23 research outputs found
The de novo FAIRification process of a registry for vascular anomalies
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An Ontological Approach to Inform HMI Designs for Minimizing Driver Distractions with ADAS
ADAS (Advanced Driver Assistance Systems) are in-vehicle systems designed to enhance driving
safety and efficiency as well as comfort for drivers in the driving process. Recent studies have
noticed that when Human Machine Interface (HMI) is not designed properly, an ADAS can cause
distraction which would affect its usage and even lead to safety issues. Current understanding of
these issues is limited to the context-dependent nature of such systems. This paper reports the
development of a holistic conceptualisation of how drivers interact with ADAS and how such
interaction could lead to potential distraction. This is done taking an ontological approach to
contextualise the potential distraction, driving tasks and user interactions centred on the use of
ADAS. Example scenarios are also given to demonstrate how the developed ontology can be used
to deduce rules for identifying distraction from ADAS and informing future designs
MozaĂŻek woningmarkt stadsregio Rotterdam. Dl. 2. Woningbehoefteprognoses, een vergelijkende analyse van modellen en methoden
OTB Research Institute for the Built Environmen
Measurement of housing preferences: A comparison of research activity in the Netherlands and Finland
Increased affluence and individual lifestyles have widely spread across western countries in recent decades. We expect this development to coincide with the use of more qualitative and more disaggregated research methods (the so called Mode 2 research methods) because these tools enable coping with a growing diversity of housing preferences. However, the usefulness of this partial explanation remains embedded in power relationships among relevant actors; theoretically also the infl uence of politicians, researchers and the building industry can explain this outcome. A successful diffusion of research methods depends on the research interest of all relevant actors (science, policy, consumption or industrydriven agenda) in relation to the target housing market characteristics (quantitative or qualitative perspective). An empirical investigation of two countries: Finland and the Netherlands, shows some striking parallels in this respect but also some significant differences.OT
Natural language processing algorithms for mapping clinical text fragments onto ontology concepts: a systematic review and recommendations for future studies
Background: Free-text descriptions in electronic health records (EHRs) can be of interest for clinical research and care optimization. However, free text cannot be readily interpreted by a computer and, therefore, has limited value. Natural Language Processing (NLP) algorithms can make free text machine-interpretable by attaching ontology concepts to it. However, implementations of NLP algorithms are not evaluated consistently. Therefore, the objective of this study was to review the current methods used for developing and evaluating NLP algorithms that map clinical text fragments onto ontology concepts. To standardize the evaluation of algorithms and reduce heterogeneity between studies, we propose a list of recommendations. Methods: Two reviewers examined publications indexed by Scopus, IEEE, MEDLINE, EMBASE, the ACM Digital Library, and the ACL Anthology. Publications reporting on NLP for mapping clinical text from EHRs to ontology concepts were included. Year, country, setting, objective, evaluation and validation methods, NLP algorithms, terminology systems, dataset size and language, performance measures, reference standard, generalizability, operational use, and source code availability were extracted. The studiesâ objectives were categorized by way of induction. These results were used to define recommendations. Results: Two thousand three hundred fifty five unique studies were identified. Two hundred fifty six studies reported on the development of NLP algorithms for mapping free text to ontology concepts. Seventy-seven described development and evaluation. Twenty-two studies did not perform a validation on unseen data and 68 studies did not perform external validation. Of 23 studies that claimed that their algorithm was generalizable, 5 tested this by external validation. A list of sixteen recommendations regarding the usage of NLP systems and algorithms, usage of data, evaluation and validation, presentation of results, and generalizability of results was developed. Conclusion: We found many heterogeneous approaches to the reporting on the development and evaluation of NLP algorithms that map clinical text to ontology concepts. Over one-fourth of the identified publications did not perform an evaluation. In addition, over one-fourth of the included studies did not perform a validation, and 88% did not perform external validation. We believe that our recommendations, alongside an existing reporting standard, will increase the reproducibility and reusability of future studies and NLP algorithms in medicine
The de novo FAIRification process of a registry for vascular anomalies
Background: Patient data registries that are FAIRâFindable, Accessible, Interoperable, and Reusable for humans and computersâfacilitate research across multiple resources. This is particularly relevant to rare diseases, where data often are scarce and scattered. Specific research questions can be asked across FAIR rare disease registries and other FAIR resources without physically combining the data. Further, FAIR implies well-defined, transparent access conditions, which supports making sensitive data as open as possible and as closed as necessary. Results: We successfully developed and implemented a process of making a rare disease registry for vascular anomalies FAIR from its conceptionâde novo. Here, we describe the five phases of this process in detail: (i) pre-FAIRification, (ii) facilitating FAIRification, (iii) data collection, (iv) generating FAIR data in real-time, and (v) using FAIR data. This includes the creation of an electronic case report form and a semantic data model of the elements to be collected (in this case: the âSet of Common Data Elements for Rare Disease Registrationâ released by the European Commission), and the technical implementation of automatic, real-time data FAIRification in an Electronic Data Capture system. Further, we describe how we contribute to the four facets of FAIR, and how our FAIRification process can be reused by other registries. Conclusions: In conclusion, a detailed de novo FAIRification process of a registry for vascular anomalies is described. To a large extent, the process may be reused by other rare disease registries, and we envision this work to be a substantial contribution to an ecosystem of FAIR rare disease resources