanca (Spain), in September 2013. Soft computing represents a collection or set of computational techniques in machine learning, computer science and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena. After a through peer-review process, the 8th SOCO 2013 International Program Committee selected 40 papers which are published in these conference proceedings, and represents an acceptance rate of 41%. In this relevant edition a special emphasis was put on the organization of special sessions. Four special sessions were organized related to relevant topics as: Systems, Man, and Cybernetics, Data Mining for Industrial and Environmental Applications, Soft Computing Methods in Bioinformatics, and Soft Computing Methods, Modelling and Simulation in Electrical Engineer. The aim of the 6th CISIS 2013 conference is to offer a meeting opportunity for academic and industry-related researchers belonging to the various, vast communities of Computational Intelligence, Information Security, and Data Mining. The need for intelligent, flexible behaviour by large, complex systems, especially in mission-critical domains, is intended to be the catalyst and the aggregation stimulus for the overall event. After a through peer-review process, the CISIS 2013 International Program Committee selected 23 papers which are published in these conference proceedings achieving an acceptance rate of 39%. In the case of 4th ICEUTE 2013, the International Program Committee selected 11 papers which are published in these conference proceedings. The selection of papers was extremely rigorous in order to maintain the high quality of the conference and we would like to thank the members of the Program Committees for their hard work in the reviewing process. This is a crucial process to the creation of a high standard conference and the SOCO, CISIS and ICEUTE conferences would not exist without their help

Global Retinoblastoma Presentation and Analysis by National Income Level.

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs

The global retinoblastoma outcome study : a prospective, cluster-based analysis of 4064 patients from 149 countries

DATA SHARING : The study data will become available online once all analyses are complete.BACKGROUND : Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. METHODS : We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1, 2017, and Dec 31, 2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. FINDINGS : The cohort included 4064 children from 149 countries. The median age at diagnosis was 23·2 months (IQR 11·0–36·5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0·8%) of 636 children from high-income countries, 55 (5·4%) of 1027 children from upper-middle-income countries, 342 (19·7%) of 1738 children from lower-middle-income countries, and 196 (42·9%) of 457 children from low-income countries. Enucleation surgery was available for all children and intravenous chemotherapy was available for 4014 (98·8%) of 4064 children. The 3-year survival rate was 99·5% (95% CI 98·8–100·0) for children from high-income countries, 91·2% (89·5–93·0) for children from upper-middle-income countries, 80·3% (78·3–82·3) for children from lower-middle-income countries, and 57·3% (52·1-63·0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16·67; 95% CI 4·76–50·00), cT4 advanced tumour compared to cT1 (8·98; 4·44–18·18), and older age at diagnosis in children up to 3 years (1·38 per year; 1·23–1·56). For children aged 3–7 years, the mortality risk decreased slightly (p=0·0104 for the change in slope). INTERPRETATION : This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes.The Queen Elizabeth Diamond Jubilee Trust and the Wellcome Trust.https://www.thelancet.com/journals/langlo/homeam2023Paediatrics and Child Healt

Conceptual Framework for the Use of the Service-oriented Architecture-Approach in the Digital Preservation: Paper - iPRES 2008 - London

This paper presents a conceptual framework for the use of the SOA1-approach in the digital preservation. The focus of this work reflects the service composition part within the SOA service concept. Previously released approaches have been separately using process-oriented models to describe the behaviour of services, and structure composition models to represent service interactions. In this paper, the authors attempt to combine the even mentioned disjunctive models to obtain a comprehensive model, which represents both, the structure and the behaviour of the services. For this purpose, the novel SCA2-BPEL3 serves as basis for the implementation in a future-oriented SOA-compliant digital preservation software system. The SCA-model specifies the architecture of the intended system, while the BPEL-model indicates the behavior of each service, which is defined in the SCA-model. We can conclude that the SCA-BPEL approach is well-suited for building a scalable, adaptable and service-oriented software system. The knowledge gained from the conceptual framework will serve as a basis for future digital preservation developments