A Survey of the Benthic Macroinvertebrates of the Big Spring Basin, Iowa

Benthic macroinvertebrates were collected in the Big Spring Basin, located in northeastern Iowa, from May through October 1988. The purpose of the study was to develop baseline information on the benthic organisms present in the basin. A total of 167 taxa including seven species of leeches, five genera of snails, three genera of clams, one crayfish genus and over 150 taxa of aquatic insects were identified with the majority of the organisms having been reported in Iowa previously. Benthic organisms not usually encountered in Iowa include the planarian, Cura formanii; the isopod, Lirceus; the beedes, Enrxhrus, Hydrophilus, and llybius; the chironomids, Diamesa and Prodiamesa; the mayfly, Stenacron candidum; the damselfly, Archilestes grandis; the dragonfly, Aeshna tuberculifera; the sconefly, Claassenia and the caddisfly, Helicopsyche borealis. The variety and distribution of benthic organisms within the Big Spring Basin reflect the numerous habitats in the various stream segments. Many of the benthic organisms collected, especially chose not reported before, are known to prefer clear, cold water streams such as those found in the Big Spring Basin. The continued existence of this aquatic life is dependent upon, at a minimum, maintaining current water quality conditions in the basin

A Statewide Screening For Acid Rainfall In Iowa

From April through October 1980, a statewide screening for acid rainfall was conducted in Iowa. Ninety-seven National Weather Service observers were provided with pH color-indicating strips and measured and recorded the pH of every precipitation sample. Results of the screening indicate pH values of rainfall ranged from a low of 4.0 to a high of 7.0. The pH values 5.7 and 5.9 were observed most often and represented 66% of the 4,197 values measured. Approximately 80% of the rainfall pH values fell in the 5.7 to 7.0 range and 20% in the acid rainfall range (5.6 or less). Median pH values calculated for the 97 sampling locations ranged from 5.1 to 6.2, with medians of 5.7 and 5.9 occurring most frequently. With the exception of one 3-county area, most of the 11 sampling locations demonstrating acid rainfall (median values 5.6 or less) were widely separated and probably represented localized problems. Three adjacent counties located in southeast Iowa had low median pH values and this area is recommended for future study

The Grizzly, November 10, 1978

Physical Education Program To Change • Task Force Continues Recommendations • No Funds For Bomberger • Forum: High Strung • Hockey Not Safe • Staffer Clears Misinterpretation • Dining Service Transitions • Letters to the Editor • Portrait of the Professor: Gayle A. Byerly • For Whom The Walls Toil • Egdon Heath - A New Look For Monday Night • The Good Doctor Makes House Call To Protheatre • Eighteen Named to Who\u27s Who • Free V. D. Clinic • GM: Looking Good For \u2779 • Sports Profile: Keith Kemper • Thinclads Nab Third At MAC\u27s • Soccer Kicks Moravian • Bears Blast Dickinson • Gymnastics Get New Coach • Hockey Ends • Women\u27s B-Ball Preview • News in Brief: Senior Symposium Cancelled; Deans Attend State Conventionhttps://digitalcommons.ursinus.edu/grizzlynews/1006/thumbnail.jp

The Grizzly, February 2, 1979

Frat Beating Draws Administrative Fire • New Frat Gathers Steam • Holiday Thefts: Negligence or Lack of Concern? • In Memoriam • Judiciary Board Revival • Cultural Kaleidoscope • Letters to the Editor: Snack shop complaint • Roving Reporter: Greaseband opinions • Dishroom Profile: Roy Schuetz, Man or Myth? • Grease Is The Word • Nicolette Larson Debuts In Style • USGA Elections • Portrait of the Professor: Dr. Conrad E. Kruse • Raquetball Review • Bio Club Spawned • R.A. Applications Available; Ruby Seeks Editor • Gymnasts Place Third In Tourney • Bears Turning Corner • Slavin Breaks Record Mermaids Lose • Wrestlers Manhandle Mules • Badminton Drops Onehttps://digitalcommons.ursinus.edu/grizzlynews/1011/thumbnail.jp

The Grizzly, January 26, 1979

Campus Life Committee to Replace SFARC • Quad Fire Brought Quickly Under Control • The Fabulous Greaseband Presents...Rock \u27N\u27 Roll Revue Tonight • Christmas Thefts Hit Women\u27s Dorms • Four-One-Four Proposed • Integrated Dining: An Interesting Proposal • Low Attendance Attracts Attention • Letters to the Editor: No static at all?; Big-name concert • Roving Reporter: Alcohol policy • Ritter Gift • Class Skiing Trips: Coming Up • Billy Joel: Isn\u27t One Elton John Enough? • Grateful Dead Rocks Spectrum • Operatic Forum • Audio Corner: Receivers • Token Tolkien • Financial aid night to be held; Meistersingers on tour; New sports editor; Gift collection received; William J. Phillip prize endowed • USGA Elections Near • Bears Sink Below .500 • Cagers Capture Only One Of Six • Flying Fish • Grapplers Groping • Girl\u27s B-Ballhttps://digitalcommons.ursinus.edu/grizzlynews/1010/thumbnail.jp

An Application of the Concept of the Therapeutic Alliance To Sadomasochistic Pathology

This paper traces the history of the therapeutic alliance concept, examining how it has been used and misused, at times elevated to a central position and at others rejected altogether. The loss of this concept created a vacuum in classical psychoanalysis that has been filled by rival theories. The continuing usefulness of looking at the treatment process through the lens of the therapeutic alliance, particularly in relation to the manifold difficulties of working with sadomasochistic pathology, is suggested. To this end, revisions of the theory of the therapeutic alliance are suggested to address some of the difficulties that have arisen in conceptualizing this aspect of the therapeutic relationship, and to provide an integrated dynamic model for working with patients at each phase of treatment. This revised model acknowledges the complexity of the domain and encompasses the multiple tasks, functions, partners, and treatment phases involved. The utility of the revised theory is illustrated in application to understanding the sadomasochistic, omnipotent resistances of a female patient through the phases of her analysis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66889/2/10.1177_00030651980460031301.pd

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure

Why Are Computational Neuroscience and Systems Biology So Separate?

Despite similar computational approaches, there is surprisingly little interaction between the computational neuroscience and the systems biology research communities. In this review I reconstruct the history of the two disciplines and show that this may explain why they grew up apart. The separation is a pity, as both fields can learn quite a bit from each other. Several examples are given, covering sociological, software technical, and methodological aspects. Systems biology is a better organized community which is very effective at sharing resources, while computational neuroscience has more experience in multiscale modeling and the analysis of information processing by biological systems. Finally, I speculate about how the relationship between the two fields may evolve in the near future

Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner

Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman primates. Previous studies suggest roles for clathrin- or caveolae-mediated endocytosis in EBOV entry; however, ebolavirus virions are long, filamentous particles that are larger than the plasma membrane invaginations that characterize clathrin- or caveolae-mediated endocytosis. The mechanism of EBOV entry remains, therefore, poorly understood. To better understand Ebolavirus entry, we carried out internalization studies with fluorescently labeled, biologically contained Ebolavirus and Ebolavirus-like particles (Ebola VLPs), both of which resemble authentic Ebolavirus in their morphology. We examined the mechanism of Ebolavirus internalization by real-time analysis of these fluorescently labeled Ebolavirus particles and found that their internalization was independent of clathrin- or caveolae-mediated endocytosis, but that they co-localized with sorting nexin (SNX) 5, a marker of macropinocytosis-specific endosomes (macropinosomes). Moreover, the internalization of Ebolavirus virions accelerated the uptake of a macropinocytosis-specific cargo, was associated with plasma membrane ruffling, and was dependent on cellular GTPases and kinases involved in macropinocytosis. A pseudotyped vesicular stomatitis virus possessing the Ebolavirus glycoprotein (GP) also co-localized with SNX5 and its internalization and infectivity were affected by macropinocytosis inhibitors. Taken together, our data suggest that Ebolavirus is internalized into cells by stimulating macropinocytosis in a GP-dependent manner. These findings provide new insights into the lifecycle of Ebolavirus and may aid in the development of therapeutics for Ebolavirus infection