90 research outputs found

    Online Library Package to Boost the Functionality and Usability of the Existing Libraries

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    The current computational era has given rise to the idea of the digital library. The essential purpose of digital libraries is to enable readers to more easily explore books for reading. The library is a fast-growing process. The prehistoric system of maintaining it is no longer efficient. Library staff handles tedious tasks which involve sorting, lending, returning, classification of books etc. In addition, library users encounter problems for searching, borrowing, renewing the book, queuing, and so on. To overcome these barriers, this paper proposes a smart E-library Application based on Android technology. It mainly focuses on the central operations in a Library like analyzing total books, calculating available books, updating information, searching books and a facility to request and return books. This Software package is an Android Application developed for android O.S based phones, intended to help users to maintain and organize Library Services. This software package is user-friendly. It will allow quick transactions and will make easy to handle the issue and return of books from the Library without much involvement of manual bookkeeping. This software has been developed to maintain all the daily work of the library. It has many features which are generally not available in normal library systems like facility of reader login and a facility of admin login. The admin can monitor the whole system

    Quantitative and Molecular Genetic Analyses of Mutations Increasing Drosophila Life Span

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    Understanding the genetic and environmental factors that affect variation in life span and senescence is of major interest for human health and evolutionary biology. Multiple mechanisms affect longevity, many of which are conserved across species, but the genetic networks underlying each mechanism and cross-talk between networks are unknown. We report the results of a screen for mutations affecting Drosophila life span. One third of the 1,332 homozygous P–element insertion lines assessed had quantitative effects on life span; mutations reducing life span were twice as common as mutations increasing life span. We confirmed 58 mutations with increased longevity, only one of which is in a gene previously associated with life span. The effects of the mutations increasing life span were highly sex-specific, with a trend towards opposite effects in males and females. Mutations in the same gene were associated with both increased and decreased life span, depending on the location and orientation of the P–element insertion, and genetic background. We observed substantial—and sex-specific—epistasis among a sample of ten mutations with increased life span. All mutations increasing life span had at least one deleterious pleiotropic effect on stress resistance or general health, with different patterns of pleiotropy for males and females. Whole-genome transcript profiles of seven of the mutant lines and the wild type revealed 4,488 differentially expressed transcripts, 553 of which were common to four or more of the mutant lines, which include genes previously associated with life span and novel genes implicated by this study. Therefore longevity has a large mutational target size; genes affecting life span have variable allelic effects; alleles affecting life span exhibit antagonistic pleiotropy and form epistatic networks; and sex-specific mutational effects are ubiquitous. Comparison of transcript profiles of long-lived mutations and the control line reveals a transcriptional signature of increased life span

    Plight of the pore polar bar(rier)

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    ROMK (Kir1.1) pharmacology comes of age

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    DESIGN AND ANALYSIS OF DOMESTIC REFRIGERATOR USING LPG CYLINDER

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    Supply of continuous electricity is still not available in several areas of the country and the world and refrigerator consuming more electricity. In this project we eliminate the problem of electricity. In this project using LPG as refrigerant we have design and analyze refrigerator. LPG is stored in cylinder at high pressure. As this pressurized LPG is passed through the capillary tube of small internal diameter, the pressure of LPG is decreased due to expansion and phase change of LPG occurs in an isenthalpic process. Due to phase change from liquid to gas latent heat of evaporation is gained by the liquid refrigerant and the temperature decreased. In this way LPG can produce refrigerating effect in the surrounding. After complete investigation we observed that the COP of LPG Refrigerator is higher than domestic Refrigerator

    A study comparing preoperative intra-incisional antibiotic infiltration and prophylactic intravenous antibiotic administration for reducing surgical site infection

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    Introduction: Surgical site infection (SSI) continues to be a distressing problem since time immemorial, as it happens to be one of the major causes of post-operative morbidity and mortality. Many methods have been evolved to combat wound infection, but the rate of wound infection has been more or less static over the past few decades. The search for alternative modes of management is going on and one of the methods is intra-incisional infiltration of antibiotics. Aims and Objectives: To study the comparative efficacy of pre-operative intra-incisional antibiotic infiltration and prophylactic parenteral antibiotic therapy in reducing surgical site infection. Materials and Methods: This is a prospective randomized controlled study comprising of 120 patients divided in to three groups i.e. 40 in each group. Group A comprising 40 patients were subjected to local infiltration of 1 gram of Cefotaxime around the site of incision, 20 min before the induction of anesthesia. Group B comprising of 40 patients were administered a single dose of 1 gram of Cefotaxime intravenously 20 minutes before the surgical incision and Group C comprising of 40 patients were administered local infiltration of 1 gram of Cefotaxime as well as intravenous administration of 1 gram of Cefotaxime, 20 minutes before surgical incision. Inclusion criteria were patients in age group of 20-60 yrs, procedures that lasted for less than 2 hours, clean and clean contaminated surgical procedures. The exclusion criteria were patients with diabetes mellitus and those on steroid therapy. Incidence of SSI, type of organisms cultured in case of infection were studied. Results: Overall incidence of SSI in Group A was 10%, in Group B 18%, and Group C 2.5%. Frequency of infection due to gram positive bacteria was more as compared to gram negative in the cases that developed SSI. The commonest organism isolated was Methicillin Sensitive Staphylococcus aureus (MSSA). Conclusion: The incidence of SSI was lower in the group of patients who were subjected to intra-incisional antibiotic infiltration as compared to the group who received prophylactic intravenous (IV) antibiotic. There was significant reduction in incidence of SSI in the group, which received both Intra-incisional as well as IV antibiotics. There was no definite correlation between the duration of surgery to the development of SSI in this study

    Design And Analysis Of Domestic Refrigerator Using Lpg Cylinder

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    Supply of continuous electricity is still not available in several areas of the country and the world and refrigerator consuming more electricity. In this project we eliminate the problem of electricity. In this project using LPG as refrigerant we have design and analyze refrigerator. LPG is stored in cylinder at high pressure. As this pressurized LPG is passed through the capillary tube of small internal diameter, the pressure of LPG is decreased due to expansion and phase change of LPG occurs in an isenthalpic process. Due to phase change from liquid to gas latent heat of evaporation is gained by the liquid refrigerant and the temperature decreased. In this way LPG can produce refrigerating effect in the surrounding. After complete investigation we observed that the COP of LPG Refrigerator is higher than domestic Refrigerator
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