The Fate of Napster: Digital Downloading Faces an Uphill Battle

First Diamond Multimedia, then MP3.com, now Napster. The recording industry, in a flurry to protect its copyrighted material, has waged an all-out battle against the dot-coms for the future of copyrighted music on the Internet. Since A&M Records, along with several other labels which comprise the Recording Industry Association of America (RIAA), filed suit against Napster, emotions have run high in the online community. Some have heralded this technology as a much-needed alternative to the strangling grasp of the major record labels; others view it as blatant theft of property. Students, musicians, computer programmers, trade organizations, and even the US government have voiced their opinions - all perhaps sensing that the outcome of the Napster litigation will have far-reaching consequences. Not only does the current battle over the fate of peer-to-peer technology promise to reshape the face of copyright law, it will also mark the future of the music industry, emerging technologies, and business models for years to come.The following iBrief describes the emergence of Napster\u27s peer-to-peer technology, the legal proceedings to date, and Napster\u27s defensive strategy, as well as the potential technological and cultural ramifications of the Napster cause celebr

The Fate of Napster: Digital Downloading Faces an Uphill Battle

First Diamond Multimedia, then MP3.com, now Napster. The recording industry, in a flurry to protect its copyrighted material, has waged an all-out battle against the dot-coms for the future of copyrighted music on the Internet. Since A&M Records, along with several other labels which comprise the Recording Industry Association of America (RIAA), filed suit against Napster, emotions have run high in the online community. Some have heralded this technology as a much-needed alternative to the strangling grasp of the major record labels; others view it as blatant theft of property. Students, musicians, computer programmers, trade organizations, and even the US government have voiced their opinions - all perhaps sensing that the outcome of the Napster litigation will have far-reaching consequences. Not only does the current battle over the fate of peer-to-peer technology promise to reshape the face of copyright law, it will also mark the future of the music industry, emerging technologies, and business models for years to come.The following iBrief describes the emergence of Napster\u27s peer-to-peer technology, the legal proceedings to date, and Napster\u27s defensive strategy, as well as the potential technological and cultural ramifications of the Napster cause celebr

The Future of Database Protection in U.S. Copyright Law

In the recent British Horseracing Board case, the English High Court signaled a return to the sweat of the brow standard of copyright protection. Although recent attempts have been made in the United States to protect databases under this standard, this iBrief argues that the information economy is wise to continuing protecting this data through trade secret, State misappropriation and contract law until legislation is passed

Retrospective cohort study of the South Tyneside Exercise Referral scheme 2009-2014: Predictors of dropout and barriers to adherence

Background: Exercise Referral Schemes (ERS) are a prevalent method of increasing physical activity levels. However, they suffer from participant dropout and research predicting dropout or barriers to adherence is limited. This study aimed to focus upon the effect of referral characteristics on dropout, dropout predictors and whether self-reported barriers to exercise predict dropout. Methods: ERS data from 2009-2014 were retrieved for analysis. Chi squared and t-tests were used to investigate differences between referral characteristics, and logistic regression used to investigate dropout predictors. Results: Of 6894 participants, 37.8% (n=2608) dropped out within 6 weeks and 50.03% (n=3449) by the final 12th week. More males adhered (p<0.001) with dropouts being significantly younger (p<0.001). Dropout predictors were smoking (OR=1.58, 95% CI:1.29-1.93) or being a Tier 3 referral (OR=1.47, 95% CI:1.25-1.73). Increasing age (OR=0.98, 95% CI:0.98-0.99), drinking alcohol (OR=0.82, 95% CI:0.71-0.95), secondary care referrals (OR=0.68, 95% CI:0.52-0.90), having a lack of motivation (OR=0.81, 95% CI:0.69-0.95), or a lack of childcare (OR=0.69, 95% CI:0.50-0.95) decreased the likelihood of dropout. Conclusion: ERS dropout continues to be problematic. Smoking and having moderate-high comorbidities predicted dropout. Increasing age and patient-reported barriers of a lack of time or childcare decreased dropout risk. The reasons for dropout require further investigation

Copper mediated polymerization without external deoxygenation or oxygen scavengers

Overcoming the challenge of rigorous deoxygenation in copper mediated controlled radical polymerization processes (e.g. ATRP), we report a simple Cu(0)‐RDRP system in the absence of external additives (e.g. reducing agents, enzymes etc.). By simply adjusting the headspace of the reaction vessel, a wide range of monomers, namely acrylates, methacrylates, acrylamides and styrene, can be polymerized in a controlled manner yielding polymers with low dispersities, near‐quantitative conversions and high end group fidelity. Significantly, this approach is scalable (~ 125 g), tolerant to elevated temperatures, compatible with both organic and aqueous media and does not rely on external stimuli which may limit the monomer pool. The robustness and versatility of this methodology is further demonstrated by the applicability to a number of other copper mediated techniques including conventional ATRP and light‐mediated approaches

The characterization and manipulation of the bacterial microbiome of the Rocky Mountain wood tick, Dermacentor andersoni

BACKGROUND: In North America, ticks are the most economically impactful vectors of human and animal pathogens. The Rocky Mountain wood tick, Dermacentor andersoni (Acari: Ixodidae), transmits Rickettsia rickettsii and Anaplasma marginale to humans and cattle, respectively. In recent years, studies have shown that symbiotic organisms are involved in a number of biochemical and physiological functions. Characterizing the bacterial microbiome of D. andersoni is a pivotal step towards understanding symbiont-host interactions. FINDINGS: In this study, we have shown by high-throughput sequence analysis that the composition of endosymbionts in the midgut and salivary glands in adult ticks is dynamic over three generations. Four Proteobacteria genera, Rickettsia, Francisella, Arsenophonus, and Acinetobacter, were identified as predominant symbionts in these two tissues. Exposure to therapeutic doses of the broad-spectrum antibiotic, oxytetracycline, affected both proportions of predominant genera and significantly reduced reproductive fitness. Additionally, Acinetobacter, a free-living ubiquitous microbe, invaded the bacterial microbiome at different proportions based on antibiotic treatment status suggesting that microbiome composition may have a role in susceptibility to environmental contaminants. CONCLUSIONS: This study characterized the bacterial microbiome in D. andersoni and determined the generational variability within this tick. Furthermore, this study confirmed that microbiome manipulation is associated with tick fitness and may be a potential method for biocontrol

HI Clouds in the M81 Filament as Dark Matter Minihalos--A Phase-Space Mismatch

Cosmological galaxy formation models predict the existence of dark matter minihalos surrounding galaxies and in filaments connecting groups of galaxies. The more massive of these minihalos are predicted to host HI gas that should be detectable by current radio telescopes such as the GBT. We observed the region including the M81/M82 and NGC 2403 galaxy groups, searching for observational evidence of an HI component associated with dark matter halos within the "M81 Filament", using the Robert C. Byrd Green Bank Telescope (GBT). The map covers an 8.7 degree x 21.3 degree (480 kpc x 1.2 Mpc) region centered between the M81/M82 and NGC 2403 galaxy groups. Our observations cover a wide velocity range, from -890 to 1320 km/s, which spans much of the range predicted by cosmological N-body simulations for dark matter minihalo velocities. Our search is not complete in the velocity range -210 to 85 km/s, containing Galactic emission and the HVC Complex A. For an HI cloud at the distance of M81, with a size < 10 kpc, our average 5-sigma mass detection limit is 3.2 x 10^6 M_Sun, for a linewidth of 20 km/s. We compare our observations to two large cosmological N-body simulations and find that the simulation predicts a significantly greater number of detectable minihalos than are found in our observations, and that the simulated minihalos do not match the phase space of observed HI clouds. These results place strong constraints on the HI gas that can be associated with dark-matter halos. Our observations indicate that the majority of extragalactic HI clouds with a mass greater than 10^6 M_Sun are likely to be generated through tidal stripping caused by galaxy interactions.Comment: 15 pages, 7 figures. Accepted for publication in the AJ with minor revision