346 research outputs found
Counting topological manifolds
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32762/1/0000133.pd
Suicide Attacks or "Martyrdom Operations" in Contemporary Jihad Literature
Martyrdom operations are a factor in contemporary
radical Islam. These operations have their roots in classical jihad
literature, but fundamentally are a by-product of widespread frustration and perceived humiliations on the part of Muslims. The attacks of
11 September 2001 are rooted within this tradition
Syzygies in equivariant cohomology for non-abelian Lie groups
We extend the work of Allday-Franz-Puppe on syzygies in equivariant
cohomology from tori to arbitrary compact connected Lie groups G. In
particular, we show that for a compact orientable G-manifold X the analogue of
the Chang-Skjelbred sequence is exact if and only if the equivariant cohomology
of X is reflexive, if and only if the equivariant Poincare pairing for X is
perfect. Along the way we establish that the equivariant cohomology modules
arising from the orbit filtration of X are Cohen-Macaulay. We allow singular
spaces and introduce a Cartan model for their equivariant cohomology. We also
develop a criterion for the finiteness of the number of infinitesimal orbit
types of a G-manifold.Comment: 28 pages; minor change
Umberto Eco, Narratives of Conspiracy and the Anti-Semite Among Us
http://www.quest-cdecjournal.it/discussion.php?id=3
Characteristics of transposable element exonization within human and mouse
Insertion of transposed elements within mammalian genes is thought to be an
important contributor to mammalian evolution and speciation. Insertion of
transposed elements into introns can lead to their activation as alternatively
spliced cassette exons, an event called exonization. Elucidation of the
evolutionary constraints that have shaped fixation of transposed elements
within human and mouse protein coding genes and subsequent exonization is
important for understanding of how the exonization process has affected
transcriptome and proteome complexities. Here we show that exonization of
transposed elements is biased towards the beginning of the coding sequence in
both human and mouse genes. Analysis of single nucleotide polymorphisms (SNPs)
revealed that exonization of transposed elements can be population-specific,
implying that exonizations may enhance divergence and lead to speciation. SNP
density analysis revealed differences between Alu and other transposed
elements. Finally, we identified cases of primate-specific Alu elements that
depend on RNA editing for their exonization. These results shed light on TE
fixation and the exonization process within human and mouse genes.Comment: 11 pages, 4 figure
Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD
OBJECTIVE: To develop a resource of systematically collected, longitudinal clinical data and biospecimens for assisting in the investigation into neuromyelitis optica spectrum disorder (NMOSD) epidemiology, pathogenesis, and treatment. METHODS: To illustrate its research-enabling purpose, epidemiologic patterns and disease phenotypes were assessed among enrolled subjects, including age at disease onset, annualized relapse rate (ARR), and time between the first and second attacks. RESULTS: As of December 2017, the Collaborative International Research in Clinical and Longitudinal Experience Study (CIRCLES) had enrolled more than 1,000 participants, of whom 77.5% of the NMOSD cases and 71.7% of the controls continue in active follow-up. Consanguineous relatives of patients with NMOSD represented 43.6% of the control cohort. Of the 599 active cases with complete data, 84% were female, and 76% were anti-AQP4 seropositive. The majority were white/Caucasian (52.6%), whereas blacks/African Americans accounted for 23.5%, Hispanics/Latinos 12.4%, and Asians accounted for 9.0%. The median age at disease onset was 38.4 years, with a median ARR of 0.5. Seropositive cases were older at disease onset, more likely to be black/African American or Hispanic/Latino, and more likely to be female. CONCLUSION: Collectively, the CIRCLES experience to date demonstrates this study to be a useful and readily accessible resource to facilitate accelerating solutions for patients with NMOSD
Situating Arab women’s writing in a feminist ‘global gothic’ : madness, mothers and ghosts
This article sketches a new way of approaching some contemporary Levantine (Egyptian and Lebanese) feminist texts. Extending Glennis Byron’s notion of the ‘global gothic’, I examine Hanan Al-Shaykh’s The Story of Zahra (1986), Mansoura Ez Eldin’s Maryam’s Maze (2007) and Joumana Haddad’s The Seamstress’ Daughter (2019) as examples of an Arab feminist Gothic approach, which serves as a framework to theorise difficult and pressing questions that feminism poses regarding women’s rights. Arab feminist Gothic writers use the jahiliyyah period, or the ‘time of ignorance’, as a folkloric referential backdrop for texts which theorise the female condition under contemporary patriarchal society. The presence of ghosts, madness, doubles in the form of the folkloric qarina spirit-doubles and dreams can be read as part of a local Gothic feminist mode. This as-yet unacknowledged Arab feminist Gothic tradition, while emerging from debates over statehood and postcolonial subjectivities, delves into the intensity of personal traumas through the lens of women’s relationships to other women, especially mothers and daughters. Taking Arab feminist fiction as its focus, this article models how feminist scholarship can use genre, particularly the Gothic, to trace artistic feminist theorising in non-western contexts
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