Dynamics of evaporative cooling in magnetically trapped atomic hydrogen

We study the evaporative cooling of magnetically trapped atomic hydrogen on the basis of the kinetic theory of a Bose gas. The dynamics of trapped atoms is described by the coupled differential equations, considering both the evaporation and dipolar spin relaxation processes. The numerical time-evolution calculations quantitatively agree with the recent experiment of Bose-Einstein condensation with atomic hydrogen. It is demonstrated that the balance between evaporative cooling and heating due to dipolar relaxation limits the number of condensates to 9x10^8 and the corresponding condensate fraction to a small value of 4% as observed experimentally.Comment: 5 pages, REVTeX, 3 eps figures, Phys. Rev. A in pres

Correction: Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial

BACKGROUND: Acute exacerbations contribute to the morbidity and mortality associated with chronic obstructive pulmonary disease (COPD). This proof-of-concept study evaluates whether intermittent pulsed moxifloxacin treatment could reduce the frequency of these exacerbations. METHODS: Stable patients with COPD were randomized in a double-blind, placebo-controlled trial to receive moxifloxacin 400 mg PO once daily (N = 573) or placebo (N = 584) once a day for 5 days. Treatment was repeated every 8 weeks for a total of six courses. Patients were repeatedly assessed clinically and microbiologically during the 48-week treatment period, and for a further 24 weeks' follow-up. RESULTS: At 48 weeks the odds ratio (OR) for suffering an exacerbation favoured moxifloxacin: per-protocol (PP) population (N = 738, OR 0.75, 95% confidence interval (CI) 0.565-0.994, p = 0.046), intent-to-treat (ITT) population (N = 1149, OR 0.81, 95% CI 0.645-1.008, p = 0.059), and a post-hoc analysis of per-protocol (PP) patients with purulent/mucopurulent sputum production at baseline (N = 323, OR 0.55, 95% CI 0.36-0.84, p = 0.006).There were no significant differences between moxifloxacin and placebo in any pre-specified efficacy subgroup analyses or in hospitalization rates, mortality rates, lung function or changes in St George's Respiratory Questionnaire (SGRQ) total scores. There was, however, a significant difference in favour of moxifloxacin in the SGRQ symptom domain (ITT: -8.2 vs -3.8, p = 0.009; PP: -8.8 vs -4.4, p = 0.006). Moxifloxacin treatment was not associated with consistent changes in moxifloxacin susceptibility. There were more treatment-emergent, drug related adverse events with moxifloxacin vs placebo (p < 0.001) largely due to gastrointestinal events (4.7% vs 0.7%). CONCLUSIONS: Intermittent pulsed therapy with moxifloxacin reduced the odds of exacerbation by 20% in the ITT population, by 25% among the PP population and by 45% in PP patients with purulent/mucopurulent sputum at baseline. There were no unexpected adverse events and there was no evidence of resistance development. TRIAL REGISTRATION: ClinicalTrials.gov number, NCT00473460 (ClincalTrials.gov)

Track A Basic Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd

Comparative osteology of the fossorial frogs of the genus Synapturanus (Anura, Microhylidae) with the description of three new species from the Eastern Guiana Shield

International audienc

Étude PREO – polyarthrite rhumatoïde séropositive associée à une hyperéosinophilie persistante : caractéristiques de 50 cas rétrospectifs

International audienc

System-scale airborne electromagnetic surveys in the lower Mississippi River Valley support multidisciplinary applications

&lt;p&gt;The lower Mississippi River Valley spans over 200,000 square kilometres in parts of seven states, encompassing areas of critical groundwater supplies, natural hazards, infrastructure, and low-lying coastal regions. From 2018 - 2022, the U.S. Geological Survey acquired over 82,000 line-kilometres of airborne electromagnetic, radiometric, and magnetic data over this region to provide comprehensive and systematic information about subsurface geologic and hydrologic properties that support multiple scientific and societal interests. Most of the data were acquired on a regional grid of west-east flight lines separated by 3 - 6 kilometres; however, several high-resolution inset grids with line spacing as close as 200 m were acquired in targeted areas of interest. Approximately 8,000 line-kilometres were acquired along streams and rivers to characterise the potential for surface water-groundwater connection, and another 6,000 line-kilometres were acquired along the Mississippi and Arkansas River levees to characterise this critical infrastructure. Here, we present a summary of the data along with several examples of how they are being used to inform regional groundwater model development, inferences of groundwater salinity, identification of faults in the New Madrid seismic zone, and levee infrastructure.&lt;/p&gt;Open-Access Online Publication: October 30, 202