190 research outputs found

    Young people with diabetes and their peers

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    Type 1 Diabetes (T1D) is amongst the most common form of chronic illness affecting young people in the UK. Self- management is crucial, but managing their T1D is often difficult for young people

    Evaluation of the Effectiveness of Disseminating Workplace Health Promotion Resources to Businesses

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    Encouraging workplaces to undertake health promotion is important yet little is known of the types of information small and medium size workplaces would find useful. Two resources on workplace health promotion were mailed to 213 workplaces. The resources provided information on the benefits of workplace health promotion, suggestions for low-cost activities and components of a sustainable program. 62% of respondents rated the resources as either ‘very useful’ or ‘somewhat useful’. Workplaces in ‘contemplation’ and ‘preparation’ stages of change for engaging in WHP were most likely to have undertaken an activity to support the health and well-being of employees or be intending to, as a result of reading the resources .The findings of this study provide useful information on the reach and impact of dissemination of health promotion resources by mail to workplaces, and particularly small businesses

    Diagnosis as a new beginning not an end: A participatory photovoice study on navigating an autism diagnosis in adulthood

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    Autistic people diagnosed in adulthood often report that the experience can be life-changing, but there are issues with the diagnostic pathway. Few studies consider the views of people currently seeking diagnosis or contextualise the experience of diagnosis around developing an autistic identity. In this qualitative participatory study, we explored experiences of navigating an autism diagnosis in adulthood in the UK. We recruited six women (aged 21–46 years) who were seeking diagnosis, who worked with the academic researchers across four sessions to develop the study, share their experiences and analyse the themes. In one session, they completed a semi-structured interview alongside photovoice, a community-based action method, to explain and reflect on their experiences. We used reflexive thematic analysis to identify patterns, with four key themes identified: (1) ‘everything shattered’, (2) ‘being seen’, (3) ‘understanding not judgement, please’ and (4) ‘here’s a leaflet, off you go’. The themes reflected a desire for change and improved support for both diagnosis and developing autistic identity. Following photovoice methodology, together we identified actions to improve adult diagnosis, including involving autistic people in making improvements to the diagnostic criteria, for key professional and community groups to listen more to autistic people and for diagnostic support services to be flexible and appreciative of wider neurodivergence and intersectionality

    Current practice in academic workload allocation processes in Australia

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    Embarking on a large-scale research project to investigate aspects of academic workload management, it was first necessary to gain some understanding of current practice in that context within Australia. With that aim a pilot survey was conducted in 2013 that targeted Deans of Science on the one hand, and workload managers on the other. Survey questions covered three key areas related to workload management: models and rules; process and policy; and systems and software. Comparisons between different types of university, different allocation models for teaching, research and service components of academic workload, and different sizes of academic unit were explored. While the number of responses in absolute terms was relatively limited, and hence the outcomes were not always statistically testable or generalisable, broad trends were readily identifiable.  This paper reports on the method and outcomes of the survey, and describes how the information that was obtained has informed the development of an in-depth research project

    Hybrid assembly of an agricultural slurry virome reveals a diverse and stable community with the potential to alter the metabolism and virulence of veterinary pathogens

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    Background: Viruses are the most abundant biological entities on Earth, known to be crucial components of microbial ecosystems. However, there is little information on the viral community within agricultural waste. There are currently ~ 2.7 million dairy cattle in the UK producing 7–8% of their own bodyweight in manure daily, and 28 million tonnes annually. To avoid pollution of UK freshwaters, manure must be stored and spread in accordance with guidelines set by DEFRA. Manures are used as fertiliser, and widely spread over crop fields, yet little is known about their microbial composition. We analysed the virome of agricultural slurry over a 5-month period using short and long-read sequencing. Results: Hybrid sequencing uncovered more high-quality viral genomes than long or short-reads alone; yielding 7682 vOTUs, 174 of which were complete viral genomes. The slurry virome was highly diverse and dominated by lytic bacteriophage, the majority of which represent novel genera (~ 98%). Despite constant influx and efflux of slurry, the composition and diversity of the slurry virome was extremely stable over time, with 55% of vOTUs detected in all samples over a 5-month period. Functional annotation revealed a diverse and abundant range of auxiliary metabolic genes and novel features present in the community, including the agriculturally relevant virulence factor VapE, which was widely distributed across different phage genera that were predicted to infect several hosts. Furthermore, we identified an abundance of phage-encoded diversity-generating retroelements, which were previously thought to be rare on lytic viral genomes. Additionally, we identified a group of crAssphages, including lineages that were previously thought only to be found in the human gut. Conclusions: The cattle slurry virome is complex, diverse and dominated by novel genera, many of which are not recovered using long or short-reads alone. Phages were found to encode a wide range of AMGs that are not constrained to particular groups or predicted hosts, including virulence determinants and putative ARGs. The application of agricultural slurry to land may therefore be a driver of bacterial virulence and antimicrobial resistance in the environment. [MediaObject not available: see fulltext.
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