138 research outputs found
The Acute Phase Protein Ceruloplasmin as a Non-Invasive Marker of Pseudopregnancy, Pregnancy, and Pregnancy Loss in the Giant Panda
- Author
- AK Anagnostopoulos
- Andrew J. Kouba
- Barbara S. Durrant
- BG Steinetz
- BS Durrant
- C Jenkins
- CG Holmberg
- CI Vannucchi
- CJ Munro
- CW Denko
- David C. Kersey
- DC Kersey
- DC Kersey
- Erin L. Willis
- F Goritz
- FW Sunderman Jr
- G Curzon
- H Lowenstein
- H Markowitz
- H Zhang
- HH Taussky
- HH Taussky
- HO Hartley
- IB Kingston
- IM Goldstein
- J Hodges
- JF Griffin
- John P. Lydon
- JWW Neter
- K Steinman
- L Graham
- L Komlos
- L Komlos
- L McGeehan
- M Chaudhuri
- M Dehnhard
- M Sutherland-Smith
- M Zigril
- MM Fattah
- NM Czekala
- PA Ulutas
- R Medda
- RD Edmondson
- S Boivin
- S Burrows
- S Ellis
- S Osaki
- S Savion
- S Tangri
- SA Robertson
- SJ Wisdom
- SL Monfort
- T Tsubota
- TB Hildebrandt
- TP Ryan
- V Toder
- Z Serdar
- Publication venue
- Public Library of Science
- Publication date
- 13/07/2011
- Field of study
After ovulation, non-pregnant female giant pandas experience pseudopregnancy. During pseudopregnancy, non-pregnant females exhibit physiological and behavioral changes similar to pregnancy. Monitoring hormonal patterns that are usually different in pregnant mammals are not effective at determining pregnancy status in many animals that undergo pseudopregnancy, including the giant panda. Therefore, a physiological test to distinguish between pregnancy and pseudopregnancy in pandas has eluded scientists for decades. We examined other potential markers of pregnancy and found that activity of the acute phase protein ceruloplasmin increases in urine of giant pandas in response to pregnancy. Results indicate that in term pregnancies, levels of active urinary ceruloplasmin were elevated the first week of pregnancy and remain elevated until 20–24 days prior to parturition, while no increase was observed during the luteal phase in known pseudopregnancies. Active ceruloplasmin also increased during ultrasound-confirmed lost pregnancies; however, the pattern was different compared to term pregnancies, particularly during the late luteal phase. In four out of the five additional reproductive cycles included in the current study where females were bred but no birth occurred, active ceruloplasmin in urine increased during the luteal phase. Similar to the known lost pregnancies, the temporal pattern of change in urinary ceruloplasmin during the luteal phase deviated from the term pregnancies suggesting that these cycles may have also been lost pregnancies. Among giant pandas in captivity, it has been presumed that there is a high rate of pregnancy loss and our results are the first to provide evidence supporting this notion
Extra-Intestinal Manifestations of Familial Adenomatous Polyposis
- Author
- A Devic
- A Hansmann
- A Kartheuser
- AC Lockhart
- AJ Sigurdson
- AK Gurbuz
- AL Knudsen
- André P. van Beek
- Annemieke Roos
- AR Latchford
- B Seket
- BA Hirschman
- BR Rood
- C Bulow
- C Gupta
- CJ Stewart
- D Schweinitz von
- D Thomas
- DS Cooper
- E Papini
- EG Meir Van
- EI Traboulsi
- EJ Gardner
- EJ Gardner
- Emma J. Groen
- EW Naylor
- F Beuschlein
- F Cetta
- F Cetta
- F Cetta
- F Cetta
- F Maire
- F Paraf
- FM Giardiello
- FM Giardiello
- FM Giardiello
- FM Giardiello
- Friso L. Muntinghe
- G Ozuner
- GL Alexander
- HF Vasen
- HF Vasen
- HJ Jarvinen
- HW Crail
- I Heiskanen
- J Bjork
- J Bjork
- J Le Borgne
- J Turcot
- Jakob de Vries
- Jan H. Kleibeuker
- JC Healy
- JE Kingston
- JF Gebert
- JM Church
- JM Schnater
- JMG Wilson
- JS Wu
- K Chelaifa
- K Kubo
- KB Kaplan
- KH Goss
- KP Nugent
- L Bertario
- L Bertario
- L Ramaglia
- LJ Hughes
- LK Su
- LN Pho
- M Peifer
- M Phillips
- M Seki
- MA Wijn
- Max J. H. Witjes
- MC Frates
- MC Gallagher
- MF Herrera
- MH Nieuwenhuis
- MI Canto
- ML Bisgaard
- MM Grumbach
- MT Ballo
- N Yamakita
- NJ Sturt
- NR Schneider
- NS Fearnhead
- P Galiatsatos
- P Marchesa
- PJ Pines Corrales
- R Chetty
- R Fodde
- R Fodde
- R Valanzano
- RA Komorowski
- RM Reynolds
- RO Plail
- Roelien H. Enting
- RP Sanders
- RR Lonser
- S Aretz
- S Bulow
- S Bulow
- S Wakatsuki
- SB Middleton
- SK Clark
- SK Clark
- SR Hamilton
- T Iwama
- T Iwama
- T Matsumoto
- T Sudo
- T Takeuchi
- TA Painter
- TG Smith
- Thera P. Links
- TP Links
- VE Kimonis
- WH Marshall
- WK Hirota
- Z Traill
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2008
- Field of study
Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited disorder, which results from a germ line mutation in the APC (adenomatous polyposis coli) gene. FAP is characterized by the formation of hundreds to thousands of colorectal adenomatous polyps. Although the development of colorectal cancer stands out as the most prevalent complication, FAP is a multisystem disorder of growth. This means, it is comparable to other diseases such as the MEN syndromes, Von Hippel-Lindau disease and neurofibromatosis. However, the incidence of many of its clinical features is much lower. Therefore, a specialized multidisciplinary approach to optimize health care—common for other disorders—is not usually taken for FAP patients. Thus, clinicians that care for and counsel members of high-risk families should have familiarity with all the extra-intestinal manifestations of this syndrome. FAP-related complications, for which medical attention is essential, are not rare and their estimated lifetime risk presumably exceeds 30%. Affected individuals can develop thyroid and pancreatic cancer, hepatoblastomas, CNS tumors (especially medulloblastomas), and various benign tumors such as adrenal adenomas, osteomas, desmoid tumors and dental abnormalities. Due to improved longevity, as a result of better prevention of colorectal cancer, the risk of these clinical problems will further increase
The Salivary Secretome of the Tsetse Fly Glossina pallidipes (Diptera: Glossinidae) Infected by Salivary Gland Hypertrophy Virus
- Author
- A Abd-Alla
- A Abd-Alla
- A Conesa
- A Geiger
- A Hall
- A Watanabe
- A Wolfstein
- ABM Whitnall
- ACS Saphire
- Adly M. M. Abd-Alla
- AI Ince
- AM Colberg-Poley
- AMM Abd-Alla
- AMM Abd-Alla
- AMM Abd-Alla
- Andrew G. Parker
- AR Msangi
- AS Dugan
- AV Pisarev
- B Phillips
- B Rabe
- BA Furnari
- C Hagemeier
- C Sim
- CA Guerrero
- CA Janeway
- CD Steelman
- CH Nagel
- D Doyle
- D Kumar
- D Milburn
- DA Muruve
- DS Ellis
- E Calvo
- E Matovu
- E Turpin
- E Ungewickell
- EH Sklan
- EJ Haas-Stapleton
- EM Campbell
- EM Zdobnov
- EV Koonin
- FU Hartl
- FU Hartl
- G Caljon
- G Caljon
- G Caljon
- G Gribaudo
- G Gribaudo
- GA Belov
- GA Smith
- GG Maul
- GG Maul
- GP Saville
- GWG Luxton
- H Granzow
- H Mabit
- Henry M. Kariithi
- HM Kariithi
- HM Kariithi
- I Rapoport
- Ikbal A. Ince
- IP Lewis
- J Alves-Silva
- J Chroboczek
- J Cox
- J Cox
- J Cox
- J Dahl
- J Ma
- J Niewiarowska
- J Perez-Vargas
- J Van Den Abbeele
- JC Carolan
- JC Young
- Jesus G. Valenzuela
- JM Slack
- JM Slack
- JM Slack
- JMC Ribeiro
- JP Hendrichs
- JR Meyer
- Just M. Vlak
- K Dohner
- K Peng
- L Cerenius
- L Pirkkala
- L Yao
- LE Greene
- LR Chromy
- M Basaillon
- M Cappello
- M Hakim
- M Marek
- M Moore
- M Smede
- M Suomalainen
- M Suomalainen
- M Westenberg
- M Zhang
- MC Simon
- MG Delboy
- MG Santoro
- MJ Walport
- Monique M. van Oers
- MP Barrett
- MR D'Orsogna
- MR Kanost
- MV Rodnina
- NC Hubner
- ON Morris
- P Faulkner
- P Young
- PP Naranatt
- PS Cohen
- R Caswell
- R Caswell
- R Medzhitov
- R Wintjens
- RC Sang
- RD Everett
- RD Everett
- RE Kingston
- RH Gooding
- RI Morimoto
- RK Cheung
- RV Rio
- S Blandin
- S Hiramatsu
- S Li
- S Li
- S Lopez
- S Zarate
- SA Kelkar
- SC Braunagel
- Serap Aksoy
- Sjef Boeren
- SR Shih
- T Caldas
- T Dobner
- T Ohkawa
- T Stearns
- TGT Jaenson
- TP Newsome
- U Feldmann
- UF Greber
- UF Greber
- UF Greber
- UF Greber
- UF Greber
- UK Laemmli
- V Franssens
- V Jovasevic
- V Lallemand-Breitenbach
- V Moncollin
- V Rukmini
- W Lin
- WGZO Jura
- WGZO Jura
- WI Weis
- WO Sparks
- WO Sparks
- YA Chizmadzhev
- YN Xia
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Tsetse fly (Diptera; Glossinidae) transmits two devastating diseases to farmers (human African Trypanosomiasis; HAT) and their livestock (Animal African Trypanosomiasis; AAT) in 37 sub-Saharan African countries. During the rainy seasons, vast areas of fertile, arable land remain uncultivated as farmers flee their homes due to the presence of tsetse. Available drugs against trypanosomiasis are ineffective and difficult to administer. Control of the tsetse vector by Sterile Insect Technique (SIT) has been effective. This method involves repeated release of sterilized males into wild tsetse populations, which compete with wild type males for females. Upon mating, there is no offspring, leading to reduction in tsetse populations and thus relief from trypanosomiasis. The SIT method requires large-scale tsetse rearing to produce sterile males. However, tsetse colony productivity is hampered by infections with the salivary gland hypertrophy virus, which is transmitted via saliva as flies take blood meals during membrane feeding and often leads to colony collapse. Here, we investigated the salivary gland secretome proteins of virus-infected tsetse to broaden our understanding of virus infection, transmission and pathology. By this approach, we obtain insight in tsetse-hytrosavirus interactions and identified potential candidate proteins as targets for developing biotechnological strategies to control viral infections in tsetse colonies
A Treatment-Oriented Typology of Self-Identified Hypersexuality Referrals
- Author
- A Goodman
- Amy Lykins
- B Rush
- Bobbi R. Walling
- Carolin Klein
- D Kingston
- E Coleman
- E Coleman
- EO Laumann
- F Berlin
- FM Saleh
- G Corona
- J Bancroft
- J Money
- J Orford
- James M. Cantor
- JM Cantor
- Jordan E. Rullo
- Lea Thaler
- M Klein
- MC Quadland
- MF Mendez
- MH Orzack
- MJ Giudice Del
- MP Kafka
- MP Kafka
- MP Levine
- MS Kaplan
- R Blanchard
- R Blanchard
- RF Salmon
- RJ Barth
- SB Levine
- TP Sbraga
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family
- Author
- A Allouch
- A Corsinotti
- A Gupta
- A Hata
- A Hoffmann
- A Lupo
- A Paiva
- A Pelisson
- A Weng
- AA Aravin
- AB Conley
- AC Groner
- AF Smit
- AT Conroy
- AT Hamilton
- AV Persikov
- B Bodega
- B Lamprecht
- C Feschotte
- C Jolly
- C Lavialle
- C Mouse Genome Sequencing
- CB Lowe
- CE Gilling
- CE Grant
- CJ Cohen
- CJ Krebs
- CJ Krebs
- CJ Krebs
- CL Baker
- CP Walsh
- D Brinzevich
- D Ivanov
- D Schmidt
- D Wolf
- D Wolf
- D Wolf
- DC Hancks
- DC Leung
- DC Schultz
- DC Schultz
- DJ Mackay
- DJ Segal
- DR Nelson
- DS Johnson
- E Barklis
- EB Chuong
- ED Parvanov
- EJ Bellefroid
- EJ Grow
- EJ Yu
- ES Lander
- F Baudat
- F Fuks
- F Loreni
- FH Gage
- FM Jacobs
- FR Santoni de Sio
- G Coop
- G Guffanti
- G Kassiotis
- G Meroni
- G St Laurent 3rd
- G Wolf
- G Wolf
- H Kono
- H Liu
- H Nakahashi
- H Nishitsuji
- H Nishitsuji
- H O’Geen
- H Peng
- HA Michaud
- HC Chien
- HE Volkman
- HM Rowe
- HM Rowe
- HM Rowe
- HM Rowe
- HR Chung
- HS Najafabadi
- HS Rhee
- I Barde
- I Barde
- I Katoh
- I Lupan
- IA Maksakova
- IA Tchasovnikarova
- IL Berg
- J Hauschild-Quintern
- J Wang
- J Yun
- JA Law
- JA Plamondon
- JA Yoder
- JB Stavenhagen
- JF Margolin
- JG Mandell
- JH Thomas
- JH Thomas
- JH Thomas
- JJ Schwartz
- JL Buescher
- JR Friedman
- K Bojkowska
- K Nowick
- K Nowick
- K Okumura
- K Padjen
- K Saito
- K Tamura
- KA Carlson
- KA Carlson
- KJ Brayer
- KJ Brayer
- L Carbone
- L Carbone
- L Fasching
- L Reynolds
- L Robbez-Masson
- L Segurel
- L Shen
- LF Lin
- M Cowley
- M Horiba
- M Manghera
- M Ohnuki
- M Wiznerowicz
- M Worobey
- MA Carmell
- MA Hahn
- MC Marchetto
- MF Flajnik
- MJ Gonzalez-Hernandez
- MJ Vogel
- MM Karimi
- MS Lechner
- MT Reilly
- N Castro-Diaz
- NP Pavletich
- NP Pavletich
- O Mihola
- P Aiewsakun
- P Engler
- P Turelli
- PA Dumesic
- PJ Thompson
- PL Collins
- PL Oliver
- Q He
- R Cordaux
- R Jaenisch
- R Mahieux
- R Rizkallah
- R Strogantsev
- R Urrutia
- RC Edgar
- RJ Gifford
- RL Kingston
- RO Emerson
- RO Emerson
- S De Fazio
- S Frietze
- S Frietze
- S Furuta
- S Huntley
- S Iuchi
- S Lukic
- S Myers
- S Myers
- S Quenneville
- S Ratnam
- S Wissing
- S Yamanaka
- SE Ptak
- SH Lockwood
- SR Eberhardy
- SS Rao
- SY Yeo
- T Billings
- T Collins
- T Ishiuchi
- T Kleefstra
- T Matsui
- TP Loh
- TS Macfarlan
- TS Mikkelsen
- U Beyer
- UE Kalsoom
- V Sundaram
- VJ Lynch
- W Nietfeld
- W Winckler
- WD Gifford
- X Li
- X Tan
- Y Liu
- YK Lee
- Z Birtle
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Adam Bourdarios C
- Adamczyk L
- Adamek L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
- Ai X
- Aielli G
- Aikot A
- Ait Tamlihat M
- Aitbenchikh B
- Aizenberg I
- Akbiyik M
- Akimov AV
- Akiyama D
- Akolkar NN
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Albouy GL
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi F
- Algren M
- Alhroob M
- Ali B
- Ali HMJ
- Ali S
- Alibocus SW
- Aliev M
- Alimonti G
- Alkakhi W
- Allaire C
- Allbrooke BMM
- Allen JF
- Allendes Flores CA
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alvarez Estevez M
- Alvarez Fernandez A
- Alves Cardoso M
- Alviggi MG
- Aly M
- Amaral Coutinho Y
- Ambler A
- Amelung C
- Amerl M
- Ames CG
- Amidei D
- Amor Dos Santos SP
- Amos KR
- Ananiev V
- Anastopoulos C
- Andeen T
- Anders JK
- Andrean SY
- Andreazza A
- Angelidakis S
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Anulli F
- Aoki M
- Aoki T
- Aparisi Pozo JA
- Aparo MA
- Aperio Bella L
- Appelt C
- Apyan A
- Aranzabal N
- Arcangeletti C
- Arce ATH
- Arena E
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Arnaez O
- Arnold H
- Artoni G
- Asada H
- Asai K
- Asai S
- Asbah NA
- Assamagan K
- Astalos R
- Atashi S
- Atkin RJ
- Atkinson M
- Atmani H
- Atmasiddha PA
- Augsten K
- Auricchio S
- Auriol AD
- Austrup VA
- Avolio G
- Axiotis K
- Azuelos G
- Babal D
- Bachacou H
- Bachas K
- Bachiu A
- Backman F
- Badea A
- Bagnaia P
- Bahmani M
- Bailey AJ
- Bailey VR
- Baines JT
- Baines L
- Bakalis C
- Baker OK
- Bakos E
- Bakshi Gupta D
- Balakrishnan V
- Balasubramanian R
- Baldin EM
- Balek P
- Ballabene E
- Balli F
- Baltes LM
- Balunas WK
- Balz J
- Banas E
- Bandieramonte M
- Bandyopadhyay A
- Bansal S
- Barak L
- Barakat M
- Barberio EL
- Barberis D
- Barbero M
- Barel MZ
- Barends KN
- Barillari T
- Barisits M-S
- Barklow T
- Baron Moreno DA
- Baron P
- Baroncelli A
- Barone G
- Barr AJ
- Barr JD
- Barranco Navarro L
- Barreiro Guimarães da Costa J
- Barreiro F
- Barron U
- Barros Teixeira MG
- Barsov S
- Bartels F
- Bartoldus R
- Barton AE
- Bartos P
- Basan A
- Baselga M
- Bassalat A
- Basso MJ
- Basson CR
- Bates RL
- Batlamous S
- Batley JR
- Batool B
- Battaglia M
- Battulga D
- Bauce M
- Bauer M
- Bauer P
- Bazzano Hurrell LT
- Beacham JB
- Beau T
- Beauchemin PH
- Becherer F
- Bechtle P
- Beck HP
- Becker K
- Becot C
- Beddall AJ
- Bednyakov VA
- Bee CP
- Beemster LJ
- Beermann TA
- Begalli M
- Begel M
- Behera A
- Behr JK
- Beirer JF
- Beisiegel F
- Belfkir M
- Bella G
- Bellagamba L
- Bellerive A
- Bellos P
- Beloborodov K
- Belyaev NL
- Benchekroun D
- Bendebba F
- Benhammou Y
- Benoit M
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Bergeaas Kuutmann E
- Berger N
- Bergmann B
- Beringer J
- Bernardi G
- Bernius C
- Bernlochner FU
- Bernon F
- Berry T
- Berta P
- Berthold A
- Bertram IA
- Bethke S
- Betti A
- Bevan AJ
- Bhamjee M
- Bhatta S
- Bhattacharya DS
- Bhattarai P
- Bhopatkar VS
- Bi R
- Bianchi RM
- Bianco G
- Biebel O
- Bielski R
- Biglietti M
- Billoud TRV
- Bindi M
- Bingul A
- Bini C
- Biondini A
- Birch-sykes CJ
- Bird GA
- Birman M
- Biros M
- Biryukov S
- Bisanz T
- Bisceglie E
- Biswal JP
- Biswas D
- Bitadze A
- Bjørke K
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Blumenthal J
- Bobbink GJ
- Bobrovnikov VS
- Boehler M
- Boehm B
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Bomben M
- Bona M
- Boonekamp M
- Booth CD
- Borbély AG
- Bordulev IS
- Borecka-Bielska HM
- Borgna LS
- Borissov G
- Bortoletto D
- Boscherini D
- Bosman M
- Bossio Sola JD
- Bouaouda K
- Bouchhar N
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bouquet R
- Boveia A
- Boyd J
- Boye D
- Boyko IR
- Bracinik J
- Brahimi N
- Brandt G
- Brandt O
- Braren F
- Brau B
- Brau JE
- Brener R
- Brenner L
- Brenner R
- Bressler S
- Britton D
- Britzger D
- Brock I
- Brooijmans G
- Brooks WK
- Brost E
- Brown LM
- Bruce LE
- Bruckler TL
- Bruckman de Renstrom PA
- Bruni A
- Bruni G
- Bruschi M
- Bruscino N
- Brüers B
- Buanes T
- Buat Q
- Buchin D
- Buckley AG
- Bulekov O
- Bullard BA
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
- Burlayenko O
- Burr JTP
- Burton CD
- Burzynski JC
- Busch EL
- Bussey PJ
- Butler JM
- Buttar CM
- Butterworth JM
- Buttinger W
- Buxo Vazquez CJ
- Buzykaev AR
- Büscher V
- Cabrera Urbán S
- Cadamuro L
- Caforio D
- Cai H
- Cai Y
- Cairo VMM
- Cakir O
- Calace N
- Calafiura P
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Calvet D
- Calvet S
- Calvet TP
- Calvetti M
- Camacho Toro R
- Camarda S
- Camarero Munoz D
- Camarri P
- Camerlingo MT
- Cameron D
- Camincher C
- Campanelli M
- Camplani A
- Canale V
- Canesse A
- Cantero J
- Cao Y
- Capocasa F
- Capua M
- Carbone A
- Cardarelli R
- Cardenas JCJ
- Cardillo F
- Carli T
- Carlino G
- Carlotto JI
- Carlson BT
- Carlson EM
- Carminati L
- Carnelli A
- Carnesale M
- Caron S
- Carquin E
- Carratta G
- Carrio Argos F
- Carrá S
- Carter JWS
- Carter TM
- Casado MP
- Caspar M
- Castiglia EG
- Castillo Garcia L
- Castillo Gimenez V
- Castillo FL
- Castro NF
- Catinaccio A
- Catmore JR
- Cavaliere V
- Cavalli N
- Cavasinni V
- Cekmecelioglu YC
- Celebi E
- Celli F
- Centonze MS
- Cepaitis V
- Cerny K
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cervato B
- Cervelli A
- Cesarini G
- Cetin SA
- Chadi Z
- Chakraborty D
- Chan J
- Chan WY
- Chapman JD
- Chapon E
- Chargeishvili B
- Charlton DG
- Charman TP
- Chatterjee M
- Chauhan C
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chen A
- Chen B
- Chen B
- Chen H
- Chen H
- Chen J
- Chen J
- Chen M
- Chen S
- Chen SJ
- Chen X
- Chen X
- Chen Y
- Cheng CL
- Cheng HC
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- Zhang R
- Zhang S
- Zhang T
- Zhang X
- Zhang X
- Zhang Y
- Zhang Y
- Zhang Z
- Zhang Z
- Zhao H
- Zhao P
- Zhao T
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng J
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
- Zhou B
- Zhou H
- Zhou N
- Zhou Y
- Zhu CG
- Zhu J
- Zhu Y
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
- Adolfo Rubinstein
- Adoubi Kassi Anicet
- Adroaldo Cesar Araujo Gaya
- Afshin Ostovar
- Agnes L Kadvan
- Agneta Sjöberg
- Agneta Yngve
- Agnès Le Port
- Agustinus Soemantri
- Agustín Perez-Londoño
- Ahmad A Zainuddin
- Ahmad Faudzi Yusoff
- Ahmad Reza Dorosty
- Ahmed A Madar
- Aida Pilav
- Aïcha Soumaré
- Akaninyene Otu
- Akihiro Yoshihara
- Akkumis Salhanova
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Alanna G da Silva
- Albertino Damasceno
- Alberto Barceló
- Alberto Palloni
- Albina A Fakhretdinova
- Alejandro Diaz
- Aleksander Giwercman
- Aleksandra Gomula
- Aleksandra Piwonska
- Alessandro Gialluisi
- Aletta E Schutte
- Alexander D Deev
- Alexandra M Cucu
- Alexandre C Pereira
- Alfonso Siani
- Alfonso Sousa-Poza
- Ali Ahmadi
- Ali Akbar Shayesteh
- Ali Esmaeili
- Ali Ghanbari
- Ali Reza Safarpour
- Alice Bonilla-Vargas
- Alicia Matijasevich
- Alina G Platonova
- Alina Kerimkulova
- Aline Meirhaeghe
- Aline P Batista
- Alireza Ansari-Moghaddam
- Alireza Khosravi
- Alireza Moslem
- Alireza Sadjadi
- Alisha N Wade
- Alison J Hayes
- Alison J Price
- Allan G Hill
- Allan Linneberg
- Almaz Sharman
- Altan Onat
- Aluisio Jd Barros
- Alun Evans
- Amalia De Curtis
- Amanda G Thrift
- Amanda J Cross
- Amaneh Shayanrad
- Ambady Ramachandran
- Amelia C Crampin
- Amina Barkat
- Amir Houshang Mehrparvar
- Amirabbas Momenan
- Ana Azevedo
- Ana B Crujeiras
- Ana Barradas-Pires
- Ana Carolina Mgn de Sá
- Ana D González-Alvarez
- Ana Henriques
- Ana I Rito
- Ana Jelaković
- Ana Maria B Menezes
- Ana P Ortiz
- Ana Paula C Cândido
- Anabela Mota-Pinto
- Anar Dushpanova
- Anastasia Markaki
- Anders Grøntved
- Andre L Guimaraes
- Andre P Kengne
- Andrea Gazzinelli
- Andrea Gualtieri
- Andrea Rodriguez-Martinez
- Andrea Rvr Horimoto
- Andrea Schneider
- Andrea Y Rodríguez
- Andrea Zentai
- Andreas Stang
- Andreia N Pizarro
- Andrew Kingston
- Andrew Reynolds
- Andrew Wong
- Andrzej Galbarczyk
- Andrzej Pająk
- Andrzej Więcek
- Anelise Reis Gaya
- Aneta Grajda
- Aneta Weres
- Anette Varbo
- Angel R Gonzalez
- Angela Chetrit
- Angela Döring
- Angela Spinelli
- Angelika Schaffrath Rosario
- Angelique Chan
- Angélica M Ochoa-Avilés
- Anie Marcil
- Anil Poudyal
- Anja L Madsen
- Anja Schienkiewitz
- Anna Bartosiewicz
- Anna Bugge
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- Anna Jansson
- Anna V Alieva
- Annamari Lundqvist
- Anne A Bjerregaard
- Anne Chinnock
- Anne Juolevi
- Anne Taylor
- Anne Tjonneland
- Anneke Blokstra
- Annette J Dobson
- Annette Peters
- Annika Rosengren
- Anthony Kafatos
- Antonia Trichopoulou
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- Antonio Cabrera de León
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- Antonio Pedro Graça
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- Antonisamy Belavendra
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- Konrad Jamrozik
- Konstantinos D Tambalis
- Konstantinos Gkiouras
- Kotsedi Daniel K Monyeki
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- Kremlin Wickramasinghe
- Krishna K Aryal
- Krista Fischer
- Kristine Allin
- Kristyna Zejglicova
- Kumiko Ohara
- Kurt Widhalm
- Kyungwon Oh
- Labros S Sidossis
- Lachmie Lall
- Lacramioara Brinduse
- Laetitia Huiart
- Laila El Ammari
- Lalka S Rangelova
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- Lars Lind
- Lars Wichstrøm
- Laura A Rodríguez-Villamizar
- Laura Censi
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- Stefan Söderberg
- Stefania Maggi
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- Valéria Regecová
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- Valter Barbosa Filho
- Vanessa Rouzier
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- Vasiliki Efthymiou
- Vassilis Zafiropulos
- Vayia Rarra
- Vedrana Sember
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- Veronica Mocanu
- Vesna Juresa
- Vesselka L Duleva
- Victor M Herrera
- Victor Matsudo
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- Vijaya Lingam
- Viktoria Anna Kovacs
- Viktoriya Furdela
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- Vilmundur Gudnason
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- Violeta Iotova
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- Viswanathan Mohan
- Viviana Guajardo
- Viviane C Cardoso
- Vladimir Kutsenko
- Wafaie W Fawzi
- Wan Mohamad Wan Bebakar
- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
- Wenbin Wei
- Wendy Van Lippevelde
- Wenhua Zhao
- Wichai Aekplakorn
- Willem A Hanekom
- William A Neal
- William R Tebar
- Wilma M Hopman
- Winsome R Parnell
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- Wojciech Drygas
- Wojciech Rusek
- Wolfgang Ahrens
- Wolfgang Kratzer
- Xenophon Theodoridis
- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Recommended from our members
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c
- Author
- Abbasi-Kangevari M
- Abu-Rmeileh NM
- Adambekov S
- Adams RJ
- Aekplakorn W
- Agdeppa IA
- Aghazadeh-Attari J
- Aguilar-Salinas CA
- Agyemang C
- Ahmad NA
- Ahmadi A
- Ahmadi N
- Ahmadi N
- Ahmed SH
- Ajlouni K
- Al Asfoor D
- Al Nsour M
- Al Qaoud NM
- Al-Hinai H
- Al-Lahou B
- Al-Lawati JA
- Alarouj M
- AlBuhairan F
- AlDhukair S
- Aldwairji MA
- Ali MM
- Alinezhad F
- Alkandari A
- Alomirah HF
- Aly E
- Amarapurkar DN
- Andersen LB
- Anderssen SA
- Andrade DS
- Anjana RM
- Ansari-Moghaddam A
- Aounallah-Skhiri H
- Aris T
- Arlappa N
- Aryal KK
- Assah FK
- Assembekov B
- Auvinen J
- Avdicova M
- Azad K
- Azimi-Nezhad M
- Azizi F
- Bacopoulou F
- Balakrishna N
- Bamoshmoosh M
- Banach M
- Bandosz P
- Banegas JR
- Barbagallo CM
- Barcelo A
- Baretic M
- Barrera L
- Basit A
- Batieha AM
- Batista AP
- Baur LA
- Bebakar WMW
- Belavendra A
- Ben Romdhane H
- Ben S
- Benchekor SM
- Benet M
- Bennett JE
- Berkinbayev S
- Bernabe-Ortiz A
- Berrios Carrasola X
- Bettiol H
- Beybey AF
- Bhargava SK
- Bikbov MM
- Bista B
- Bjerregaard P
- Bjertness E
- Bjertness MB
- Bjorkelund C
- Bloch KV
- Blokstra A
- Bo S
- Bobak M
- Boggia JG
- Bonaccio M
- Bonilla-Vargas A
- Borghs H
- Bovet P
- Brajkovich I
- Brenner H
- Brewster LM
- Brian GR
- Briceno Y
- Brito M
- Bugge A
- Buntinx F
- Cabrera de Leon A
- Caixeta RB
- Can G
- Candido APC
- Capanzana MV
- Capkova N
- Capuano E
- Capuano R
- Capuano V
- Cardoso VC
- Carlsson AC
- Carrillo-Larco RM
- Casanueva FF
- Censi L
- Cervantes-Loaiza M
- Chamnan P
- Chamukuttan S
- Chan Q
- Charchar FJ
- Chaturvedi N
- Chen H
- Cheraghian B
- Chirlaque M-D
- Chudek J
- Cifkova R
- Cirillo M
- Cisneros JZ
- Claessens F
- Cohen E
- Concin H
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- Costanzo S
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- Cruz JJ
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- Deepa M
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- Egbagbe EE
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- Erbel R
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- Evans RG
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- Fakhradiyev I
- Fall CH
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- van Valkengoed IGM
- van Zutphen EM
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- Viswanathan B
- Voutilainen A
- Vrkic TZ
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- Wang YX
- Wannamethee SG
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- Wedderkopp N
- Wei W
- Westbury LD
- Whincup PH
- Widhalm K
- Widyahening IS
- Wiecek A
- Wilks RJ
- Willeit J
- Willeit P
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- Wojtyniak B
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- Wong EB
- Wong NI
- Woodward M
- Wu FC
- Xu H
- Xu L
- Yaacob NA
- Yan L
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- Yoshihara A
- Younger-Coleman NO
- Yu Y
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- Yusoff AF
- Yusoff MFM
- Zainuddin AA
- Zamani F
- Zambon S
- Zampelas A
- Zaw KK
- Zdrojewski T
- Zeng Y
- Zhang Z-Y
- Zholdin B
- Zhou B
- Zimmet P
- Zitt E
- Zoghlami N
- Publication venue
- Nature Research
- Publication date
- 09/11/2023
- Field of study
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance
Recommended from our members
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Aarestrup J
- Abarca-Gomez L
- Abbasi-Kangevari M
- Abdeen ZA
- Abdrakhmanova S
- Abdurrahmonova Z
- Abril GL
- Abu-Rmeileh NM
- Acosta-Cazares B
- Adam I
- Adamczyk M
- Adams RJ
- Adu-Afarwuah S
- Aekplakorn W
- Afsana K
- Afzal S
- Agbor VN
- Agdeppa IA
- Aghazadeh-Attari J
- Agren A
- Aguenaou H
- Aguilar-Salinas CA
- Aguilar-Salinas CA
- Agyemang C
- Ahmad MH
- Ahmad NA
- Ahmadi A
- Ahmadi N
- Ahmadi N
- Ahmed I
- Ahmed SH
- Ahrens W
- Aitmurzaeva G
- Ajlouni K
- Al Asfoor D
- Al Hourani HM
- Al Nsour M
- Al Qaoud NM
- Al-Hazzaa HM
- Al-Hinai H
- Al-Lahou B
- Al-Lawati JA
- Al-Raddadi R
- Alarouj M
- AlBuhairan F
- AlDhukair S
- Aldwairji MA
- Alexius S
- Ali MM
- Alieva AV
- Alkandari A
- Alkerwi A
- Alkhatib BM
- Allin K
- Alomary SA
- Alomirah HF
- Alshangiti AM
- Alvarez-Pedrerol M
- Aly E
- Amarapurkar DN
- Amoah J
- Amougou N
- Amouyel P
- Andersen LB
- Anderssen SA
- Androutsos O
- Angquist L
- Anicet AK
- Anjana RM
- Ansari-Moghaddam A
- Anufrieva E
- Aounallah-Skhiri H
- Araujo J
- Ariansen I
- Aris T
- Arku RE
- Arlappa N
- Aryal KK
- Aspelund T
- Assah FK
- Assefa N
- Assembekov B
- Assuncao MCF
- Aung MS
- Auvinen J
- Avdicova M
- Avi S
- Azad K
- Azevedo A
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- Azizi F
- Babu BV
- Bacopoulou F
- Baharudin A
- Bahijri S
- Bajramovic I
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- Baker JL
- Baker JL
- Balakrishna N
- Balanova Y
- Bamoshmoosh M
- Banach M
- Banegas JR
- Baran J
- Baran R
- Barbagallo CM
- Barcelo A
- Baretic M
- Barkat A
- Barkat A
- Barnoya J
- Barradas-Pires A
- Barrera L
- Barreto M
- Barros AJD
- Barros MVG
- Bartosiewicz A
- Basit A
- Bastos JL
- Bata I
- Batieha AM
- Batista AP
- Batista RL
- Battakova Z
- Baur LA
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- Beutel ME
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- Bhutta ZA
- Bhutta ZA
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- Bikbov MM
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- Blokstra A
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- Soares FC
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- Sobngwi E
- Sodemann M
- Soderberg S
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- Soemantri A
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- Sorensen TIA
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- Soric M
- Soric M
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- Soumare A
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- Sparboe-Nilsen B
- Sparrenberger K
- Spencer PR
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- Staessen JA
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- Steene-Johannessen J
- Stehle P
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- Stergiou GS
- Stessman J
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- Stieber J
- Stockl D
- Stokwiszewski J
- Stoyanova E
- Stratton G
- Stronks K
- Strufaldi MW
- Sturua L
- Suarez-Medina R
- Suarez-Ortegon MF
- Suebsamran P
- Sugiyama M
- Suka M
- Sulo G
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- Sund M
- Sundstrom J
- Sung Y-T
- Sunyer J
- Suriyawongpaisal P
- Sweis NWG
- Swinburn BA
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- Takuro F
- Tambalis KD
- Tammesoo M-L
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- Tang X
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- van Valkengoed IGM
- Vanderschueren D
- Vanuzzo D
- Varbo A
- Varela-Moreiras G
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- Vasan SK
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- Velde ST
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- Vrkic TZ
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- Wambiya EOA
- Wanderley Junior RDS
- Wang C
- Wang H
- Wang L
- Wang L
- Wang M-D
- Wang N
- Wang Q
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- Wang Y-W
- Wang YX
- Wannamethee SG
- Wareham N
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- Webster-Kerr K
- Wedderkopp N
- Weghuber D
- Wei W
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- Westbury LD
- Whincup PH
- Wichstrom L
- Wickramasinghe K
- Widhalm K
- Widyahening IS
- Wiecek A
- Wild PS
- Wilks RJ
- Willeit J
- Willeit P
- Williams J
- Wilsgaard T
- Wirth JP
- Wojtyniak B
- Woldeyohannes M
- Wolf K
- Wong A
- Wong EB
- Wong JE
- Wong NI
- Wong TY
- Wong-McClure RA
- Woo J
- Woodward M
- Wu FC
- Wu H-Y
- Wu J
- Wu LJ
- Wu S
- Wyszynska J
- Xu H
- Xu L
- Yaacob NA
- Yamborisut U
- Yan L
- Yan W
- Yang L
- Yang X
- Yang Y
- Yardim N
- Yasuharu T
- Yiallouros PK
- Yngve A
- Yoosefi M
- Yoshihara A
- Yotov Y
- You QS
- You S-L
- Younger-Coleman NO
- Yu Y
- Yu Y-L
- Yusof SM
- Yusoff AF
- Yusoff MFM
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zakavi SR
- Zamani F
- Zambon S
- Zampelas A
- Zamrazilova H
- Zapata ME
- Zargar AH
- Zaw KK
- Zayed AA
- Zdrojewski T
- Zeglen M
- Zejglicova K
- Zeng Y
- Zentai A
- Zhang B
- Zhang L
- Zhang Z-Y
- Zhao D
- Zhao M-H
- Zhao W
- Zhecheva YV
- Zhen S
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu D
- Zimmet P
- Zins M
- Zitt E
- Zocalo Y
- Zoghlami N
- Zuziak M
- Publication venue
- Elsevier
- Publication date
- 14/03/2024
- Field of study
Background
Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods
We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median).
Findings
From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness.
Interpretation
The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity.
Funding
UK Medical Research Council, UK Research and Innovation (Research England), UK Research and Innovation (Innovate UK), and European Union
Combined measurement of the Higgs boson mass from the H → γγ and H → ZZ∗ → 4ℓ decay channels with the ATLAS detector using √s = 7, 8, and 13 TeV pp collision data
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- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
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- Acharya BS
- Adam Bourdarios C
- Adamczyk L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
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- Akbiyik M
- Akimov AV
- Akiyama D
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- Zenger DT
- Zenin O
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- Zerwas D
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- Zhang Z
- Zhao H
- Zhao P
- Zhao T
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- Zhao Z
- Zhemchugov A
- Zheng J
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
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- Zhu CG
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- Zhu Y
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- Zhuang X
- Zhukov K
- Zhulanov V
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2023
- Field of study
A measurement of the mass of the Higgs boson combining the
H
→
Z
Z
∗
→
4
ℓ
and
H
→
γ
γ
decay channels is presented. The result is based on
140
fb
−
1
of proton-proton collision data collected by the ATLAS detector during LHC run 2 at a center-of-mass energy of 13 TeV combined with the run 1 ATLAS mass measurement, performed at center-of-mass energies of 7 and 8 TeV, yielding a Higgs boson mass of
125.11
±
0.09
(
stat
)
±
0.06
(
syst
)
=
125.11
±
0.11
GeV
. This corresponds to a 0.09% precision achieved on this fundamental parameter of the Standard Model of particle physics
- …