17,343 research outputs found
Quantum linear amplifier enhanced by photon subtraction and addition
A deterministic quantum amplifier inevitably adds noise to an amplified
signal due to the uncertainty principle in quantum physics. We here investigate
how a quantum-noise-limited amplifier can be improved by additionally employing
the photon subtraction, the photon addition, and a coherent superposition of
the two, thereby making a probabilistic, heralded, quantum amplifier. We show
that these operations can enhance the performance in amplifying a coherent
state in terms of intensity gain, fidelity, and phase uncertainty. In
particular, the photon subtraction turns out to be optimal for the fidelity and
the phase concentration among these elementary operations, while the photon
addition also provides a significant reduction in the phase uncertainty with
the largest gain effect.Comment: published version, 7 pages, 9 figure
Forty-Four Pass Fibre Optic Loop for Improving the Sensitivity of Surface Plasmon Resonance Sensors
A forty-four pass fibre optic surface plasmon resonance sensor that enhances
detection sensitivity according to the number of passes is demonstrated for the
first time. The technique employs a fibre optic recirculation loop that passes
the detection spot forty- four times, thus enhancing sensitivity by a factor of
forty-four. Presently, the total number of passes is limited by the onset of
lasing action of the recirculation loop. This technique offers a significant
sensitivity improvement for various types of plasmon resonance sensors that may
be used in chemical and biomolecule detections.Comment: Submitted for publication; patent disclosure submitte
Universality class of the restricted solid-on-solid model with hopping
We study the restricted solid-on-solid (RSOS) model with finite hopping
distance , using both analytical and numerical methods. Analytically, we
use the hard-core bosonic field theory developed by the authors [Phys. Rev. E
{\bf 62}, 7642 (2000)] and derive the Villain-Lai-Das Sarma (VLD) equation for
the case which corresponds to the conserved RSOS (CRSOS) model
and the Kardar-Parisi-Zhang (KPZ) equation for all finite values of .
Consequently, we find that the CRSOS model belongs to the VLD universality
class and the RSOS models with any finite hopping distance belong to the KPZ
universality class. There is no phase transition at a certain finite hopping
distance contrary to the previous result. We confirm the analytic results using
the Monte Carlo simulations for several values of the finite hopping distance.Comment: 13 pages, 3 figure
Synthesis and Characterization of Azole Isoflavone Inhibitors of Aromatase
The synthesis and biological evaluation of a series of 2-azole and 2-thioazole isoflavones as potential aromatase inhibitors are described. Differences in inhibitory activity of triazole and imidazole inhibitors are rationalized with density functional theory to expose a key difference in the electronic structure of these molecules. In addition, difference binding spectra of inhibitors to immunoaffinity-purified aromatase produces classical Type II spectra consistent with coordination of the nitrogen lone pair electrons to the aromatase P450 heme
Synthesis and Characterization of Azole Isoflavone Inhibitors of Aromatase
The synthesis and biological evaluation of a series of 2-azole and 2-thioazole isoflavones as potential aromatase inhibitors are described. Differences in inhibitory activity of triazole and imidazole inhibitors are rationalized with density functional theory to expose a key difference in the electronic structure of these molecules. In addition, difference binding spectra of inhibitors to immunoaffinity-purified aromatase produces classical Type II spectra consistent with coordination of the nitrogen lone pair electrons to the aromatase P450 heme
Treatment Preferences for CAM in Children with Chronic Pain
CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls) (mean age = 14.5 years ± 2.4; range = 8–18 years) presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examine the relationships between CAM treatment preferences and patient's sociodemographic and clinical characteristics, as well as their self-reported level of functioning. Over 60% of patients elected to try at least one CAM approach for pain. The most popular CAM therapies were biofeedback, yoga and hypnosis; the least popular were art therapy and energy healing, with craniosacral, acupuncture and massage being intermediate. Patients with a diagnosis of fibromyalgia (80%) were the most likely to try CAM versus those with other pain diagnoses. In multivariate analyses, pain duration emerged as a significant predictor of CAM preferences. For mind-based approaches (i.e. hypnosis, biofeedback and art therapy), pain duration and limitations in family activities were both significant predictors. When given a choice of CAM therapies, this sample of children with chronic pain, irrespective of pain diagnosis, preferred non-invasive approaches that enhanced relaxation and increased somatic control. Longer duration of pain and greater impairment in functioning, particularly during family activities increased the likelihood that such patients agreed to engage in CAM treatments, especially those that were categorized as mind-based modalities
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