Establishing the boundaries: the hippocampal contribution to imagining scenes

When we visualize scenes, either from our own past or invented, we impose a viewpoint for our “mind's eye” and we experience the resulting image as spatially coherent from that viewpoint. The hippocampus has been implicated in this process, but its precise contribution is unknown. We tested a specific hypothesis based on the spatial firing properties of neurons in the hippocampal formation of rats, that this region supports the construction of spatially coherent mental images by representing the locations of the environmental boundaries surrounding our viewpoint. Using functional magnetic resonance imaging, we show that hippocampal activation increases parametrically with the number of enclosing boundaries in the imagined scene. In contrast, hippocampal activity is not modulated by a nonspatial manipulation of scene complexity nor to increasing difficulty of imagining the scenes in general. Our findings identify a specific computational role for the hippocampus in mental imagery and episodic recollection

Redshifts of the Gravitational Lenses MG1131+0456 and B1938+666

The redshifts of the gravitational lens galaxies in MG1131+0456 and B1938+666 are 0.844 and 0.881 respectively. Both are early-type galaxies lying at the redshifts predicted by assuming that they are early-type galaxies with old stellar populations lying on the fundamental plane. We also find evidence for a foreground group of galaxies at z=0.343 near MG1131+0456. The source redshifts are predicted to be >1.8 in both systems, but they are so red that infrared spectra will be required to determine their redshifts.Comment: 10 pages, AASTeX Latex, including 1 JPEG and 2 postscript figures, submitted to Astronomical Journal Minor typos fixe

The Wisdom of the Strict Locality Rule

Unlike the preceding article, this article favors the retention of the strict locality rule in medical malpractice cases in Maryland. The authors, after analyzing many of the arguments put forth to liberalize or extinguish Maryland\u27s version of the strict locality rule, discuss the case history that has solidified Maryland\u27s position and demonstrate the justification for the rule\u27s continued application in this jurisdiction

The Wisdom of the Strict Locality Rule

Unlike the preceding article, this article favors the retention of the strict locality rule in medical malpractice cases in Maryland. The authors, after analyzing many of the arguments put forth to liberalize or extinguish Maryland\u27s version of the strict locality rule, discuss the case history that has solidified Maryland\u27s position and demonstrate the justification for the rule\u27s continued application in this jurisdiction

The geology of Pine and Crater Buttes: Two basaltic constructs on the far eastern Snake River Plain

The emplacement history and petrochemical evolution of the volcanics associated with Pine Butte, Crater Butte, and other nearby vents are developed and described. Four major vents were identified in the study area and their associated eruptive products were mapped. All of the vents show a marked physical elongation or linear orientation coincident with the observed rift set. Planetary exploration has revealed the importance of volcanic processes in the genesis and modification of extraterrestrial surfaces. Interpretation of surface features has identified plains-type basaltic volcanism in various mare regions of the Moon and the volcanic provinces of Mars. Identification of these areas with features that appear analogous to those observed in the Pine Butte area suggests similar styles of eruption and mode of emplacement. Such terrestrial analogies serve as a method to interpret the evolution of volcanic planetary surfaces on the inner planets

CGUG: in silico proteome and genome parsing tool for the determination of "core" and unique genes in the analysis of genomes up to ca. 1.9 Mb

<p>Abstract</p> <p>Background</p> <p>Viruses and small-genome bacteria (~2 megabases and smaller) comprise a considerable population in the biosphere and are of interest to many researchers. These genomes are now sequenced at an unprecedented rate and require complementary computational tools to analyze. "CoreGenesUniqueGenes" (CGUG) is an <it>in silico </it>genome data mining tool that determines a "core" set of genes from two to five organisms with genomes in this size range. Core and unique genes may reflect similar niches and needs, and may be used in classifying organisms.</p> <p>Findings</p> <p>CGUG is available at <url>http://binf.gmu.edu/geneorder.html</url> as a web-based on-the-fly tool that performs iterative BLASTP analyses using a reference genome and up to four query genomes to provide a table of genes common to these genomes. The result is an <it>in silico </it>display of genomes and their proteomes, allowing for further analysis. CGUG can be used for "genome annotation by homology", as demonstrated with <it>Chlamydophila </it>and <it>Francisella </it>genomes.</p> <p>Conclusion</p> <p>CGUG is used to reanalyze the ICTV-based classifications of bacteriophages, to reconfirm long-standing relationships and to explore new classifications. These genomes have been problematic in the past, due largely to horizontal gene transfers. CGUG is validated as a tool for reannotating small genome bacteria using more up-to-date annotations by similarity or homology. These serve as an entry point for wet-bench experiments to confirm the functions of these "hypothetical" and "unknown" proteins.</p

Low energy ion scattering

Low energy ion scattering (LEIS) is the study of the composition and structure of a surface by the detection of low energy ions with energies ranging from 100 eV to 10 keV elastically scattered off the surface. The extreme sensitivity to the outermost atomic layer makes it as a unique tool for surface analysis. In this paper, concepts of shadowing, blocking, and also polar and azimuthal scans have been described. Surface order and surface atom spacings are revealed by using these concepts and measuring the intensity of backscattered projectiles as a function of the incident and azimuthal angles

Measurement of Untruncated Nuclear Spin Interactions via Zero- to Ultra-Low-Field Nuclear Magnetic Resonance

Zero- to ultra-low-field nuclear magnetic resonance (ZULF NMR) provides a new regime for the measurement of nuclear spin-spin interactions free from effects of large magnetic fields, such as truncation of terms that do not commute with the Zeeman Hamiltonian. One such interaction, the magnetic dipole-dipole coupling, is a valuable source of spatial information in NMR, though many terms are unobservable in high-field NMR, and the coupling averages to zero under isotropic molecular tumbling. Under partial alignment, this information is retained in the form of so-called residual dipolar couplings. We report zero- to ultra-low-field NMR measurements of residual dipolar couplings in acetonitrile-2-$^{13}$C aligned in stretched polyvinyl acetate gels. This represents the first investigation of dipolar couplings as a perturbation on the indirect spin-spin $J$-coupling in the absence of an applied magnetic field. As a consequence of working at zero magnetic field, we observe terms of the dipole-dipole coupling Hamiltonian that are invisible in conventional high-field NMR. This technique expands the capabilities of zero- to ultra-low-field NMR and has potential applications in precision measurement of subtle physical interactions, chemical analysis, and characterization of local mesoscale structure in materials.Comment: 6 pages, 3 figure

Major Powers and Militarized Conflict

This article attempts to answer the question of why major powers engage in more active foreign policy behaviors than minor powers. It does so by comparing two explanations for the increased conflict propensity of major powers. The first explanation focuses on major powers’ observable capabilities, while the second stresses their different behavior. We incorporate both into an ultimatum model of conflict in which a state’s cost of conflict consists of both observable and behavioral components. Using data from the period from 1870 to 2001, we empirically illustrate the observable and behavioral differences between major and minor powers. We then utilize a decomposition model to assess the relative significance of the two explanations. The results suggest that most of the difference in conflict propensity between major and minor powers can be attributed to observable differences