Funktionelle Veränderungen bei operativer Behandlung der epiretinalen Gliose

With the increasing aging in our society, ERM represents one of the treatable causes of vi-sion impairment, especially in elderly people. Patients with ERM present with reduced and distorted vision, metamorphopsia, and nonspecific visual disturbances. The diagnosis of the ERM is based on clinical finding, mainly on a dilated fundus examination or fundus pho-tograph. A qualitative and quantitative analysis of the retina can nowadays be ob-tained using OCT cross-sectional images. ERM can be surgically well manageable with con-sequent reduction of metamorphopsia and improvement in vision. Despite all of the innovations in the field of vitreoretinal surgery, currently, there is not any possibility to capture the extent of the distortion, while other subjective testing methods such as visual acuity and central visual field, can be quantified. The study demonstrated that the new AMD® test can be used in clinical setting to detect and quantify the severity of metamorphopsia in patients with ERM. Moreover, a computer or mobile application for the AMD® test allows self-monitoring at home, which could strengthen the patient’s self-efficacy and has good promise of detecting metamorphopsia in the future. Especially taken into account the current situation with COVID-19 pandemic, when doctor visit is not alawys possible, in this case patients can monitor themselves at home and visit the ophthalmologist only when the score is changed. In this study, the degree and severity of metamorphopsia in patients with ERM pre- and postoperatively was quantified using the AMD® test. Results showed a significant and con-tinuous improvement in visual acuity and in metamorphopsia postoperatively. The metamorphopsia is a new clinical aspect, which could be used besides the visual acuity in observing operation outcomes and follow-up patients. To the best of our knowledge, no other studies have yet quantified the metamorphopsia using the AMD® test in patients with ERM. Larger studies with longer observation periods are crucial to evaluate the long-term morphological changes of metamorphopsia in patients with ERM.2021-04-0

Incidence of Chronic Myeloid Leukemia: Systematic Review and Meta-analysis

Background: To systematically assess and review the global incidence of Chronic Myeloid Leukemia using meta analyses and explore the factors associated with the variation of incidence of CML. Methods: Observational studies reporting CML from the globe were systematically searched in databases including MEDLINE (Ovid) and ProQuest. The author screened the studies and extracted data and assessed the risk of bias. Hoy’s risk of Bias tool was used to assess the biases in individual studies. Results: Seven studies reporting CML Incidence were included. pooled estimate of the CML incidence were 0.92 per 100,000 populations (95% CI: 0.70 – 1.22), Subgroup analysis shows no significant regional variation between Europe vs other country and global estimate. There was no trend when CML plotted over time. Conclusion: Given the pooled estimates vary widely with substantial heterogeneity, larger, well-designed studies especially in region and countries of developing world (Asia and Africa) are warranted to better understand the frequency and burden of CML

Thresholds Optimization for One-Bit Feedback Multi-User Scheduling

We propose a new one-bit feedback scheme with scheduling decision based on the maximum expected weighted rate. We show the concavity of the $2$-user case and provide the optimal solution which achieves the maximum weighted rate of the users. For the general asymmetric M-user case, we provide a heuristic method to achieve the maximum expected weighted rate. We show that the sum rate of our proposed scheme is very close to the sum rate of the full channel state information case, which is the upper bound performance

Contribution of refractory brick aggregates to improving the behavior of concrete subjected to high temperature

Today, the use of recycled aggregates as a substitute for natural aggregates in concrete production is an important process for sustainable concrete. Moreover, one of the most important processes of physical deterioration in the concrete structures is the exposure to high temperatures that influences their durability and stability during service life. This study aims, firstly, to investigate the possibility of using recycled refractory bricks (RBA) as coarse aggregate for concrete, and secondly, to find the ideal replacement percentage of coarse Natural Aggregate (NA) by RBA. Two types of RBA from two different sources were used, RBA-1 was obtained from the grinding of new refractory bricks and RBA-2 was obtained from refractory bricks used in the furnace recovered from the cement plant. When the optimum replacement percentage of coarse NA by RBA was finding, three types of concrete formulations were prepared: concrete made with 20% of coarse RBA-1, concrete made with 20% of coarse RBA-2 and concrete made with 20% of coarse and fine RBA-2. For each of the mentioned concrete families, three water/cement ratios (w/c = 0.59, 0.47 and 0.38) were used. All studied concretes were subjected to heating-cooling cycles of 150°C, 250°C, 400°C, 600°C and 800°C. After cooling down to ambient temperature, the following properties were evaluated and compared with conventional concretes made with 100% of coarse and fine NA: density, porosity, mass loss, change of volume, ultrasonic pulse velocity, damage degree, compressive strength and dynamic elastic modulus. Based on the experimental results obtained, it can be concluded that RBA is a potential alternative for natural aggregates in concrete manufacturing. Furthermore, concretes made with RBA show the best performance when subjected to high temperatures

Study on Self-healing Concrete types – A review

The most popular treatment for concrete structure is self-healing method to enhance the durability of concrete. The relevance between cracks and conceivable self-healing method is sophisticated and environmentally considered. This current paper a review on biological, natural and chemical mechanism of self-healing concrete was deeply evaluated from past journal was published about them and the main purposed of this paper as focuses on biological processes of self-healing concrete.  The data introduced in current study as huge substantial for bioprocess and biotechnologists engineer to provide useful details on present condition of self-healing concrete

Molecular characterization of bacteria isolated from the Kingdom of Saudi Arabia and their uses against pathogenic fungi causing dermatological diseases

Random amplified polymorphic DNA (RAPD) assay and antimicrobial activities were used for the detection of genetic variations of antimicrobial isolates from the Kingdom Saudi of Arabia. Soil samples were collected  from El-Madina El-Monawara, El–Taif, El-Jouf and El-Dammam for bacterial isolation. Bacterial isolates were  evaluated for their antimicrobial activities against pathogenic fungi which cause dermatological diseases;  Acremonium sp., Microsporium gypseum, Microsporium gallinae, Exserohilum sp., Trichphyton sp. and  Aspergillus niger. Results indicate that all the bacterial isolates showed different levels of antagonistic  activities against the pathogenic fungi. Esherichia coli M2, Bacillus megaterium M3 and Bacillus subtilis M10  showed strong effect against all the tested pathogenic fungi. B. subtilis J1 isolate showed strong effect against  the two pathogenic fungi M. gallinae and Exserohilum sp. Nine strains were tested for their antibiotic response. The results show that different antibiotic response was found. RAPD fingerprinting technique was applied to  study the genetic diversity among the tested strains. Results indicate that there was a significant genomic  diversity among the B. subtilis strains and this diversity was highly correlated with habitats and the  antagonistic effect of the studied strains.Key words: Random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR), bacterial isolates, pathogenic fungi, Kingdom of Saudi Arabia