Deep redshift topological lensing: strategies for the T^3 candidate

The 3-torus (T^3) FLRW model better fits the nearly zero large-scale auto-correlation of the WMAP CMB sky maps than the infinite flat model. The T^3 model's WMAP parameters imply approximately equal-redshift topological lensing at z \sim 6. We investigate observational strategies for rejecting the T^3 solution or providing candidate topologically lensed galaxy pairs. T^3 holonomies are applied to (i) existing z \sim 6 observations and (ii) simulated observations, creating multiply connected catalogues. Corresponding simply connected catalogues are generated. Each catalogue is analysed using a successive filter method and collecting matched quadruples. Quadruple statistics between the multiply and simply connected catalogues are compared. The expected rejection of the hypothesis, or detection of candidate topologically lensed galaxies, is possible at a significance of 5% for a pair of T^3 axis-centred northern and southern surveys if photometric redshift accuracy is \sigma(\zphot) < 0.01 for a pair of nearly complete 100 deg^2 surveys with a total of > 500 galaxies over 4.3 < z < 6.6, or for a pair of 196 deg^2 surveys with > 400 galaxies and \sigma(\zphot) < 0.02 over 4<z<7. Dropping the maximum time interval in a pair from \Delta t =1 Gyr/h to \Delta t =0.1 Gyr/h yields a requirement of \sigma(\zphot) < 0.005 or \sigma(\zphot) < 0.01, respectively. Millions of z \sim 6 galaxies will be observed over fields of these sizes during the coming decades, implying much stronger constraints. The question is not if the hypothesis will be rejected or confirmed, it is when.Comment: 13 pages, 9 figures, 5 tables, MNRAS, accepte

Nanomaterials to aid wound healing and infection control

The management and treatment of infectious bacterial diseases in wound healing have both become significant research areas in the biomedical field. While current treatments show limitations related to toxicity and exposure time, nanotechnology has become a potential alternative to overcome such challenges. The application of different nanomaterials, with a wide range of elemental compositions, morphologies, and features, has become an essential tool in managing wound healing infections. This book chapter shows an updated view of the newest trends in the control and treatment of bacterial proliferation in the wound bed by utilizing various metal- and nonmetal-based nanostructures

Unmet psychosocial needs in haematological cancer: A systematic review

The final publication is available at Springer via http://dx.doi.org/10.1007/s00520-014-2123-5A systematic review of key online databases and psycho-oncology journals was conducted to identify papers that formally assessed unmet psychosocial needs in adults with a diagnosis of haematological cancer

ATPase activity in macula densa cells of the rabbit kidney

Na-K- and Mg-activated ATPase activities were determined in maculae densae and glomeruli dissected from both superficial and juxtamedullary nephrons of normal rabbits, using an ultramicro method including a cycling reaction. Activities were expressed as P i generated per macula densa or per glomerulus and normalized for tissue volume. Results indicate that the mean volume of superficial and juxtamedullary macula densa samples was not statistically different, while glomeruli from deep nephrons had sample volumes that were 29% larger than those from superficial nephrons ( P <0.001). Correcting for volume both superficial and juxtamedullary macula densa samples had an Na-K-ATPase activity of 0.37±0.21 fmol · h −1 · (μm 3 ) −1 . Mg-ATPase activity in both pools was also similar [0.41±0.07 and 0.52±0.1 fmol · h −1 · (μm 3 ) −1 ]. Na-K-ATPase activity in macula densa cells is estimated to be about 1/40th the activity of surrounding cortical thick ascending limb cells. Total glomerular ATPase per unit volume was significantly higher in glomeruli from superficial than from deep nephrons [0.41±0.04 vs. 0.28±0.04 fmol · h −1 · (μm 3 ) −1 P <0.05]. There was no statistically significant activity of Na-K-ATPase in either superficial or deep glomeruli. These results suggest that in contrast to previous reports, the macula densa contains Na-K-ATPase, but at a low level relative to surrounding tubular cells. Further, in normal rabbits, this activity is invariant in superficial and juxtamedullary samples.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47454/1/424_2004_Article_BF00580725.pd

Antibiotic resistance determinants in the interplay between food and gut microbiota

A complex and heterogeneous microflora performs sugar and lactic acid fermentations in food products. Depending on the fermentable food matrix (dairy, meat, vegetable etc.) as well as on the species composition of the microbiota, specific combinations of molecules are produced that confer unique flavor, texture, and taste to each product. Bacterial populations within such “fermented food microbiota” are often of environmental origin, they persist alive in foods ready for consumption, eventually reaching the gastro-intestinal tract where they can interact with the resident gut microbiota of the host. Although this interaction is mostly of transient nature, it can greatly contribute to human health, as several species within the food microbiota also display probiotic properties. Such an interplay between food and gut microbiota underlines the importance of the microbiological quality of fermented foods, as the crowded environment of the gut is also an ideal site for genetic exchanges among bacteria. Selection and spreading of antibiotic resistance genes in foodborne bacteria has gained increasing interest in the past decade, especially in light of the potential transferability of antibiotic resistance determinants to opportunistic pathogens, natural inhabitants of the human gut but capable of acquiring virulence in immunocompromised individuals. This review aims at describing major findings and future prospects in the field, especially after the use of antibiotics as growth promoters was totally banned in Europe, with special emphasis on the application of genomic technologies to improve quality and safety of fermented foods

Automatic Programming System with Access in The Natural Language

In this paper, acquisition of knowledge from user's programs written in Pascal to the knowledge base of the computer is introduced. It is shown that system with such a kind of knowledge can be used as the automatic programming system. First, representation of knowledge acquired by the computer from different programs is characterized. Then searching for pieces of knowledge in the knowledge base needed for synthesis of a program specified in user requirement is described. Finally, the construction of a new program from the found pieces of knowledge is shown