116 research outputs found
The GlueX DIRC Project
The GlueX experiment was designed to search for and study the pattern of
gluonic excitations in the meson spectrum produced through photoproduction
reactions at a new tagged photon beam facility in Hall D at Jefferson
Laboratory. The particle identification capabilities of the GlueX experiment
will be enhanced by constructing a DIRC (Detection of Internally Reflected
Cherenkov light) detector, utilizing components of the decommissioned BaBar
DIRC. The DIRC will allow systematic studies of kaon final states that are
essential for inferring the quark flavor content of both hybrid and
conventional mesons. The design for the GlueX DIRC is presented, including the
new expansion volumes that are currently under development.Comment: 8 pages, 6 figure
The Importance of Hands-on Experience with Telescopes for Students
Proper interpretation and understanding of astronomical data requires good
knowledge of the data acquisition process. The increase in remote observing,
queue observing, and the availability of large archived data products risk
insulating astronomers from the telescope, potentially reducing their
familiarity with the observational techniques crucial in understanding the
data. Learning fundamental observing techniques can be done in at least three
ways: 1) College and university operated observing facilities, 2) Student
involvement in national facilities through competitive proposals, 3) Programs
at national facilities to increase upper-level undergraduate and graduate
student exposure to telescopes. We encourage both national organizations and
universities to include programs and funding aimed at supporting hands-on
experience with telescopes through the three methods mentioned.Comment: "State of the Profession" white paper for the 2010 Astronomy and
Astrophysics Decadal Surve
Why Do Developers Get Password Storage Wrong? A Qualitative Usability Study
Passwords are still a mainstay of various security systems, as well as the
cause of many usability issues. For end-users, many of these issues have been
studied extensively, highlighting problems and informing design decisions for
better policies and motivating research into alternatives. However, end-users
are not the only ones who have usability problems with passwords! Developers
who are tasked with writing the code by which passwords are stored must do so
securely. Yet history has shown that this complex task often fails due to human
error with catastrophic results. While an end-user who selects a bad password
can have dire consequences, the consequences of a developer who forgets to hash
and salt a password database can lead to far larger problems. In this paper we
present a first qualitative usability study with 20 computer science students
to discover how developers deal with password storage and to inform research
into aiding developers in the creation of secure password systems
Does Uptake of Pharmaceuticals Vary Across Earthworm Species?
This study compared the uptake and depuration of four commonly used pharmaceuticals (carbamazepine, diclofenac, fluoxetine and orlistat) in two earthworm species (Lumbricus terrestris and Eisenia fetida). L. terrestris are a larger species and often found in deep burrows whereas E. fetida prefer to reside near the soil surface. Species burrowing habits and sizes may alter uptake by earthworms. All four pharmaceuticals were taken up into both L. terrestris and E. fetida tissue after 21 days exposure to spiked soil. Bioconcentration factors (BCFs) ranged between 1.72 and 29.83 for L. terrestris and 1.14 and 63.03 for E. fetida. For carbamazepine and diclofenac, BCFs were similar whereas for fluoxetine and orlistat, BCFs in E. fetida were more than double those seen in L. terrestris. Results indicate that uptake into earthworms cannot be generalised between species and that the influence of species traits can vary depending on the nature of the study chemical
Space Science Opportunities Augmented by Exploration Telepresence
Since the end of the Apollo missions to the lunar surface in December 1972, humanity has exclusively conducted scientific studies on distant planetary surfaces using teleprogrammed robots. Operations and science return for all of these missions are constrained by two issues related to the great distances between terrestrial scientists and their exploration targets: high communication latencies and limited data bandwidth.
Despite the proven successes of in-situ science being conducted using teleprogrammed robotic assets such as Spirit, Opportunity, and Curiosity rovers on the surface of Mars, future planetary field research may substantially overcome latency and bandwidth constraints by employing a variety of alternative strategies that could involve: 1) placing scientists/astronauts directly on planetary surfaces, as was done in the Apollo era; 2) developing fully autonomous robotic systems capable of conducting in-situ field science research; or 3) teleoperation of robotic assets by humans sufficiently proximal to the exploration targets to drastically reduce latencies and significantly increase bandwidth, thereby achieving effective human telepresence.
This third strategy has been the focus of experts in telerobotics, telepresence, planetary science, and human spaceflight during two workshops held from October 3–7, 2016, and July 7–13, 2017, at the Keck Institute for Space Studies (KISS). Based on findings from these workshops, this document describes the conceptual and practical foundations of low-latency telepresence (LLT), opportunities for using derivative approaches for scientific exploration of planetary surfaces, and circumstances under which employing telepresence would be especially productive for planetary science. An important finding of these workshops is the conclusion that there has been limited study of the advantages of planetary science via LLT. A major recommendation from these workshops is that space agencies such as NASA should substantially increase science return with greater investments in this promising strategy for human conduct at distant exploration sites
Space Science Opportunities Augmented by Exploration Telepresence
Since the end of the Apollo missions to the lunar surface in December 1972, humanity has exclusively conducted scientific studies on distant planetary surfaces using teleprogrammed robots. Operations and science return for all of these missions are constrained by two issues related to the great distances between terrestrial scientists and their exploration targets: high communication latencies and limited data bandwidth.
Despite the proven successes of in-situ science being conducted using teleprogrammed robotic assets such as Spirit, Opportunity, and Curiosity rovers on the surface of Mars, future planetary field research may substantially overcome latency and bandwidth constraints by employing a variety of alternative strategies that could involve: 1) placing scientists/astronauts directly on planetary surfaces, as was done in the Apollo era; 2) developing fully autonomous robotic systems capable of conducting in-situ field science research; or 3) teleoperation of robotic assets by humans sufficiently proximal to the exploration targets to drastically reduce latencies and significantly increase bandwidth, thereby achieving effective human telepresence.
This third strategy has been the focus of experts in telerobotics, telepresence, planetary science, and human spaceflight during two workshops held from October 3–7, 2016, and July 7–13, 2017, at the Keck Institute for Space Studies (KISS). Based on findings from these workshops, this document describes the conceptual and practical foundations of low-latency telepresence (LLT), opportunities for using derivative approaches for scientific exploration of planetary surfaces, and circumstances under which employing telepresence would be especially productive for planetary science. An important finding of these workshops is the conclusion that there has been limited study of the advantages of planetary science via LLT. A major recommendation from these workshops is that space agencies such as NASA should substantially increase science return with greater investments in this promising strategy for human conduct at distant exploration sites
Federated Identity Management for Research Collaborations
This white-paper expresses common requirements of Research Communities seeking to leverage Identity Federation for
Authentication and Authorisation. Recommendations are made to Stakeholders to guide the future evolution of Federated
Identity Management in a direction that better satisfies research use cases. The authors represent research communities,
Research Services, Infrastructures, Identity Federations and Interfederations, with a joint motivation to ease collaboration
for distributed researchers. The content has been edited collaboratively by the Federated Identity Management for
Research (FIM4R) Community, with input sought at conferences and meetings in Europe, Asia and North America
Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese
<p>Abstract</p> <p>Background</p> <p>Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the intervertebral disc. A SNP for guanine insertion/deletion (G/D), the -1607 promoter polymorphism, of the <it>MMP1 </it>gene was found significantly affecting promoter activity and corresponding transcription level. Hence it is a good candidate for genetic studies in DDD.</p> <p>Methods</p> <p>Southern Chinese volunteers between 18 and 55 years were recruited from the population. DDD in the lumbar spine was defined by MRI using Schneiderman's classification. Genomic DNA was isolated from the leukocytes and genotyping was performed using the Sequenom<sup>® </sup>platform. Association and Hardy-Weinberg equilibrium checking were assessed by Chi-square test and Mann-Whitney U test.</p> <p>Results</p> <p>Our results showed substantial evidence of association between -1607 promoter polymorphism of <it>MMP1 </it>and DDD in the Southern Chinese subjects. D allelic was significantly associated with DDD (p value = 0.027, odds ratio = 1.41 with 95% CI = 1.04–1.90) while Genotypic association on the presence of D allele was also significantly associated with DDD (p value = 0.046, odds ratio = 1.50 with 95% CI = 1.01–2.24). Further age stratification showed significant genotypic as well as allelic association in the group of over 40 years (genotypic: p value = 0.035, odds ratio = 1.617 with 95% CI = 1.033–2.529; allelic: p value = 0.033, odds ratio = 1.445 with 95% CI = 1.029–2.029). Disc bulge, annular tears and the Schmorl's nodes were not associated with the D allele.</p> <p>Conclusion</p> <p>We demonstrated that individuals with the presence of D allele for the -1607 promoter polymorphism of <it>MMP1 </it>are about 1.5 times more susceptible to develop DDD when compared with those having G allele only. Further association was identified in individuals over 40 years of age. Disc bulge, annular tear as well as Schmorl's nodes were not associated with this polymorphism.</p
An Association Study of Interleukin 18 Receptor Genes (IL18R1 and IL18RAP) in Lumbar Disc Degeneration
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