Paradoxical Embolism in a Patient with Patent Foramen Ovale; a Case Report

Patent foramen ovale (PFO) is usually asymptomatic; however, it could be quite dangerous for patients with right side clot in which thrombus can transmit the PFO and paradoxically emboli to systemic circulation. Here we present a patient with ankle fracture and paradoxical embolus to the brain, who was successfully treated with emergent thrombectomy, inferior vena cava (IVC) filter placement and anticoagulation therapy. Despite the high rate of mortality in these patients, fortunately our patient survived with surgical treatment

Estimating Spray Characteristics of the Air-Blast atomizer of a Typical Jet Engine using Definition of the New Non-dimensional Number K: Numerical and Experimental Study

In this paper, by using a numerical solution and experiment investigation, a non-dimensional number is introduced to estimate the characteristics of a real engine airblast atomizer spray. This type of atomizers is usually used in airplain engines. The test is conducted in ambient atmospheric pressure and at 300 K temperature and the effects of pressure on atomizer flow rate and spray con angle are investigated. We used the discrete phase model and real information of the ALF502 engine for simulations and for boundary conditions respectively. Since the main application of this airblast atomizer is in aircraft engines and in the real working conditions, none of the pressure and flow rate parameters is constant, thus, the main aim of this research is to define a nondimensional number K, which considers the effects of working liquid flow rate, air flow rate and pressure on the droplets average diameter and spray con angle simultaneously. The results showed that, in general, with the increase of non-dimensional K number, the average diameter of droplets in primary and secondary break up increases, but spray con angle decreases. Furthermore, numerical solution results are compared with experiment results and 9.98% error was observed

Protective effects of Ceratonia siliqua extract on protamine gene expression, testicular function, and testicular histology in doxorubicin-treated adult rats: An experimental study

Background: Spermatogenesis is a complex process that takes place under the influence of many different genes. Objective: The aim of this study was to investigate the possible effects of Ceratonia siliqua hydroalcoholic extract (CSHAE) on protamine gene expression, testicular function, and testicular histology in doxorubicin-treated rats. Materials and Methods: 56 adult male rats with a age range of 2.5 to 3 months (210 ± 10 gr) were divided into seven groups (n = 8/each). A) Control group was left untreated; B) Sham group received 0.3 ml distilled water intraperitoneally, C) Negative control group received 3 mg/kg doxorubicin, intraperitoneally once a week for 28 days; and D) Positive control group received 600 mg/kg of CSHAE orally for 48 days; E, F, G) the experimental groups 1, 2, and 3 received 150, 300, and 600 mg/kg of CSHAE respectively orally, for 48 days, as well as 3 mg/kg doxorubicin once a week for 28 days. Hematoxylin-eosin staining was used in the histological study of testes, and enzyme-linked immunosorbent assay method was used in measuring serum levels of testosterone. Protamine gene expression was determined by real-Time PCR method. Results: The mean body weight, testicular weight, testicular volume, testosterone level (p = 0.022), the count of Leydig, spermatogonia, spermatocyte, and spermatid cells, as well as protamine gene expression (p = 0.008) were significantly increased in the experimental group 2 compared to the negative control group. The regeneration of testicular tissue was observed in the experimental group 2. Conclusion: CSHAE has protective effect on doxorubicin-induced testicular injuries. Key words: Ceratonia siliqua, Doxorubicin, Protamine, Testicular injuries, Rat

Assessment of Low-Level Laser Therapy Effects After Extraction of Impacted Lower Third Molar Surgery

Introduction: The aim of this study was to assess the effect of low-level laser therapy (LLLT) on pain, swelling and maximum mouth opening in patients undergoing third molar surgery.Methods: A prospective, randomized double-blind study was undertaken on 44 patients at the Dental School, Ahvaz Jundishapur University of Medical Sciences, in 2015. A low-level laser was randomly applied on one of the two sides after surgery of 15 patients. The experimental side received 18 J/cm2 of energy density, wavelength of 980 nm, and output power of 1.8 W. On the control side, a hand-piece was applied intra-orally, but laser was not activated. In addition, in order to evaluate trismus, 13 patients were treated by unilateral laser therapy and 16 patients did not receive laser therapy at all. The laser was administered intraorally on two points of vestibular and lingual sides at 1 cm from the surgery site, and extraorally at the emergence of the masseter muscle, immediately after surgery, and repeated 24 hours later. The pain, swelling and maximum mouth opening (MMO) were compared between the two groups at 24 hours and a week after surgery.Results: The mean score of pain 24 hours after surgery in the laser therapy group (2.3 ± 3.5) was significantly lower than the mean score of pain in the drug therapy (4.19 ± 3.09) (P = 0.036). Moreover, the mean score of pain at one week after surgery in the laser therapy group (0.13 ± 2.33) was significantly lower than the drug therapy group (1.43 ± 2.45) (P = 0.046). The amount of swelling according to different measurements did not significantly differ between the two groups neither at 24 hours nor at 1 week after surgery.Conclusion: Our findings showed that LLLT was useful in reducing pain and could slightly reduce swelling compared to drug therapy in impacted third molar surgery

Occurrence and Fate of Amoxicillin and Penicillin G Antibiotics in Hospital Wastewater Treatment Plants: A Case Study – Gonbad Kavous, Iran

Release of antibiotics to the environment as a result of wastewater effluent discharge is a cause for concern worldwide, as they pose a potential threat to  human health and the earth ecosystem. Penicillin and amoxicillin are widely used antibiotics. Despite their rapid hydrolysis in aqueous matrices, their  presence in the environment is widely investigated. The current study reported and analysed the current state of four hospital wastewater treatment  plants (WWTPs) in Gonbad Kavous, Iran, during 2019, from the perspective of amoxicillin and penicillin G removals. WWTPs were sampled at various  stages of the treatment process to determine at which stage the antibiotics are being removed. Concentrations of amoxicillin and penicillin G in raw  wastewater, analysed by HPLC, varied from 0.35 to 1.02 and 0.02–0.31 μgL−1, respectively. These values reduced in the final effluent, corresponding to  overall efficiency in removing the studied antibiotics of 20-60.5%. Anaerobic processes (i.e. septic tank) slightly outperformed aerobic biological processes  for both antibiotics’ removal, and penicillin G was removed more efficiently than amoxicillin. Effects of wastewater physicochemical properties,  including chemical oxygen demand (COD), biochemical oxygen demand (BOD), and total suspended solids (TSS) on antibiotics removal, were  also studied. Whereas statistically significant correlations were noticed between COD, amoxicillin and penicillin G removals, their decline showed no  correlation with TSS removal. Our study shows that despite the deployment of treatment plants, a considerable amount of antibiotics is released into  receiving water bodies, resulting in significant amounts of these pharmaceuticals entering the environment. There is abundant room for further progress  in the detection and quantification of pharmaceuticals and other emerging contaminants in hospital wastewaters and their metabolites and  biodegradation products.&nbsp

Effectiveness of Religious-Spiritual Group Therapy on Spiritual Health and Quality of Life in Methadone-treated Patients: A Randomized Clinical Trial

Background: Spirituality is one of the most important factors that can contribute to the recovery of substanceuse disorder (SUD). The objective of this study is to evaluate the efficacy of the religious-spiritual grouptherapy on the spiritual health and the quality of life in methadone-treated patients.Methods: This study was carried out in Qom City, Iran, in 2018. 72 methadone-treated patients wererandomly selected and assigned in two groups: the experimental group (which received religious-spiritualtherapy) and control group (which received no treatment). At the beginning of the study (pre-test), eightweeks after the start of the study (post-test), and three months after the start of the study (follow-up test), allparticipants completed the World Health Organization Quality of Life-BREF (WHOQOL-BREF)questionnaire and the Spiritual Well-Being Scale (SWBS). Participants in the experimental group received 8sessions (90 minutes for each session) of spiritual and religious training, while the control group received noreligious-spiritual intervention; it just was trained with general information on addiction. Data were analyzedusing SPSS software and descriptive and inferential statistics methods.Findings: The results of repeated measures analysis of variance (ANOVA) showed that there was nosignificant difference between the intervention and control groups in the pretest, but religious-spiritualtraining significantly increased spiritual health and the patients' quality of life (P < 0.001).Conclusion: Religious-spiritual education can improve the quality of life and spiritual well-being inmethadone-treated patients. The findings suggest that religious -spiritual education can be considered as aninexpensive, accessible, useful, and effective treatment for SUD treatmen

Social Alignment Contagion in Online Social Networks

Researchers have already observed social contagion effects in both in-person and online interactions. However, such studies have primarily focused on users’ beliefs, mental states, and interests. In this article, we expand the state of the art by exploring the impact of social contagion on social alignment, i.e., whether the decision to socially align oneself with the general opinion of the users on the social network is contagious to one’s connections on the network or not. The novelty of our work in this article includes: 1) unlike earlier work, this article is among the first to explore the contagiousness of the concept of social alignment on social networks; 2) our work adopts an instrumental variable approach to determine reliable causal relations between observed social contagion effects on the social network; and 3) our work expands beyond the mere presence of contagion in social alignment and also explores the role of population heterogeneity on social alignment contagion. Based on the systematic collection and analysis of data from two large social network platforms, namely, Twitter and Foursquare, we find that a user’s decision to socially align or distance from social topics and sentiments influences the social alignment decisions of their connections on the social network. We further find that such social alignment decisions are significantly impacted by population heterogeneity

The Effect of Peer Group-Based Training Using Health Belief Model on Quality of Life and Foot Ulcer Self-Care Behaviour in Patients with Type 2 Diabetes: A Randomized Controlled Clinical Trial

Objective: The present study was aimed at investigating the effect of peer group-based training (PGBT) using the health belief model (HBM) on the quality of life (QOL) and foot ulcer self-care behavior  in patients with type 2 diabetes. Materials and methods: The present study was a randomized controlled clinical trial performed on patients with type 2 diabetes who were referred to the Diabetic Care Clinic in Shiraz (Iran) from September 2019 to June 2020. A total of 70 patients participated in the study and were randomly assigned to peer training (n = 35) and control groups (n = 35). Diabetes Quality of Life, and diabetes self‑care behaviors, which were completed by both groups before, immediately, 1 month, and 3 months after the intervention. The data were analyzed using the Chi‑square test, paired t-test, independent t‑test, ANOVA, and descriptive statistical methods. P &lt; 0.05 was considered statistically significant. Results: The results showed that mean scores of QOL, constructs of HBM (awareness, perceived susceptibility, perceives severity, perceived benefit, self-care behavior, and foot care) before the intervention did not reveal a significant difference between the two groups, but immediately one month after the educational intervention, the mean values for the intervention group were significantly higher than the control group (p &lt; 0.05). Conclusions: PGBT using HBM was effective in increasing the mean score of QOL and self-care behavior in patients with type 2 diabetes. Thus, this method is recommended to be utilized alongside other methods to train patients

Effets du rapport des granulés de grains de blé et d'orge aux grains de maïs moulus dans l'alimentation sur les activités de tri et de mastication des vaches laitières soumises à un stress thermique

peer reviewedBackground Normal feeding behaviours is one of the criteria of the health condition of dairy cows particularly in the condition of heat stress. Objective The study evaluated the effects of the ratio of pellets of wheat and barley grains to ground corn grain on sorting activity and chewing behaviour of lactating dairy cows managed under ambient conditions including natural heat stress events. Materials and Methods Nine multiparous cows (650 ± 56 kg Body Weight; mean ± SD) averaging 102 ± 13 days in milk and producing 54 ± 6 kg/d were randomly assigned to a triplicate 3 × 3 Latin square. During each 21‐d period, cows received one of three total mixed rations as dietary treatments. The dietary treatments were three ratio of pellets (containing 50% ground wheat and 50% ground barley): ground corn on a dry matter (DM) basis: 1) 33.3:66.6 (low); 2) 66.6:33.3 (medium); and 3) 100:0 (high). During the experiment, the ambient temperature‐humidity index was equal or more than 72, indicating that the cows were predisposed to heat stress condition. Results Increasing the proportion of wheat‐barley pellets in the diet had a minimal effect on sorting index of different particles during the first 6 h of the day. However, later in the day (6‐18h), sorting against long particles (particles >19 mm) and in favour of fine particles (particles <1.18 mm) linearly increased with increasing the proportion of pellet; as a result overall daily sorting against long particles was increased with increasing the proportion of pellets. Although the average of daily eating and rumination was not affected by the treatments in the day times with high ambient THI, time spent for eating and rumination was low and eating time had more fluctuation for diet contained a high level of pellets. Conclusion Increasing the proportion of pellets of barley and wheat grains in the diet under conditions of heat stress caused more fluctuation in daily eating behaviour and cows were predisposed to sort against long particles