3,563 research outputs found
Rotation Curves of Spiral Galaxies and Large Scale Structure of Universe under Generalized Einstein Action
We consider an addition of the term which is a square of the scalar curvature
to the Einstein-Hilbert action. Under this generalized action, we attempt to
explain i) the flat rotation curves observed in spiral galaxies, which is
usually attributed to the existence of dark matter, and ii) the contradicting
observations of uniform cosmic microwave background and non-uniform galaxy
distributions against redshift. For the former, we attain the flatness of
velocities, although the magnitudes remain about half of the observations. For
the latter, we obtain a solution with oscillating Hubble parameter under
uniform mass distributions. This solution leads to several peaks of galaxy
number counts as a function of redshift with the first peak corresponding to
the Great Wall.Comment: 16 page
Photoinduced Fano-resonance of coherent phonons in zinc
Utilizing femtosecond optical pump-probe technique, we have studied transient
Fano-resonance in zinc. At high excitation levels the Fourier spectrum of the
coherent E phonon exhibits strongly asymmetric line shape, which is well
modeled by the Fano function. The Fano parameter (1/Q) was found to be strongly
excitation fluence dependent while depending weakly on the initial lattice
temperature. We attribute the origin of the Fano-resonance to the coupling of
coherent phonon to the electronic continuum, with their transition
probabilities strongly renormalized in the vicinity of the photoinduced
structural transition.Comment: 5 pages, 3 figures, to be published in Physical Review
The Impact of Link Suggestions on User Navigation and User Perception
The study reported in this paper explores the effects of providing web users with link suggestions that are relevant to their tasks. Results indicate that link suggestions were positively received. Furthermore, users perceived sites with link suggestions as more usable and themselves as less disoriented. The average task execution time was significantly lower than in the control condition and users appeared to navigate in a more structured manner. Unexpectedly, men took more advantage from link suggestions than women
Out-of-plane dielectric constant and insulator-superconductor transition in Bi_2Sr_2Dy_{1-x}Er_xCu_2O_8 single crystals
The out-of-plane dielectric constant of the parent insulator of the
high-temperature superconductor Bi_2Sr_2(Dy,Er)Cu_2O_8 was measured and
analysed from 80 to 300 K in the frequency range of 10^6-10^9 Hz. All the
samples were found to show a fairly large value of 10-60, implying some kind of
charge inhomogeneity in the CuO_2 plane. Considering that the superconducting
sample Bi_2Sr_2(Ca,Pr)Cu_2O_8 also shows a similar dielectric constant, the
charge inhomogeneity plays an important role in the insulator-superconductor
transition.Comment: RevTex4 format, 5 pages, 3 figures, submitted to J. Phys. Condens.
Ma
Vibrationally resolved partial cross sections and asymmetry parameters for carbon K-shell photoionization of the CO_2 molecule
We have measured the vibrationally resolved partial cross sections \sigma_{v_1^{\prime}} and asymmetry parameters \beta_{v_1^{\prime}} for C K-shell photoionization of the CO2 molecule in the Σu shape resonance region above the C K-shell ionization threshold. The positions of both the maxima of \sigma_{v_1^{\prime}} and the minima of \beta_{v_1^{\prime}} move towards the C K-shell threshold with increasing symmetric stretching vibrational excitation v'1 in the C 1s single-hole state. Calculations employing the relaxed-core Hartree–Fock approach reproduce the observed vibrational effects
Crystallization process and some properties of novel transparent machinable calcium-mica glass-ceramics
ArticleCERAMICS INTERNATIONAL. 34(1): 75-79 (2008)journal articl
Dissociative photoionization of the NO molecule studied by photoelectron-photon coincidence technique
Low-energy photoelectron–vacuum ultraviolet (VUV) photon coincidences have been measured using synchrotron radiation excitation in the inner-valence region of the nitric oxide molecule. The capabilities of the coincidence set-up were demonstrated by detecting the 2s−1 → 2p−1 radiative transitions in coincidence with the 2s photoelectron emission in Ne. In NO, the observed coincidence events are attributed to dissociative photoionization with excitation, whereby photoelectron emission is followed by fragmentation of excited NO+ ions into O+ + N* or N+ + O* and VUV emission from an excited neutral fragment. The highest coincidence rate occurs with the opening of ionization channels which are due to correlation satellites of the 3σ photoionization. The decay time of VUV photon emission was also measured, implying that specific excited states of N atoms contribute significantly to observed VUV emission
Lipocortin I (Annexin I) Is Preferentially Localized on the Plasma Membrane in Keratinocytes of Psoriatic Lesional Epidermis as Shown by Immunofluorescence Microscopy
Lopocortin I (LPC-I, also called annexin I) is a 35-kD protein that binds phospholidpids and actin ina a Ca++-dependetn manner. It is also a major substrate for EGF recepto/kinase and rotein kinase C,. and a putative inhibito of phospholipase A2, which produces chemical mediators to cause inflammation. Psoriasos (PS) is an inflammatory skin disease characterized by a rapid turnover of keratinocytes and a defect in keratinization with increased activities of phospholipase C and A2, and EGF receptor. To understand the mechanism of the PS lesion formation and the function of LPC-I, its didtribution was studied in the epiedermis of PS, subacure eczema and normal skin, and in tumor, cells of seborheic keratosis and Bowen's disease. This study involved immunofluorescence and immunoblotting using affinity-purified polyclonal and monclonal antibodies specific to LPC-I and to its Ca++- bound form. In normal, nonlesional PS and subacute eczema epidermis, LPC-I was detected , mainly in the cytoplasm of the suprabasal cells, although it was on the inner aspects of the plasma membrane in some parts of the granular layer. In lesional epidermis of PS it was localized mainly on the inner aspects of the plasma membrane, but not in the cytoplasm of the whole suprabasal cells as the Ca++-bond form, indicating a preferential localization of the plasma membrane. This membrane-binding of LPC-I was also observed in seborrheic keratosis, but not in Bowen's disease. These results suggest that the binding of LPC-I to the plasma membrane occurs actually in living cells, plays a role not necessarily disease specific, in the PS lesion formation, and has some relevance to normal or abnormal differentiation of keratinocytes
In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades
BACKGROUND: Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3. The mechanism of blister formation in pemphigus has not been defined; however, in vitro data suggest a role for activation of intracellular signalling cascades. OBJECTIVES: To investigate the contribution of these signalling pathways to the mechanism of PV IgG-induced acantholysis in vivo. METHODS: We used the passive transfer mouse model. Mice were injected with IgG fractions of sera from a patient with PV, with or without pretreatment with inhibitors of proteins that mediate intracellular signalling cascades. RESULTS: Inhibitors of tyrosine kinases, phospholipase C, calmodulin and the serine/threonine kinase protein kinase C prevented PV IgG-induced acantholysis in vivo. CONCLUSIONS: These observations strongly support the role of intracellular signalling cascades in the molecular mechanism of PV IgG-induced acantholysis
- …