Molecular epidemiology of Rotavirus in children with gastroenteritis in Qatar

Acute gastroenteritis remains a major cause of morbidity and mortality of young children worldwide. The vast majority of diarrhea cases in developing and developed countries are attributable to the viruses and to a lesser extent to bacteria, fungi and toxins. Rotavirus (RV) is recognized as the most important etiological agent leading to acute gastroenteritis globally. In order to determine the burden and characteristics of RV infections in children in Qatar, profiling of circulating genotypes and their correlation with demographics and clinical manifestations were evaluated

Global Prevalence of Tobacco Use in Adolescents and Its Adverse Oral Health Consequences

BACKGROUND: Smoking is associated with various systemic conditions and contributes to a huge financial burden to economies around the world. AIM: The study aimed to evaluate global data about the prevalence of tobacco use among male and female adolescents and to discuss smoking-related oral complications. METHODS: The prevalence data of tobacco use among adolescents (13-15 years) was retrieved from the World Health Organization (Global Health Observatory). The World Bank’s statistics about gross national income (GNI) per capita were used to categorise low-income, lower-middle-income, upper-middle-income, and high-income countries. PubMed, Web of Science, Scopus, and Embase databases were searched to gather updated evidence about the adverse consequences of smoking on oral health among adolescents. RESULTS: The prevalence of tobacco use was 19.33%, and there were 23.29% of male and 15.35% female smoker adolescents in 133 countries (p < 0.001). The highest prevalence of tobacco use in male (24.76%) and female (19.4) adolescents was found in high-income countries. Significantly higher proportions of male adolescents were smokers than female counterparts in low-income, lower-middle-income, and upper-middle-income (p < 0.001). However, there were no statistically significant differences in tobacco use between male and female adolescents in high-income countries. Low-income countries had the lowest prevalence (14.95%) of tobacco use, while high-income countries had the highest prevalence estimates (22.08). Gingivitis (72.8%), gingival bleeding (51.2%), oral malodor or halitosis (39.6%) is common oral conditions among smoker adolescents. Smoking habit is significantly associated with dental caries, periodontal disease, hairy tongue, smoking-related melanosis, and hyperkeratosis among adolescents. CONCLUSION: There was a high prevalence of tobacco use among male and female adolescents around the globe. Available evidence suggests a strong association between smoking and compromised oral health among adolescents. Globally, measures should be taken to prevent and control the menace of tobacco use to reduce systemic and oral complications

More than ten years of Blockchain creation: How did we use the technology and which direction is the research heading?

To identify how blockchain technology affects current and future research, we carried out a bibliometric overview of the journal articles written on the blockchain. We aimed to answer some of the questions to visualize the trend of the publications regarding the advancement of blockchain utilization in fields relating to finance, economics, and social science. We used the Scopus database for the literature research, which resulted in 506 papers by 1278 authors from 79 countries. Our study showed that from 2008 till 2021, publishing about blockchain was more significant in conference papers than articles by a factor of 2. Our study also showed the importance of citation regarding published academic articles, the link to the number of publications, the authors, the universities, the affiliated organizations, and the countries of the publications. The use of authoring and citation analysis give valuable insights. On the topic of blockchain, we identified Financial Innovation as the most impactful journal on the topic, the National Natural Science Foundation of China as the leading funding sponsor on blockchain research, the USA as the highest publication production country, and Hong Kong as the highest country in the average citation per document produced. We finally identified the 20 most cited articles on the blockchain topics. Unlike other brief bibliometric studies, our study's investigation and findings could become a first stage of learning for those interested in carrying out a bibliometric study. In addition, our study could become the starting point for any future research on any blockchain projects

Antimicrobial activity of Dracaena cinnabari resin from Soqotra Island on multi drug resistant human pathogens

Background: Few studies showed that Dracaena cinnabari resin, collected from Soqotra Island,  Yemen,  has antimicrobial activity. This study is the first to investigate antimicrobial activity of the resin on both antibiotic multi-resistant human pathogens and on poly-microbial culture.Material and Methods: Antimicrobial activity of ethanolic extract of Dracaena cinnabari resin from  Soqotra Island on multidrug resistant Gram-positive and Gram-negative human ATCC standard pathogens  and Ascosphaera apis, the causal organism of chalkbrood disease of honeybee was studied using the agar disc diffusion method. The minimal inhibitory concentration of extracts was carried out by  the broth micro dilution method.Results: Ethanolic extract of Dracaena cinnabari resin showed a considerable antimicrobial activity  against all the pathogens tested. The zone of inhibition were between 4.9-11.5 mm. The most sensitive  microbe was Staphylococcus aureus and least sensitive was Aspergillus nidulans. The minimal inhibitory concentration of the extract against Escherichia. coli ATCC 10402, Klebsiella pneumonia ATCC 10031, and Staphylococcus aureus ATCC 29212 was 1.25 μg/mL (w/v) and for the other pathogens (Candida albicans ATCC 10231, Salmonella typhimurum ATCC 3311 and Pseudomonos aeruginosa ATCC 2785) was 2.5 μg/mL (w/v).Conclusion: Ethanolic extract of Dracaena cinnabari resin has a considerable antimicrobial activity  against Gram-positive and Gram-negative human pathogens and fungi. This extract might possess a role in the management of microbial infections in human and honeybee disease.Key words: Antimicrobial Activity, Dracaena cinnabari, Human pathogens, Minimum Inhibitory Concentratio

Prevalence, Comparison, and Determinants of Smoking among Young Schoolchildren in Kingdom of Saudi Arabia

BACKGROUND: Smoking is one of the most serious health issues among all age groups, particularly in children globally including the Gulf region. However, there are little data about the prevalence in public and private schools and determinants of smoking among adolescents in Saudi Arabia. AIM: The purpose of this study was to estimate the prevalence, compare, and determine smoking habits among male children in public and private schools. METHOD: This cross-sectional study was conducted in Dammam city, KSA. The data were collected from 866 male children studying in public and private schools. Sample was calculated through stratified random sampling. The modified “Global Youth Tobacco Survey (GYTS)” was used to collect information. RESULTS: The total number of children recruited was 866 (223 from private and 643 from public schools). The mean age of children studied was 14.20 ± 1.03 years in both groups. The result shows that overall 27.8% of children tried to smoke cigarette both in public and private schools. The prevalence of smoking is higher in public schools’ children than in private schools (30% vs. 21%; p = 0.005). In addition, wrong perception of comfortable feeling after smoking, easy access to cigarettes, parent’s addiction, and smoking in front of children are the determining factors. CONCLUSION: This study suggests that the prevalence of cigarettes smoking among children exists in considerable proportion. It is higher in public schools children. The health and education authorities should take urgent steps to encounter this major health issue

Types of glaucoma in a university health centre in Al‑Ahsa, Saudi Arabia: a pilot study

Objective: The objective was to assess the profile of different types of glaucoma in a University Health Centre in Al‑Ahsa, Saudi Arabia.Materials and Methods: It is a retrospective study in which the files of the patients at King Faisal University Health Centre were reviewed. The data collected included: Age, sex, race, visual acuity, the slit lamp examination findings, the intraocular pressure (IOP) as the average of 3 readings, the cup‑to‑disc ratio (CDR), the visual field changes, and the details of treatment received.Results: Eighty glaucomatous eyes from 50 patients were included in the study. The mean age was 54.8 ± 12.7 years, and the mean IOP was 19 ± 3.9 mmHg that ranged from 11 to 28 mmHg. The mean CDR mean was 0.48 ± 0.16 that ranged between 0.3 and 0.9. Ninety‑one percent of the visual field defects were arcuate scotomata. Primary open‑angle glaucoma (POAG) (60%) was the most predominant type of glaucoma, followed by primary angle closure glaucoma (ACG) (21.3%), secondary OAG (7.5%), and secondary ACG (6.3%). As for the anti‑glaucoma medications, 88% of the studied patients were on more than one medicine.Conclusion: This pilot study has demonstrated that POAG may be the predominant type of glaucoma in Al‑Ahsa, Kingdom of Saudi Arabia (KSA). Apopulation‑based study with a larger sample size is warranted to confirm the outcome and to provide a baseline data on the prevalence of types of glaucoma in this region of KSA.Keywords: Glaucoma, glaucoma types, prevalence, Saudi Arabi

Short-, Medium-, and Long-Term Prediction of Carbon Dioxide Emissions using Wavelet-Enhanced Extreme Learning Machine

Carbon dioxide (CO2) is the main greenhouse gas responsible for global warming. Early prediction of CO2 is critical for developing strategies to mitigate the effects of climate change. A sophisticated version of the extreme learning machine (ELM), the wavelet enhanced extreme learning machine (W-EELM), is used to predict CO2 on different time scales (weekly, monthly, and yearly). Data were collected from the Mauna Loa Observatory station in Hawaii, which is ideal for global air sampling. Instead of the traditional method (singular value decomposition), a complete orthogonal decomposition (COD) was used to accurately calculate the weights of the ELM output layers. Another contribution of this study is the removal of noise from the input signal using the wavelet transform technique. The results of the W-EELM model are compared with the results of the classical ELM. Various statistical metrics are used to evaluate the models, and the comparative figures confirm the superiority of the applied models over the ELM model. The proposed W-EELM model proves to be a robust and applicable computer-based technology for modeling CO2concentrations, which contributes to the fundamental knowledge of the environmental engineering perspective. Doi: 10.28991/CEJ-2023-09-04-04 Full Text: PD

Memokath for treating ureteric stricture post cryoablation of renal mass: a case report of rare complication and proposed alternative management

The use of cryoablation in the management of small renal masses is widely acceptable. Although rare but ureteral injury during the procedure with subsequent stricture formation can result in devastating effects on renal function. On the other hand, the management of such strictures requires reconstructive surgery as gold standard. Unfortunately, in some cases the reconstructive surgery might not be feasible, and the treatment usually is ureteral stent insertion that need to be changed regularly. Here we present a case of a 53-year-old gentleman who developed an upper ureteric iatrogenic stricture post cryoablation in which the reconstructive surgery was not feasible due to high procedural risk. We used metallic ureteral stent (Memokath) instead of regular ureteral double J stent. We found that if the reconstructive surgery is not possible the usage of Memokath in treating iatrogenic ureteral strictures is associated with better quality of life, lower costs and a similar functional outcome when compared to ureteral double J stent that needs regular frequent changes

Gastro-oesophageal reflux is not a major cause of brief resolved unexplained events in infants

The clinical scenario of an infant presenting to the emergency department with the parents reporting a history of the child stopping breathing, choking or “turning blue” at home is a well-recognised event and accounts for between 2.5 and 4.1 hospital admissions per 1000 live births [1, 2]. The infant is often back to their normal self with a normal clinical examination. This event used to be called an apparent life-threatening event (ALTE) [1] and recently it has been suggested that it should now be called a brief resolved unexplained event (BRUE) [2]. Gastro-oesophageal reflux (GOR) has long been considered to be a common reason for an ALTE and some studies have listed it as an underlying cause in up to 54% of patients [3–6]. Does the evidence support this belief