T2K ECAL Test–beam Proposal

The T2K experiment will search for the last unknown element of the neutrino mixing matrix. An crucial component of the near detector for this experiment is the electromagnetic calorimeter which is being built in the UK. Testbeam time is requested to test the full ECAL system, validate calibration techniques, and determine the hadronic and electromagnetic energy scale of the calorimeter

Dyadic adjustment, family coping, body image, quality of life and psychological morbidity in patients with psoriasis and their partners

Background Psoriasis is an incurable and chronic disease that includes unpredictable periods of remission and relapse requiring long-term therapy. Purpose This paper focuses on the relationship among family coping, psychological morbidity, body image, dyadic adjustment and quality of life in psoriatic patients and their partners. Method One hundred and one patients with psoriasis and 78 partners comprised the sample. They were regular users of the Dermatology Service of a Central Northern hospital in Portugal and a private dermatology clinic. Patients with psoriasis were assessed on anxiety, depression, body image, quality of life, dyadic adjustment and family coping. Partners were assessed on the same measures except body image and quality of life. Results A positive relationship among dyadic adjustment, psychological morbidity and family coping in patients and their partners was found. Also, patients with lower levels of quality of life had partners with higher levels of depressive and anxious symptoms. Better dyadic adjustment predicted family coping in the psoriatic patient. High levels of dyadic adjustment in patients and low partners’ trait anxiety predicted better dyadic adjustment in partners. Conclusion The results highlight the importance of incorporating family variables in psychological interventions in psoriasis’ care, particularly family coping and dyadic adjustment as well as the need for psychological intervention to focus both on patients and partners

2. Pathways to detection of non-infectious childhood uveitis in the UK: findings from the UNICORN cohort study

Introduction Prompt detection of childhood uveitis is key to minimising negative impact. From an internationally unique inception cohort, we report pathways to disease detection. UNICORNS is a national childhood non-infectious uveitis study with longitudinal collection of a standardised clinical dataset and patient reported outcomes. Descriptive analysis of baseline characteristics are reported. Amongst 150 recruited children (51% female, 31% non-white ethnicity) age at detection ranged from 2–18yrs (median 10). In 69%, uveitis was diagnosed following onset of symptoms: time from first symptoms to uveitis detection ranged from 0-739days (median 7days), with longer time to detection for those presenting initially to their general practitioner. Non symptomatic children were detected through JIA/other disease surveillance (16%), routine optometry review (5%) or child visual health screening (1%). Commonest underlying diagnoses at uveitis detection were JIA (17%), TINU (9%, higher than pre-pandemic reported UK disease frequency) and sarcoid (1%). 60% had no known systemic disease at uveitis detection. At disease detection, in at least one eye: 34% had structural complications (associated with greater time to detection – 17 days versus 4 days for uncomplicated presentation). The larger relative proportions of children with non-JIA uveitis reported here increase the importance of improving awareness of childhood uveitis amongst the wider clinical communities. There is scope for improvement of pathways to detection. Forthcoming analysis on the full cohort (251 recruited to date across 33 hospitals and 4 nations) will provide nationally representative data on management and the determinants of visual and broader developmental/well-being outcomes

Autistic Development, Trauma and Personhood: Beyond the Frame of the Neoliberal Individual

This chapter critically explores notions of childhood development, particularly in regard to autism, reactions to traumatic events and the meaning of ‘personhood’. The construction of the neoliberal individual is contrasted with that of personhood as experienced by an autistic person. Person-centred methods of engagement as outlined in this chapter can give opportunities for opening up a respectful discursive space where autistic development is not framed from the outset as ‘disordered’

The electromagnetic calorimeter for the T2K near detector ND280

The T2K experiment studies oscillations of an off-axis muon neutrino beam between the J-PARC accelerator complex and the Super-Kamiokande detector. Special emphasis is placed on measuring the mixing angle θ 13 by observing ν e appearance via the sub-dominant νμ ν e oscillation and searching for CP violation in the lepton sector. The experiment includes a sophisticated, off-axis, near detector, the ND280, situated 280 m downstream of the neutrino production target in order to measure the properties of the neutrino beam and to understand better neutrino interactions at the energy scale below a few GeV. The data collected with the ND280 are used to study charged- and neutral-current neutrino interaction rates and kinematics prior to oscillation, in order to reduce uncertainties in the oscillation measurements by the far detector. A key element of the near detector is the ND280 electromagnetic calorimeter (ECal), consisting of active scintillator bars sandwiched between lead sheets and read out with multi-pixel photon counters (MPPCs). The ECal is vital to the reconstruction of neutral particles, and the identification of charged particle species. The ECal surrounds the Pi-0 detector (PØD) and the tracking region of the ND280, and is enclosed in the former UA1/NOMAD dipole magnet. This paper describes the design, construction and assembly of the ECal, as well as the materials from which it is composed. The electronic and data acquisition (DAQ) systems are discussed, and performance of the ECal modules, as deduced from measurements with particle beams, cosmic rays, the calibration system, and T2K data, is described.© 2013 IOP Publishing Ltd and Sissa Medialab srl.The ECal detector has been built and is operated using funds provided by the Science and Technology Facilities Council U.K. Important support was also provided by the collaborating institutions. Individual researchers have been supported by the Royal Society and the European Research Council