THE INFLUENCE OF RETILINE ON THE IMMUNITY, HEMOSTASIS AND INSPECIFIC RESISTANCE WITH THE EYES DISEASES IN THE EXPERIMENT AND IN CLINIC

The object of investigation: the blood, lacrimal liquid, the eyes tissues of the experimental animals. The purpose of the work: studying the effect of retiline on the immunity, hemostasis and inspecific resistance of the organism: examining the effect of preparation on the course of the toxic and light distrophies, revealing the effect of retiline on the dynamics of the clinic and immunological indicators with the retina veins thromboses. The immunomodulating effect of the retina polypeptides, the intensification of the phagocytosis have been established. Retiline reduces the initially high aggregation of thrombocytes, intensifies the fibrinolysis. The application of retiline brings to the reduction of the reaction of the affection heaviness with the pathological processes in the retina. The medicinal preparation retiline has been used in treatment purpose. The results of treatment of the patients with the thromboses of the eyes vessels have been improvedAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

The role of neuron specific enolase for endocrine ophthalmopathy and the formation of optic neuropathy

Aim. The aim of this work was to study the role of the neuron specific enolase during the endocrine ophthalmopathy and the formation of optic neuropathy. Materials and methods. The study 42 patients with EOC at the age of 41 (30; 47) years. It was 9 males (21%). The control group consisted of 15 healthy individuals matched by sex and age. The object of the study of blood serum and tear fluid. Measurement of NSE level was measured by ELISA CanAgNSEEJA. All persons included in the study was performed optical coherence tomography (OCT), ophthalmoscopes, perimetry. Statistical analysis of the data using the program Statistics 6.1. Results. An increase in the concentration of NSE in serum and lachrymal fluid of patients with endocrine ophthalmopathy, compared to healthy subjects.  It should be noted that the increase in concentration of the test marker was associated with disease severity - more severe cases, accompanied by a large concentration of NSE. In severe IC-threatening loss of the highest concentration of NSE detected in blood serum and in the tear fluid. Conclusion. An increase in the concentration of NSE in patients with IC in the blood to a greater extent in the tear fluid, depending on the severity o f the IC. These studies allow the NSE to regard as an early marker of neuronal tissue damage GO, before the typical clinical and instrumental signs of optic neuropathy