Ei-proteiinityppi yksimahaisten kotieläinten lähinnä siipikarjan ravitsemuksessa

vKirjasto Aj-kTiivistelm

Smältbarhet av vegetabiliska proteinfodermedel hos mink = Digestibility of protein feedstuffs derived from plants in mink

vokKirjasto Aj-

Ruokinnan ja ympäristötekijöiden vaikutuksesta rehuhyötysuhteeseen yksimahaisilla kotieläimillä

vKirjasto Aj-

Feeding whole grain with pelleted diets to growing broiler chickens

In three trials with growing broilers (aged 12-8 days) the proportion of whole grain (WG) was increased step by step up to 30% (Trial 1) along with commercial starter (S) and grower (G) pellets or up to 40% (Trial 2) and 50% (Trial 3) with special balancer (BA) pellets (crude protein 250 g/kg). WG accounted for about 20%, 31% and 38% of the broilers’ total feed intakes, respectively. In Trial 1, the grain was exclusively wheat (W). In the other trials, also mixtures of wheat and barley (W:B 70:30, 50:50) were used. Crude protein analyses of feed remains revealed that birds did not to any considerable extent select between pellets and grain. Mixing wheat with S or G pellets reduced feed intake significantly (

The nutritive value of industrial by-products for poultry

The metabolizable energy (ME) and partly also the digestibility of several industrial by-products, mainly originating from grain, were determined in trials with adult cockerels. Five experiments were performed using a conventional total collection procedure, and test ingredients were substituted for 25-40 % of the basal diet. The nitrogen-corrected apparent (AMEn) and true (TMEn) metabolizable energy values of distillers’ dried grains (DDG) and distillers’ dried grains with solubles (DDGS) derived from barley, wheat and rye varied from 7.85 to 11.8 and from 7.98 to 12.0 MJ/ kg DM, respectively. The highest MEn values were observed in the dehulled barley-derived products. The digestibility of crude protein (CP) was 62-83 and that of carbohydrates 25-50 %, the latter being lowest for feeds originating from whole barley grain. The results indicated that distillers’ feeds derived from dehulled grain, especially barley, are satisfactory energy sources for poultry diets. Dried barley protein (BP 1, CP 38 %), oats protein (CP 44 %) and distillers’ solids (CP 58 %) from the integrated ethanol starch process, as well as dehulled barley and oats proved to be excellent energy feeds containing AMEn 14.9, 18.6, 15.0, 14.2 and 14.6 MJ/kg DM, respectively. The TMEn values for BPI and dehulled grains were 15.3, 14.4 and 14.8 MJ/kg DM. Supplementation with enzymes did not significantly improve the ME value of dehulled barley. The AMEn values for barley protein (BP2, CP 27 %), barley bran and barley molasses obtained from the starch process, and wheat feed meal from the milling industry, were 13.3, 8.52, 13.5 and 10.6 MJ/kg DM, respectively. The lowest ME values were obtained for samples of wheat bran, dried potato pulp and malt sprouts: AMEn 6.09, 6.23 and 6.01; TMEn 6.15, 6.07 and 6.01 MJ/kg DM, respectively

Research reports of Pekilo-symposium : Tampere 12-15.9.1978

vKirjasto Aj-

Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line

Extinction and reinstatement of morphine-induced conditioned place preference were studied in glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-receptor GluA1 subunit-deficient mice (global GluA1-KO mice). In line with previous findings, both acquisition and expression of conditioned place preference to morphine (20 mg/kg, subcutaneously) were fully functional in GluA1 KO mice compared with wild-type littermate controls (GluA1-WT), thus enabling the study of extinction. With a 10-session extinction paradigm, the GluA1 KO mice showed complete extinction similar to that of the GluA1-WT mice. Morphine-induced reinstatement (10 mg/kg, subcutaneously) was detected in both mouse lines. GluA1 KO mice moved more during all the phases of the experiment, including the place conditioning trials, extinction sessions, and place preference tests. The results suggest that the GluA1 subunit may be dispensable or prone to compensation at the neural circuitries delineating extinction and reinstatement. The GluA1 KO mice show altered long-term between-session habituation, which extends longer than previously anticipated.Peer reviewe

Effects of a short laying rest on postrest egg production and egg quality

Two factorial trials, each including three commercial laying hybrids, were conducted to study the effects of a short laying rest on postrest performance of hens and on egg quality. A total of 1800 hens laying at 65% on an average (70 wks of age) were subjected to one of the following treatments: no rest (control, C) or feeding only whole-grain barley (WB) or fasting (F, Trial 1 only) until the rate oflay dropped to 0%, after which the birds were returned to the previous all-mash diet. The second laying period was six months. Egg production of the WB and F hens ceased within one week on an average and the birds were out of production for 10 days. Laying intensity during the second production period did not differ significantly between the treatments in each trial, but egg weight and daily egg mass production increased as a result of the rest treatments. The laying rest procedures reduced feed intake, improved feed efficiency and increased live weight significantly. Egg shell and albumen quality traits were significantly better in the laying rest groups than in the controls. Significant differences in performance and egg quality between the hybrids were mainly ascertained in Trial 2. The results suggest that a short laying rest is a feasible means of improving egg quality towards the end of the laying period. It can be accomplished successfully by feeding whole-grain barley

Accumulation of dietary fish fatty acids in the body fat reserves of some carnivorous fur-bearing animals

Body fat composition of the mink (Mustela vison), polecat (Mustela putorius), and the raccoon dog (Nyctereutes procyonoides) was studied. The animals were fed a wet diet, supplemented with 5 % lard (LA) or fish oil (FO) for 5-6 months. At pelting, five animals per dietary group were sampled. Dietary levels of cetoleic (C22:1ω11), eicosapentaenoic (EPA, C20:5ω3), and docosahexaenoic (DHA, C22:6ω3) acids were 0.4, 0.3, and 0.5% in the fat of the LA diet, and 7.6, 4.2 and 4.3% in the FO diet, respectively. In the FO diet, EPA and DHA accumulated especially in the liver and heart, while cetoleic acid showed the highest affinity to the heart muscle and subcutaneous fat. The highest levels of EPA were found in raccoon dogs and polecats fed the FO diet. The mean EPA levels ranged from 6.7-9.3% in the liver fat and 7.2-8.0% in the heart muscle fat. In the mink, the corresponding values were 2.7% and 3.9%, respectively. DHA levels were the highest in the liver fat of the polecats, being 18.5% in the FO diet. In addition, the liver in raccoon dogs fed the FO diet (13.8%) differed significantly from themink (9.4%). The differences in the accumulation of these long-chained marine fatty acids were apparently caused by species differences in the efficiency of their peroxisomal β-oxidation

Clinical Conditions and Their Impact on Utility of Genetic Scores for Prediction of Acute Coronary Syndrome

Background: Acute coronary syndrome (ACS) is a clinically significant presentation of coronary heart disease. Genetic information has been proposed to improve prediction beyond well-established clinical risk factors. While polygenic scores (PS) can capture an individual's genetic risk for ACS, its prediction performance may vary in the context of diverse correlated clinical conditions. Here, we aimed to test whether clinical conditions impact the association between PS and ACS. Methods: We explored the association between 405 clinical conditions diagnosed before baseline and 9080 incident cases of ACS in 387 832 individuals from the UK Biobank. Results were replicated in 6430 incident cases of ACS in 177 876 individuals from FinnGen. Results: We identified 80 conventional (eg, stable angina pectoris and type 2 diabetes) and unconventional (eg, diaphragmatic hernia and inguinal hernia) associations with ACS. The association between PS and ACS was consistent in individuals with and without most clinical conditions. However, a diagnosis of stable angina pectoris yielded a differential association between PS and ACS. PS was associated with a significantly reduced (interaction P=2.87x10(-8)) risk for ACS in individuals with stable angina pectoris (hazard ratio, 1.163 [95% CI, 1.082-1.251]) compared with individuals without stable angina pectoris (hazard ratio, 1.531 [95% CI, 1.497-1.565]). These findings were replicated in FinnGen (interaction P=1.38x10(-6)). Conclusions: In summary, while most clinical conditions did not impact utility of PS for prediction of ACS, we found that PS was substantially less predictive of ACS in individuals with prevalent stable coronary heart disease. PS may be more appropriate for prediction of ACS in asymptomatic individuals than symptomatic individuals with clinical suspicion for coronary heart disease.Peer reviewe