'Xenia', a new pear cultivar from Moldava, first results in the Netherlands

The pear cultivar `Xenia¿ (synonym `Noiabriskaia¿) from Moldova is a selection from a cross between `Triomphe de Vienne¿ and `Nicolai Krier¿. In The Netherlands, `Xenia¿ has been tested since 2001. So far, trees have given early and high yields and required little thinning. Up to now, a very low to moderate susceptibility to scab (Venturia pirinia) and a very low susceptibility to fruit tree canker (Nectria galligena) have been observed. The trees showed a medium vigour and there was a low tendency to biennial bearing. With the relatively young trees, the average fruit size of `Xenia¿ fruits at full crop was 250-300 g. The harvest window was wide. Fruits of `Xenia¿ had a green ground colour at harvest and were moderately bronzed. `Xenia¿ had a spherical pear shape. The fruits had a strong fruit skin. The firmness was higher than that of `Conference¿. The juiciness varied from juicy to very juicy, depending on the maturity stage. `Xenia¿ had a good eating quality: fresh, slightly aromatic with a typical aroma. The storability of the fruits was very good and the shelf life of `Xenia¿ proved to be much better than of `Conference¿. Summarizing, the first results show a good potential for commercial fruit growing

Focusing of Intense Subpicosecond Laser Pulses in Wedge Targets

Two dimensional particle-in-cell simulations characterizing the interaction of ultraintense short pulse lasers in the range 10^{18} \leq I \leq 10^{20} W/cm^{2} with converging target geometries are presented. Seeking to examine intensity amplification in high-power laser systems, where focal spots are typically non-diffraction limited, we describe key dynamical features as the injected laser intensity and convergence angle of the target are systematically varied. We find that laser pulses are focused down to a wavelength with the peak intensity amplified by an order of magnitude beyond its vacuum value, and develop a simple model for how the peak location moves back towards the injection plane over time. This performance is sustained over hundreds of femtoseconds and scales to laser intensities beyond 10^{20} W/cm^{2} at 1 \mu m wavelength.Comment: 5 pages, 6 figures, accepted for publication in Physics of Plasma

The magnetoelectrochemical switch

In the field of spintronics, the archetype solid-state two-terminal device is the spin valve, where the resistance is controlled by the magnetization configuration. We show here how this concept of spin-dependent switch can be extended to magnetic electrodes in solution, by magnetic control of their chemical environment. Appropriate nanoscale design allows a huge enhancement of the magnetic force field experienced by paramagnetic molecular species in solutions, which changes between repulsive and attractive on changing the electrodes' magnetic orientations. Specifically, the field gradient force created within a sub-100-nm-sized nanogap separating two magnetic electrodes can be reversed by changing the orientation of the electrodes' magnetization relative to the current flowing between the electrodes. This can result in a breaking or making of an electric nanocontact, with a change of resistance by a factor of up to 103. The results reveal how an external field can impact chemical equilibrium in the vicinity of nanoscale magnetic circuits

Nanotrench for nano and microparticle electrical interconnects

We present a simple and versatile patterning procedure for the reliable and reproducible fabrication of high aspect ratio (10 4 ) electrical interconnects that have separation distances down to 20 nm and lengths of several hundreds of microns. The process uses standard optical lithography techniques and allows parallel processing of many junctions, making it easily scalable and industrially relevant. We demonstrate the suitability of these nanotrenches as electrical interconnects for addressing micro and nanoparticles by realizing several circuits with integrated species. Furthermore, low impedance metal-metal low contacts are shown to be obtained when trapping a single metal-coated microsphere in the gap, emphasizing the intrinsic good electrical conductivity of the interconnects, even though a wet process is used. Highly resistive magnetite-based nanoparticles networks also demonstrate the advantage of the high aspect ratio of the nanotrenches for providing access to electrical properties of highly resistive materials, with leakage current levels below 1 pA. © 2010 IOP Publishing Ltd

Laboratory and Clinical Studies of Cardiac Transplantation

Cardiac transplantation was carried out on four patients at the Medical College of Virginia between May and October of 1968, in an effort to salvage them from the terminal stages of otherwise uncorrectable heart disease. Despite a strikingly good early recovery from operation in each case, three of the patients died of acute homograft rejection in one to three weeks; our second case is living and well, ten months after operation, and is at this writing the world\u27s third longest survivor. The world experience to June of 1969 includes about 130 cardiac transplants. Of the first 100 patients operated on over six months ago, 20 are surviving, and the majority of these have returned to a productive existence, demonstrating the feasibility of complete rehabilitation of at least some terminal patients after cardiac transplantation. The high mortality rate--significantly higher than was anticipated--has resulted from acute and chronic homograft rejection and from the equally difficult problem of infection. Certain lessons have been learned from our own experience and from the world experience with this procedure, and these will be reviewed in an attempt to establish the current status and future potential of cardiac transplantation

The system parameters of DW Ursae Majoris

We present new constraints on the system parameters of the SW Sextantis star DW Ursae Majoris, based on ultraviolet (UV) eclipse observations with the Hubble Space Telescope. Our data were obtained during a low state of the system, in which the UV light was dominated by the hot white dwarf (WD) primary. Eclipse analysis, using the full Roche lobe geometry, allows us to set firm limits on the masses and radii of the system components and the distance between them: 0.67 \leq M_1/M_sun \leq 1.06, 0.008 \leq R_1/R_sun \leq 0.014, M_2/M_sun > 0.16, R_2/R_sun > 0.28 and a/R_sun > 1.05. For q = M_2/M_1 < 1.5 the inclination must satisfy i > 71 degrees. Using Smith & Dhillon's mass-period relation for CV secondaries, our estimates for the system parameters become M_1/M_sun = 0.77 \pm 0.07, R_1/R_sun = 0.012 \pm 0.001, M_2/M_sun = 0.30 \pm 0.10, R_2/R_sun = 0.34 \pm 0.04, q =0.39 \pm 0.12, i = 82 \pm 4 degrees and a/R_sun = 1.14 \pm 0.06. We have also estimated the spectral type of the secondary, M3.5 \pm 1.0, and distance to the system, d =930 \pm 160 pc, from time-resolved I- and K-band photometry. Finally, we have repeated Knigge et al.'s WD model atmosphere fit to the low-state UV spectrum of DW UMa in order to account for the higher surface gravity indicated by our eclipse analysis. In this way we obtained a second estimate for the distance, d = 590 \pm 100 pc, which allows us to obtain a second estimate for the spectral type of the secondary, M7 \pm 2.0. We conclude that the true value for the distance and spectral type will probably be in between the values obtained by the two methods.Comment: 23 pages including 5 figures and 3 tables. Accepted for publication in Ap

First CNGS events detected by LVD

The CERN Neutrino to Gran Sasso (CNGS) project aims to produce a high energy, wide band $\nu_{\mu}$ beam at CERN and send it toward the INFN Gran Sasso National Laboratory (LNGS), 732 km away. Its main goal is the observation of the $\nu_{\tau}$ appearance, through neutrino flavour oscillation. The beam started its operation in August 2006 for about 12 days: a total amount of $7.6~10^{17}$ protons were delivered to the target. The LVD detector, installed in hall A of the LNGS and mainly dedicated to the study of supernova neutrinos, was fully operating during the whole CNGS running time. A total number of 569 events were detected in coincidence with the beam spill time. This is in good agreement with the expected number of events from Montecarlo simulations.Comment: Accepted for publication by the European Physical Journal C ; 7 pages, 11 figure

On-line recognition of supernova neutrino bursts in the LVD detector

In this paper we show the capabilities of the Large Volume Detector (INFN Gran Sasso National Laboratory) to identify a neutrino burst associated to a supernova explosion, in the absence of an "external trigger", e.g., an optical observation. We describe how the detector trigger and event selection have been optimized for this purpose, and we detail the algorithm used for the on-line burst recognition. The on-line sensitivity of the detector is defined and discussed in terms of supernova distance and electron anti-neutrino intensity at the source.Comment: Accepted for pubblication on Astroparticle Physics. 13 pages, 10 figure

Increased levels of RNA oxidation enhance the reversion frequency in aging pro-apoptotic yeast mutants

Despite recent advances in understanding the complexity of RNA processes, regulation of the metabolism of oxidized cellular RNAs and the mechanisms through which oxidized ribonucleotides affect mRNA translation, and consequently cell viability, are not well characterized. We show here that the level of oxidized RNAs is markedly increased in a yeast decapping Kllsm4Δ1 mutant, which accumulates mRNAs, ages much faster that the wild type strain and undergoes regulated-cell-death. We also found that in Kllsm4Δ1 cells the mutation rate increases during chronological life span indicating that the capacity to han- dle oxidized RNAs in yeast declines with aging. Lowering intracellular ROS levels by antioxidants recovers the wild- type phenotype of mutant cells, including reduced amount of oxidized RNAs and lower mutation rate. Since mRNA oxidation was reported to occur in different neurodegen- erative diseases, decapping-deficient cells may represent a useful tool for deciphering molecular mechanisms of cell response to such conditions, providing new insights into RNA modification-based pathogenesis

Dynamics of Sleep-Wake Transitions During Sleep

We study the dynamics of the awakening during the night for healthy subjects and find that the wake and the sleep periods exhibit completely different behavior: the durations of wake periods are characterized by a scale-free power-law distribution, while the durations of sleep periods have an exponential distribution with a characteristic time scale. We find that the characteristic time scale of sleep periods changes throughout the night. In contrast, there is no measurable variation in the power-law behavior for the durations of wake periods. We develop a stochastic model which agrees with the data and suggests that the difference in the dynamics of sleep and wake states arises from the constraints on the number of microstates in the sleep-wake system.Comment: Final form with some small corrections. To be published in Europhysics Letters, vol. 57, issue no. 5, 1 March 2002, pp. 625-63