The relationship between emotional intelligence with general health and safety behavior among workers of a manufacturing industry in 2014-15

Background &amp; Objectives: One of the most important applications of psychological research is problem solving in the safety challenges field. Based on the role of emotional intelligence (EI) in mental health and prevention of unsafe behaviors, and to promote workforce's health, this study aimed to survey relationship between emotional intelligence with general health and safety behavior (BS) in an industry, in 2014. Materials &amp; Methods:In a descriptive-analytical and cross-sectional study, all operational employees working at a publication industry were included. Demographics, Goldberg general health-28, and Bradberry-Greaves questionnaires and a safety behavior checklist were tools to gather data. Statistical analysis of Pearson correlation was used to data evaluation by SPSS V22. Results: Mean EI test score was calculated which was equal to 122.2±15.7. Also, total score of staffs' general health was reported as 50.4±10.4. 646 out 800 of behaviors that were assessed in present study were safe (80.8). There was a significant relationship between EI (self-management component) and general health with correlation coefficient equal to -0.3. Also, depression with correlation coefficient equal to -0.334 was related to EI significantly (P<0.05). Further data revealed that there was significant and severe (0.8) relationship between EI (Social awareness component) with safe behaviors. Also, EI was not in significant relation with safety behavior (P<0.05). Conclusion:The findings of this study collectively indicated that subjects had not an acceptable situation for mental factors such as depression. However the results confirmed an essential role of EI in perceiving general health and preventing employees of negative behaviors. Based on this fact that education can improve EI, design an integrated package for EI development of employees was recommended strongly

Establishing self-help groups of women headed household in zone 17 of Tehran city, a step towards empowering women

زمینه و هدف: معضل بیکاری به عنوان یک مشکل اجتماعی اولویت دار در منطقه 17 شهرداری تهران است. از آنجا که وضعیت اشتغال زنان در ایران مانند بسیاری از کشورهای در حال توسعه، در وضعیت مطلوبی نیست، همواره زنان فرصت های شغلی کمتری دارند و غالباً در بخش غیـر رسمی با انـدک دستمزد مشغول بکارند این مداخله با هدف توانمندسازی زنان سرپرست خانوار و تشکیل گروههای خودیار به عنوان راهکار کوتاه مدت و عملی برای قشر آسیب پذیر زنان آن جامعه محلی انجام شد. روش بررسی: این مطالعه از نوع کیفی بوده و بر اساس پژوهش مشارکتی مبتنی بر جامعه انجام گرفت. جامعه مورد مطالعه در این پژوهش، 30 نفر از زنان سرپرست خانوار یا خود سرپرست ساکن در منطقه 17 شهرداری بودند که از طریق کمیته امداد، سازمان بهزیستی و سازمان تأمین اجتماعی شناسایی شدند. یافته ها: ضمن شناسایی زنان سرپرست خانوار و کلیه نهاد ها و سازمان های مرتبط به عنوان عوامل زمینه ساز جهت فراهم کردن فرصت ها برای زنان تحت مطالعه، ترغیب و جلب همکاری مستمر ذینفعان در فرآیند توانمندسازی حاصل گردید. نتیجه گیری: مشارکت دادن زنان سرپرست خانوار در تحلیل مسئله و یافتن راه حل مداخله ای برای رویارویی با این معضل اجتماعی منجر به توانمند شدن این زنان می گردد

Rapid Breast Cancer Disease Progression Following Cyclin Dependent Kinase 4 and 6 Inhibitor Discontinuation.

Background: CDK 4 and 6 inhibitors (CDK4/6i), which arrest unregulated cancer cell proliferation, show clinical efficacy in breast cancer. Unexpectedly, a patient treated on a CDK4/6i-based trial, as first-line therapy in metastatic breast cancer, developed rapid disease progression following discontinuation of study drug while receiving standard second-line therapy off trial. We thus sought to expand this observation within a population of patients treated similarly at The University of Texas MD Anderson Cancer Center. Methods: Using an IRB-approved protocol, 4 patients previously enrolled on CDK4/6i trials were analyzed for outcomes after discontinuing study drug. These patients were treated on a randomized trial of first-line endocrine therapy +/- a CDK4/6i. Rapid disease progression was defined as progression occurring within 4 months of CDK4/6i discontinuation. Results: In total, 4 patients developed rapid disease progression and died; 2 of whom died within 6 months of CDK4/6i discontinuation. Conclusion: This case series suggests a potential for rapid disease progression following CDK4/6i discontinuation. However, the clinical course following progression must be validated in large CDK4/6i clinical trials and standard-of-care cohorts. If confirmed, such observations may alter the algorithm for subsequent therapy in patients with disease progression on CDK4/6i. Nevertheless, the need remains to define a mechanistic basis for this rapid progression and formulate alternative therapeutic strategies

Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer

In our previous work we showed that NGAL, a protein involved in the regulation of proliferation and differentiation, is overexpressed in human breast cancer (BC) and predicts poor prognosis. In neoadjuvant chemotherapy (NACT) pathological complete response (pCR) is a predictor for outcome. The aim of this study was to evaluate NGAL as a predictor of response to NACT and to validate NGAL as a prognostic factor for clinical outcome in patients with primary BC. Immunohistochemistry was performed on tissue microarrays from 652 core biopsies from BC patients, who underwent NACT in the GeparTrio trial. NGAL expression and intensity was evaluated separately. NGAL was detected in 42.2% of the breast carcinomas in the cytoplasm. NGAL expression correlated with negative hormone receptor (HR) status, but not with other baseline parameters. NGAL expression did not correlate with pCR in the full population, however, NGAL expression and staining intensity were significantly associated with higher pCR rates in patients with positive HR status. In addition, strong NGAL expression correlated with higher pCR rates in node negative patients, patients with histological grade 1 or 2 tumors and a tumor size <40 mm. In univariate survival analysis, positive NGAL expression and strong staining intensity correlated with decreased disease-free survival (DFS) in the entire cohort and different subgroups, including HR positive patients. Similar correlations were found for intense staining and decreased overall survival (OS). In multivariate analysis, NGAL expression remained an independent prognostic factor for DFS. The results show that in low-risk subgroups, NGAL was found to be a predictive marker for pCR after NACT. Furthermore, NGAL could be validated as an independent prognostic factor for decreased DFS in primary human BC

A figura da mulher na poesia turca com base em materiais didáticos

In Turkish poetry, the figure of women is important in university curricula. The images of women in the examples shown to students in the taught literary texts are also important in mastering the subject. Since ancient times, woman figure has been one of the most widely used figures in the Turkish literature. We meet women as a lover, a mother and a sister in the works of poets and writers for centuries. In classical poetry, the woman figure has been developed more as a symbol of beauty. When describing the beauty of a woman, the representatives of the Divan literature compared it with the beauties of nature and often equated them with various elements of nature. The value given to women began to change over the period of Turkish literature formed under the influence of the West. Poets and writers are already expressing their views on the role of women in social life and address the problems faced by women.En la poesía turca, la figura de la mujer es importante en los planes de estudios universitarios. Las imágenes de mujeres en los ejemplos mostrados a los estudiantes en los textos literarios enseñados también son importantes para dominar el tema. Desde la antigüedad, la figura de la mujer ha sido una de las figuras más utilizadas en la literatura turca. Encontramos mujeres como amantes, madres y hermanas en las obras de poetas y escritores durante siglos. En la poesía clásica, la figura de la mujer se ha desarrollado más como símbolo de belleza. Al describir la belleza de una mujer, los representantes de la literatura Divan la compararon con las bellezas de la naturaleza y, a menudo, las equipararon con varios elementos de la naturaleza. El valor otorgado a las mujeres comenzó a cambiar durante el período de la literatura turca formada bajo la influencia de Occidente. Los poetas y escritores ya están expresando sus puntos de vista sobre el papel de la mujer en la vida social y abordan los problemas que enfrentan las mujeres.Na poesia turca, a figura da mulher é importante nos currículos universitários. As imagens de mulheres nos exemplos mostrados aos alunos nos textos literários ensinados também são importantes para o domínio do assunto. Desde os tempos antigos, a figura da mulher tem sido uma das figuras mais utilizadas na literatura turca. Conhecemos as mulheres como amante, mãe e irmã nas obras de poetas e escritores ao longo dos séculos. Na poesia clássica, a figura da mulher desenvolveu-se mais como um símbolo de beleza. Ao descrever a beleza de uma mulher, os representantes da literatura Divan a compararam com as belezas da natureza e muitas vezes as equipararam a vários elementos da natureza. O valor dado às mulheres começou a mudar ao longo do período da literatura turca sob a influência do Ocidente. Poetas e escritores já expressam suas opiniões sobre o papel da mulher na vida social e abordam os problemas enfrentados pelas mulheres

Exploring Viscophoresis

The diffusion of a Brownian particle is governed by the viscosity of the medium, exerting a viscous friction force that damps the instantaneous fluctuations in the particle's dynamics. Within the framework of viscophoresis theory, an inhomogeneous medium subjected to a viscosity gradient induces Brownian particles to migrate towards regions of lower viscosity to obtain higher diffusivity. In the present study, we aimed to provide experimental evidence for this phenomenon at a nuanced, particle-level insight. Employing a microfluidic gradient generator, we successfully introduced a controlled and highly stable viscosity gradient within a defined shallow microchannel. Furthermore, we directly and accurately measured the induced drift velocity and the associated diffusivity gradient in response to the introduced viscosity gradient using a super-resolution fluorescence microscope. Our experimental data interestingly confirmed the existence of viscophoretic drift velocity, but this velocity was found to significantly exceed theoretical expectations. We believe this discrepancy may stem from the fact that larger particles experience a pronounced difference in diffusivity due to their size, a detail that current theoretical models do not adequately consider. Furthermore, we conducted a comprehensive investigation into the interplay between viscophoresis and diffusiophoresis, highlighting potential applications such as trapping and concentrating particles. Our comprehensive exploration of viscophoresis in this study stands to greatly enhance both understanding and application of transport processes influenced by viscosity gradients, with broad implications across diverse scientific fields including cell biology, chromatography, and membrane technology

Exploring Viscophoresis

The diffusion of a Brownian particle is governed by the viscosity of the medium, exerting a viscous friction force that damps the instantaneous fluctuations in the particle's dynamics. Within the framework of viscophoresis theory, an inhomogeneous medium subjected to a viscosity gradient induces Brownian particles to migrate towards regions of lower viscosity to obtain higher diffusivity. In the present study, we aimed to provide experimental evidence for this phenomenon at a nuanced, particle-level insight. Employing a microfluidic gradient generator, we successfully introduced a controlled and highly stable viscosity gradient within a defined shallow microchannel. Furthermore, we directly and accurately measured the induced drift velocity and the associated diffusivity gradient in response to the introduced viscosity gradient using a super-resolution fluorescence microscope. Our experimental data interestingly confirmed the existence of viscophoretic drift velocity, but this velocity was found to significantly exceed theoretical expectations. We believe this discrepancy may stem from the fact that larger particles experience a pronounced difference in diffusivity due to their size, a detail that current theoretical models do not adequately consider. Furthermore, we conducted a comprehensive investigation into the interplay between viscophoresis and diffusiophoresis, highlighting potential applications such as trapping and concentrating particles. Our comprehensive exploration of viscophoresis in this study stands to greatly enhance both understanding and application of transport processes influenced by viscosity gradients, with broad implications across diverse scientific fields including cell biology, chromatography, and membrane technology

Smart passive adaptive control of laminated composite plates (through optimisation of fibre orientation)

In the classical laminate plate theory for composite materials, it is assumed that the laminate is thin compared to its lateral dimensions and straight lines normal to the middle surface remain straight and normal to the surface after deformation. As a result, the induced twist which is due to the transverse shear stresses and strains are neglected. Also, this induced twist was considered as an unwanted displacement and hence was ignored. However, in certain cases this induced twist would not be redundant and can be a useful displacement to control the behaviour of the composite structure passively. In order to use this induced twist, there is a need for a modified model to predict the behaviour of laminated composites. A composite normally consists of two materials; matrix and fibres. Fibres can be embedded in different orientations in composite lay-ups. In this research, laminated composite models subject to transfer shear effect are studied. A semi analytical model based on Newton-Kantorovich-Quadrature Method is proposed. The presented model can estimate the induced twist displacement accurately. Unlike other semi analytical model, the new model is able to solve out of plane loads as well as in plane loads. It is important to mention that the constitutive equations of the composite materials (and as a result the induced twist) are determined by the orientation of fibres in laminae. The orientation of composite fibres can be optimised for specific load cases, such as longitudinal and in-plane loading. However, the methodologies utilised in these studies cannot be used for general analysis such as out of plane loading problems. This research presents a model whereby the thickness of laminated composite plates is minimised (for a desirable twist angle) by optimising the fibre orientations for different load cases. In the proposed model, the effect of transverse shear is considered. Simulated annealing (SA), which is a type of stochastic optimisation method, is used to search for the optimal design. This optimisation algorithm is not based on the starting point and it can escape from the local optimum points. In accordance with the annealing process where temperature decreases gradually, this algorithm converges to the global minimum. In this research, the Tsai-Wu failure criterion for composite laminate is chosen which is operationally simple and readily amenable to computational procedures. In addition, this criterion shows the difference between tensile and compressive strengths, through its linear terms. The numerical results are obtained and compared to the experimental data to validate the methodology. It is shown that there is a good agreement between finite element and experimental results. Also, results of the proposed simulated annealing optimisation model are compared to the outcomes from previous research with specific loading where the validity of the model is investigated