Do Xylylenes Isomerize in Pyrolysis?

Contains fulltext : 221459.pdf (publisher's version ) (Open Access

Do Xylylenes Isomerize in Pyrolysis?

Contains fulltext : 221459.pdf (publisher's version ) (Open Access

Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication

Microscopic imaging and technolog

Clinical and laboratory findings in five patients with Guillain-Barré syndrome from whom <i>Campylobacter jejuni</i> was isolated and used in the current study^a.

<p>a. Abbreviations: M, Male; F, Female; +, present; -, absent; N, normal, GBS disability score (6).</p

Serum samples from patients with GBS and from controls with other neurological disease (OND) and family controls (FC) were tested for IgG activity to lipo-oligosaccharides (LOS) from 6 <i>C. jejuni</i>.

<p>Subcharts represent serum IgG activity to LOS from (<b>A</b>) <i>C. jejuni</i> BD-07 isolated from a GBS patient (<b>B</b>) <i>C. jejuni</i> BD-39 isolated from a GBS patient, (<b>C</b>) <i>C. jejuni</i> BD-10 isolated from a GBS/MFS patient, (<b>D</b>) <i>C. jejuni</i> BD-67 isolated from a GBS/MFS patient, (<b>E</b>) <i>C. jejuni</i> BD-94 isolated from a GBS patient (<b>F</b>) <i>C. jejuni</i> Penner HS:03 serostrain (CCUG 10937), lacking ganglioside mimics, as a control. *p<0.001. Lines () indicate cut-off value. GBS, Guillain-Barré syndrome; OND, other neurological disease; FC, family controls; LOS, lipo-oligosaccharides.</p

Proposed LOS outer core structures based on capillary-electrophoresis electrospray ionization mass spectrometry analysis of <i>O</i>-deacylated LOS samples (see Table S1).

<p>(A) strains BD-07 and BD-39 show mimicry with GM1 and GD1a; (B) strains BD-10 and BD-67 show mimicry with GA2 and GD3. Terminal regions mimicking gangliosides are indicated with arrows.</p

Binding of mouse monoclonal antibodies against LOS from <i>C. jejuni</i> BD-07 and BD-39.

<p>DG-1 (binding to GM1), TBG-3 (binding to GD1a), EG-7 (binding to GD1b), EG-3 (binding to GQ1b) and EG-1 (binding to GQ1b/GT1a).</p

Clinical characteristics of GBS patients associated with presence IgM and/or IgG antibodies in serum to the gangliosides GM1, GD1a and GQ1b^*.

*<p>Data were expressed as median or number of patients (percentage); M, male; F, female; CI, confidence interval; – cannot be calculated.</p>†<p>Determined by Chi-square or Fisher’s exact test.</p>¶<p>Determined by Wilcoxon-Mann-Whitney <i>U</i> test.</p>‡<p>Axonal variants: acute motor axonal neuropathy (AMAN), acute motor sensory axonal neuropathy (AMSAN).</p>§<p>AIDP, acute inflammatory demyelinating polyneuropathy.</p

Going large(r): general discussion

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