Modern Integrated Associations: Comparative Analysis of Economic Growth Factors

In the article, the results of the research, which purpose is to ground and assess the factors of economic growth of regional integration communities and national economies of member countries that develop them, are presented. The foreign trade, mutual trade turnover, and domestic demand are allocated as such factors. The authors has applied the novelty in their methodology which in contrast to the traditional assessment method of growth factors of integration communities and their participants, is based on comparison of two components — external and domestic demand, based on dividing the external demand on two components: the first one is pure export (the difference between export and import is a component of cumulative demand) of goods in integration community, i.e. the pure export of mutual trade; the second one is a pure export of foreign trade of goods outside of the integration association. Scope of the research is seven most known regional integrated units arose at different times and being at different stages of development — the European Union, North American Free Trade Area, Association of Southeast Asian Nations, Southern American Common Market, Asia-Pacific Economic Cooperation, and also member countries of the Eurasian integration — the Customs Union and Common Free Market Zone developed into the Eurasian Economic Union in January 1, 2015. In conclusion, it is noted that the integration develops successfully only in the conditions of the rise in national economies of the participating countries. Crisis economies have to deal more with internal problems than to resolve integration issues.The article has been prepared within the project «Eurasian integration: asymmetries and efficiency» with financial support of the grant № 1275/GF4 of the Ministry of Education and Science of the Republic of Kazakhstan»

Longitudinal vibrations of underground pipelines of finite length in medium surrounded by soil with different properties along pipeline length

An analysis of the dynamic response of an underground main pipeline under a longitudinal wave propagating in soil along the pipe is given in the article. The problem of the longitudinal wave impact on a pipeline of finite length, interacting with soil according to the elastic-viscous law, is considered. The ends of the pipeline are fixed to massive nodes that interact with the medium according to linear laws. Along the length of the pipeline, the coefficients of the elastic and viscous pipeline-soil interaction change depending on the coordinate. In this article, the influence of the coefficients of elastic and viscous interaction of the "pipe-soil" system is studied when these coefficients are coordinate functions. The variability of the values of the coefficients along the length of the pipeline leads to a change in displacements from 0 to 15% and strain from 0 to 18%, compared with the case when these coefficients are constant. Depending on the length of the pipeline, the response of the pipeline to seismic action is different. This is especially evident at the boundary points. Considering the weight of nodes leads largely to a decrease in the strain of the pipeline relative to the soil strain at the boundary points

Absolute stability of time-varying delay Lurie indirect control systems with unbounded coefficients

This paper investigates the absolute stability problem of time-varying delay Lurie indirect control systems with variable coefficients. A positive-definite Lyapunov-Krasovskii functional is constructed. Some novel sufficient conditions for absolute stability of Lurie systems with single nonlinearity are obtained by estimating the negative upper bound on its total time derivative. Furthermore, the results are generalised to multiple nonlinearities. The derived criteria are especially suitable for time-varying delay Lurie indirect control systems with unbounded coefficients. The effectiveness of the proposed results is illustrated using simulation examples

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

he antibiotic target. One class of such proteins are the antibiotic resistance (ARE) ATP-binding cassette (ABC) proteins of the F-subtype (ARE-ABCFs), which are widely distributed throughout Gram-positive bacteria and bind the ribosome to alleviate translational inhibition from antibiotics that target the large ribosomal subunit. Here, we present single-particle cryo-EM structures of ARE-ABCF-ribosome complexes from three Gram-positive pathogens: Enterococcus faecalis LsaA, Staphylococcus haemolyticus VgaALC and Listeria monocytogenes VgaL. Supported by extensive mutagenesis analysis, these structures enable a general model for antibiotic resistance mediated by these ARE-ABCFs to be proposed. In this model, ABCF binding to the antibiotic-stalled ribosome mediates antibiotic release via mechanistically diverse long-range conformational relays that converge on a few conserved ribosomal RNA nucleotides located at the peptidyltransferase center. These insights are important for the future development of antibiotics that overcome such target protection resistance mechanisms

Longitudinal vibrations of underground pipelines of finite length in medium surrounded by soil with different properties along pipeline length

An analysis of the dynamic response of an underground main pipeline under a longitudinal wave propagating in soil along the pipe is given in the article. The problem of the longitudinal wave impact on a pipeline of finite length, interacting with soil according to the elastic-viscous law, is considered. The ends of the pipeline are fixed to massive nodes that interact with the medium according to linear laws. Along the length of the pipeline, the coefficients of the elastic and viscous pipeline-soil interaction change depending on the coordinate. In this article, the influence of the coefficients of elastic and viscous interaction of the "pipe-soil" system is studied when these coefficients are coordinate functions. The variability of the values of the coefficients along the length of the pipeline leads to a change in displacements from 0 to 15% and strain from 0 to 18%, compared with the case when these coefficients are constant. Depending on the length of the pipeline, the response of the pipeline to seismic action is different. This is especially evident at the boundary points. Considering the weight of nodes leads largely to a decrease in the strain of the pipeline relative to the soil strain at the boundary points

Calculation of insolation and KEO of the building information model

В данной диссертации был проведен анализ программных комплексов на рынке. В процессе работы проводились мероприятия по сбору и формализации требований к программному продукту, проектирование продукта, созданы дизайн макеты, на основе которых был реализован конкретный прикладной сервис. Разработанный сервис выполняет задачи расчета инсоляции и коэффициента естественной освещенности и соответствует современным требованиям по части проектирование пользовательского интерфейса.In this dissertation, an analysis of software systems on the market was carried out. In the process of work, activities were carried out to collect and formalize the requirements for a software product, product design, design layouts were created, on the basis of which a specific application service was implemented. The developed service performs the tasks of calculating insolation and daylight factor and meets modern requirements in terms of user interface design