408 research outputs found
Evolution of nano-pores during annealing of technically pure molybdenum sheet produced from different sintered formats
Molybdenum is a refractory metal with no phase transformation in the solid state and a high melting point. It is therefore an excellent structural material for various high temperature applications. Especially in this field of operation, significant creep resistance is essential. To achieve this, a microstructure with grains in the range of millimeters is desired. However, as demonstrated in the present study, the onset temperature for secondary recrystallization, which would lead to a beneficial grain size, is among other things dependent on the initial dimensions of the sintered part. One possible reason for the different microstructural evolutions is the influence of residual pores in sub-micrometer size. Sheets were thus fabricated via three different production routes employing the same initial Mo powder to exclude chemical variation as an influencing factor. The samples were investigated by in-situ small-angle X-ray scattering at a synchrotron radiation source with two different heating rates. Additionally, selected annealed samples were studied ex-situ with high energy X-rays. The apparent volume fraction of pores is compared to a volatilization model for the vaporization of typical accompanying elements and the induced thermal expansion
Spectroscopy of Ne for the thermonuclear O()Ne and F()O reaction rates
Uncertainties in the thermonuclear rates of the
O()Ne and F()O reactions
affect model predictions of light curves from type I X-ray bursts and the
amount of the observable radioisotope F produced in classical novae,
respectively. To address these uncertainties, we have studied the nuclear
structure of Ne over MeV and MeV using
the F(He,t)Ne reaction. We find the values of the
4.14 and 4.20 MeV levels to be consistent with and
respectively, in contrast to previous assumptions. We confirm the recently
observed triplet of states around 6.4 MeV, and find evidence that the state at
6.29 MeV, just below the proton threshold, is either broad or a doublet. Our
data also suggest that predicted but yet unobserved levels may exist near the
6.86 MeV state. Higher resolution experiments are urgently needed to further
clarify the structure of Ne around the proton threshold before a
reliable F()O rate for nova models can be determined.Comment: 5 pages, 3 figures, Phys. Rev. C (in press
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Cadherin-11 regulates synovial fibroblast behavior in health and disease
Gamma ray production cross sections in proton induced reactions on natural Mg, Si and Fe targets over the proton energy range 30 up to 66 MeV
Gamma-ray excitation functions have been measured for 30, 42, 54 and 66 MeV
proton beams accelerated onto C + O (Mylar), Mg, Si, and Fe targets of
astrophysical interest at the separate-sector cyclotron of iThemba LABS in
Somerset West (Cape Town, South Africa). A large solid angle, high energy
resolution detection system of the Eurogam type was used to record Gamma-ray
energy spectra. Derived preliminary results of Gamma-ray line production cross
sections for the Mg, Si and Fe target nuclei are reported and discussed. The
current cross section data for known, intense Gamma-ray lines from these nuclei
consistently extend to higher proton energies previous experimental data
measured up to Ep ~ 25 MeV at the Orsay and Washington tandem accelerators.
Data for new Gamma-ray lines observed for the first time in this work are also
reported.Comment: 11 pages, 6 figures. IOP Institute of Physics Conference Nuclear
Physics in Astrophysics VII, 28th EPF Nuclear Physics Divisional Conference,
May 18-22 2015, York, U
interference in the Coulomb dissociation of B
We investigate the effects arising out of the interference in the
Coulomb dissociation of B at beam energies below and around 50 MeV/nucleon.
The theory has been formulated within a first order semiclassical scheme of
Coulomb excitation, in which both the ground state and the continuum state wave
functions of B enter as inputs. We find that the magnitude of the
interference could be large in some cases. However, there are some specific
observables which are free from the effects of the interference,
which is independent of the models used to describe the structure of B.
This will be useful for the analysis of the breakup data in relation to the
extraction of the astrophysical factor .Comment: Revised version to appear in Physical Review
Low energy measurement of the 7Be(p,gamma)8B cross section
We have measured the cross section of the 7Be(p,gamma)8B reaction for E_cm =
185.8 keV, 134.7 keV and 111.7 keV using a radioactive 7Be target (132 mCi).
Single and coincidence spectra of beta^+ and alpha particles from 8B and 8Be^*
decay, respectively, were measured using a large acceptance spectrometer. The
zero energy S factor inferred from these data is 18.5 +/- 2.4 eV b and a
weighted mean value of 18.8 +/- 1.7 eV b (theoretical uncertainty included) is
deduced when combining this value with our previous results at higher energies.Comment: Accepted for publication in Phys. Rev. Let
S17(0) Determined from the Coulomb Breakup of 83 MeV/nucleon 8B
A kinematically complete measurement was made of the Coulomb dissociation of
8B nuclei on a Pb target at 83 MeV/nucleon. The cross section was measured at
low relative energies in order to infer the astrophysical S factor for the
7Be(p,gamma)8B reaction. A first-order perturbation theory analysis of the
reaction dynamics including E1, E2, and M1 transitions was employed to extract
the E1 strength relevant to neutrino-producing reactions in the solar interior.
By fitting the measured cross section from Erel = 130 keV to 400 keV, we find
S17(0) = 17.8 (+1.4, -1.2) eV b
PU.1 controls fibroblast polarization and tissue fibrosis
Fibroblasts are polymorphic cells with pleiotropic roles in organ morphogenesis, tissue homeostasis and immune responses. In fibrotic diseases, fibroblasts synthesize abundant amounts of extracellular matrix, which induces scarring and organ failure. By contrast, a hallmark feature of fibroblasts in arthritis is degradation of the extracellular matrix because of the release of metalloproteinases and degrading enzymes, and subsequent tissue destruction. The mechanisms that drive these functionally opposing pro-fibrotic and pro-inflammatory phenotypes of fibroblasts remain unknown. Here we identify the transcription factor PU.1 as an essential regulator of the pro-fibrotic gene expression program. The interplay between transcriptional and post-transcriptional mechanisms that normally control the expression of PU.1 expression is perturbed in various fibrotic diseases, resulting in the upregulation of PU.1, induction of fibrosis-associated gene sets and a phenotypic switch in extracellular matrix-producing pro-fibrotic fibroblasts. By contrast, pharmacological and genetic inactivation of PU.1 disrupts the fibrotic network and enables reprogramming of fibrotic fibroblasts into resting fibroblasts, leading to regression of fibrosis in several organs
Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with Systemic Sclerosis and do not influence gene expression
1 página.-- Póster presentado al 5º European Workshop on Immune-Mediated Inflammatory Diseases celebrado en Sitges (Barcelona, Españ) del 1 al 3 de Diciembre de 2010.-- et al.Peer reviewe
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