Radiometric Model and Inter-Comparison Results of the SGLI-VNR On-Board Calibration

The Second Generation Global Imager (SGLI) on Global Change Observation Mission Climate (GCOM-C) satellite empowers surface and atmospheric measurements related to the carbon cycle and radiation budget, with two radiometers of Visible and Near Infrared Radiometer (SGLI-VNR) and Infrared Scanning Radiometer (SGLI-IRS) that perform a wide-band (380 nm12 m) optical observation not only with as wide as a 11501400 km field of view (FOV), but also with as high as 0.250.5 km resolution. Additionally, polarization and along-track slant view observations are quite characteristic of SGLI. It is important to calibrate radiometers to provide the sensor data records for more than 28 standard products and 23 research products including clouds, aerosols, ocean color, vegetation, snow and ice, and other applications. In this paper, the radiometric model and the first results of on-board calibrations on the SGLI-VNR, which include weekly solar and light-emitting diode (LED) calibration and monthly lunar calibration, will be described. Each calibration data was obtained with corrections, where beta angle correction and avoidance of reflection from multilayer insulation (MLI) were applied for solar calibration; LED temperature correction was performed for LED calibration; and the GIRO (GSICS (Global Space-based Inter-Calibration System) Implementation of the ROLO (RObotic Lunar Observatory) model) model was used for lunar calibration. Results show that the inter-comparison of the relative degradation amount between these three calibrations agreed to within 1% or less

A theoretical approach to thermal noise caused by an inhomogeneously distributed loss -- Physical insight by the advanced modal expansion

We modified the modal expansion, which is the traditional method used to calculate thermal noise. This advanced modal expansion provides physical insight about the discrepancy between the actual thermal noise caused by inhomogeneously distributed loss and the traditional modal expansion. This discrepancy comes from correlations between the thermal fluctuations of the resonant modes. The thermal noise spectra estimated by the advanced modal expansion are consistent with the results of measurements of thermal fluctuations caused by inhomogeneous losses.Comment: 10 pages, 4 figure

Systematic measurement of the intrinsic losses in various kinds of bulk fused silica

We systematically measured and compared the mechanical losses of various kinds of bulk fused silica. Their quality factors ranged widely from 7x10^5 to 4x10^7, the latter being one of the highest reported among bulk fused silica. We observed frequency-dependent losses and a decrease in the losses upon annealing.Comment: 14 pages, 4 figures, Submitted to Phys. Lett.

The Rax homeoprotein in Müller glial cells is required for homeostasis maintenance of the postnatal mouse retina

Müller glial cells, which are the most predominant glial subtype in the retina, play multiple important roles, including the maintenance of structural integrity, homeostasis, and physiological functions of the retina. We have previously found that the Rax homeoprotein is expressed in postnatal and mature Müller glial cells in the mouse retina. However, the function of Rax in postnatal and mature Müller glial cells remains to be elucidated. In the current study, we first investigated Rax function in retinal development using retroviral lineage analysis and found that Rax controls the specification of late-born retinal cell types, including Müller glial cells in the postnatal retina. We next generated Rax tamoxifen–induced conditional KO (Rax iCKO) mice, where Rax can be depleted in mTFP-labeled Müller glial cells upon tamoxifen treatment, by crossing Raxflox/flox mice with Rlbp1-CreERT2 mice, which we have produced. Immunohistochemical analysis showed a characteristic of reactive gliosis and enhanced gliosis of Müller glial cells in Rax iCKO retinas under normal and stress conditions, respectively. We performed RNA-seq analysis on mTFP-positive cells purified from the Rax iCKO retina and found significantly reduced expression of suppressor of cytokine signaling-3 (Socs3). Reporter gene assays showed that Rax directly transactivates the Socs3 promoter. We observed decreased expression of Socs3 in Müller glial cells of Rax iCKO retinas by immunostaining. Taken together, the present results suggest that Rax suppresses inflammation in Müller glial cells by transactivating Socs3. This study sheds light on the transcriptional regulatory mechanisms underlying retinal Müller glial cell homeostasis.Yoshimoto T., Chaya T., Varner L.R., et al. The Rax homeoprotein in Müller glial cells is required for homeostasis maintenance of the postnatal mouse retina. Journal of Biological Chemistry 299, 105461 (2023); https://doi.org/10.1016/j.jbc.2023.105461

Psychosocial twin cohort studies in Japan: the Keio Twin Research Center (KoTReC)

The Keio Twin Research Center (KoTReC) was established in 2009 at Keio University to combine two longitudinal cohort projects — the Keio Twin Study (KTS) for adolescence and adulthood and the Tokyo Twin Cohort Project (ToTCoP) for infancy and childhood. KoTReC also conducted a two-time panel study of self-control and psychopathology in twin adolescence in 2012 and 2013 and three independent anonymous cross-sectional twin surveys (ToTcross) before 2012 — the ToTCross, the Junior and Senior High School Survey and the High School Survey. This article introduces the recent research designs of KoTReC and its publications