2,071 research outputs found
Entrepreneurship through acquisition: a study on self-funded search funds
This paper is the first and so far only study on self-funded search funds which is an emerging alternative to the traditional search fund model. The study collects and evaluates primary qualitative data from first-time self-funded searchers. Based on the survey results, self-funded search funds have a shorter search phase, acquire smaller companies by using more debt, and achieve a higher return on invested capital (ROI) and internal rate of return (IRR)than traditional search funds. The evidence presented suggests that searchers decide for a self-funded search because of favorable deal terms at acquisition, more decision-making power and flexibility in acquiring and operating the target company
Hybrid waveguide-bulk multi-path interferometer with switchable amplitude and phase
We design and realise a hybrid interferometer consisting of three paths based
on integrated as well as on bulk optical components. This hybrid construction
offers a good compromise between stability and footprint on one side and means
of intervention on the other. As experimentally verified by the absence of
higher-order interferences, amplitude and phase can be manipulated in all paths
independently. In conjunction with single photons, the setup can, therefore, be
applied for fundamental investigations on quantum mechanics.Comment: accepted in APL Photonic
Healthy Worker Survivor Bias in a Cohort of Uranium Miners from the Colorado Plateau
Radon, a ubiquitous gas present in breathing air and concentrated in the indoor environment, is a well established risk factor for lung cancer. Primarily, evidence for this association originated in studies of miners occupationally exposed to high con- centrations of radon. Much work has been done to predict lung cancer risk due to lower dose exposures in residences using dose-response curves derived from long- term, high-dose miner studies and shorter-term, low-dose residential studies. While residential studies suffer from a high probability of exposure misclassification at low exposures, miner studies present an opportunity to apply more precise estimates of the lung cancer-radon association to risk assessments. However, potential bias due to the Healthy Worker survivor bias has not been addressed in previous studies of occupa- tional exposure to radon. The Healthy Worker survivor bias occurs when workers with poor prognosis leave work sooner than those with better prognosis, thus creating an apparent association between low cumulative occupational exposures and mortality. Healthy worker survivor bias has been shown to substantially bias dose-response esti- mates in other settings, but it has not been explored in occupational studies of radon exposure. We apply two g-methods designed for addressing healthy worker survivor bias that cannot be controlled using conventional statistical methods. We utilize data from the Colorado Plateau uranium miners cohort, which comprises 4,137 male ura- nium miners who agreed to participate in a health study between 1950 and 1960 and were followed up for mortality through 2005. Our results suggest that there may be healthy worker survivor bias of the association between cumulative radon exposure and both lung cancer and all cause mortality. This work highlights the need for non- standard approaches to controlling time-varying confounding in occupational data. We show that, under certain conditions, g-methods can control this confounding, but that careful consideration should be made in the choice of method.Doctor of Philosoph
Neural Microfacet Fields for Inverse Rendering
We present Neural Microfacet Fields, a method for recovering materials,
geometry, and environment illumination from images of a scene. Our method uses
a microfacet reflectance model within a volumetric setting by treating each
sample along the ray as a (potentially non-opaque) surface. Using surface-based
Monte Carlo rendering in a volumetric setting enables our method to perform
inverse rendering efficiently by combining decades of research in surface-based
light transport with recent advances in volume rendering for view synthesis.
Our approach outperforms prior work in inverse rendering, capturing high
fidelity geometry and high frequency illumination details; its novel view
synthesis results are on par with state-of-the-art methods that do not recover
illumination or materials.Comment: Project page: https://half-potato.gitlab.io/posts/nmf
Geometric potential and transport in photonic topological crystals
We report on the experimental realization of an optical analogue of a quantum
geometric potential for light wave packets constrained on thin dielectric
guiding layers fabricated in silica by the femtosecond laser writing
technology. We further demonstrate the optical version of a topological
crystal, with the observation of Bloch oscillations and Zener tunneling of
purely geometric nature
Inhalation Exposures to Particulate Matter and Carbon Monoxide during Ethiopian Coffee Ceremonies in Addis Ababa: A Pilot Study
The unique Ethiopian cultural tradition of the coffee ceremony increases inhalation exposures to combustion byproducts. This pilot study evaluated exposures to particulate matter and carbon monoxide in ten Addis Ababa homes during coffee ceremonies. For coffee preparers the geometric mean (57 μg/m3) and median (72 μg/m3) contributions to an increase in a 24-hour time-weighted average exposure were above World Health Organization (WHO) guidelines. At 40% of the study sites the contribution to the 24-hour average exposure was greater than twice the WHO guideline. Similar exposure increases existed for ceremony participants. Particulate matter concentrations may be related to the use of incense during the ceremony. In nearly all homes the WHO guideline for a 60-minute exposure to carbon monoxide was exceeded. Finding control measures to reduce these exposures will be challenging due to the deeply engrained nature of this cultural practice and the lack of availability of alternative fuels
Identifying and estimating effects of sustained interventions under parallel trends assumptions
Many research questions in public health and medicine concern sustained
interventions in populations defined by substantive priorities. Existing
methods to answer such questions typically require a measured covariate set
sufficient to control confounding, which can be questionable in observational
studies. Differences-in-differences relies instead on the parallel trends
assumption, allowing for some types of time-invariant unmeasured confounding.
However, most existing difference-in-differences implementations are limited to
point treatments in restricted subpopulations. We derive identification results
for population effects of sustained treatments under parallel trends
assumptions. In particular, in settings where all individuals begin follow-up
with exposure status consistent with the treatment plan of interest but may
deviate at later times, a version of Robins' g-formula identifies the
intervention-specific mean under SUTVA, positivity, and parallel trends. We
develop consistent asymptotically normal estimators based on
inverse-probability weighting, outcome regression, and a double robust
estimator based on targeted maximum likelihood. Simulation studies confirm
theoretical results and support the use of the proposed estimators at realistic
sample sizes. As an example, the methods are used to estimate the effect of a
hypothetical federal stay-at-home order on all-cause mortality during the
COVID-19 pandemic in spring 2020 in the United States.Comment: 15 pages, 2 figure
Self-Calibration of Neutrino Detectors using characteristic Backgrounds
We introduce the possibility to use characteristic natural neutrino
backgrounds, such as Geoneutrinos (\bar{\nu}_e) or solar neutrinos (\nu_e),
with known spectral shape for the energy calibration of future neutrino
detectors, e.g. Large Liquid Scintillator Detectors. This "CalEffect" could be
used without the need to apply any modifications to the experiment in all
situations where one has a suitable background with sufficient statistics.
After deriving the effect analytically using \chi^2 statistics, we show that it
is only tiny for reactor neutrino experiments, but can be applicable in other
situations. As an example, we present its impact on the identification of the
wiggles in the power spectrum of supernova neutrinos caused by Earth matter
effects. The Self-Calibration Effect could be used for cross checking other
calibration methods and to resolve systematical effects in the primary neutrino
interaction processes, in particular in the low energy cross sections.Comment: 6 pages, 4 figure
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