The anesthetic effects of clove oil and 2-phenoxyethanol on rainbow trout (Oncorhynchus mykiss) at different concentrations and temperatures

In this study, anesthetic effects of five different concentrations of 2-phenoxyethanol (0.2, 0.3, 0.4, 0.5 and 0.6 ml/L) and clove oil (0.50, 0.75, 1.00, 1.25 and 1.50 ml/L) on rainbow trout (Oncorhynchus mykiss) were studied at temperatures 7, 13 and 18ºC. For this purpose, 900 fish (39.08 ± 1.13 g and 15.48 ± 0.21 cm) were used in the experiment. Induction time of 2-phenoxyethanol and clove oil varied between 1.05 and 3.36 min at all concentrations, except for 0.2 ml/L (for 2-phenoxyethanol only) and at every temperature application. Full recovery time occurred between 2.44 and 7.14 min for 2-phenoxyethanol and 3.23 - 6.11 min for clove oil. It was found that full recovery times significantly increased with increase in 2-phenoxyethanol concentrations (r^2=0.81). The same increasing trend was observed in clove oil, but the increase was not strong compared to 2-phenoxyethanol (r^2=0.21). On the other hand, full induction times of 2-phenoxyethanol and clove oil significantly declined with the increase in concentrations (r^2=0.74; r^2=0.84 for 2-phenoxyethanol and clove oil, respectively). Based on the ideal induction (less than 3 min) and recovery (less than 5 min) time criteria, it can be suggested that the most appropriate concentrations for rainbow trout were 0.3, 0.4 and 0.5 ml/L for 2-phenoxyethanol and 0.50, 0.75 and 1.00 ml/L for clove oil

Monocyte/high-density lipoprotein ratio predicts the mortality in ischemic stroke patients

Objective The inflammatory process is a very important stage in the development and prognosis of acute ischemic stroke (AIS). The monocyte to high-density lipoprotein (HDL) ratio (MHR) is accepted as a novel marker for demonstrating inflammation. However, the role of MHR as a predictor of mortality in patients with AIS remains unclear. Methods We retrospectively enrolled 466 patients who were referred to our clinic within the first 24hours of symptom presentation and who were diagnosed with AIS between January 2008 and June 2016. Four hundred and eight controls of similar age and gender were also included. The patient group was classified into two groups according to 30-day mortality. The groups were compared in terms of monocyte counts, HDL, and MHR values. Results The patient group had significantly higher monocyte counts and lower HDL levels; therefore, this group had higher values of MHR compared to controls. Additionally, the monocyte count and MHR value were higher, and the HDL level was lower in non-surviving patients (p<0.001). The MHR value was also observed as a significant independent variable of 30-day mortality in patients with AIS (p<0.001). The optimum cut-off value of MHR in predicting the 30-day mortality for patients with AIS was 17.52 (95% CI 0.95–0.98). Conclusion Our study demonstrated that a high MHR value is an independent predictor of 30-day mortality in patients with AIS

Dystrophic Intracranial Calcification Accompanying Varix of the Dural Sinus and Arteriovenous Malformation

WOS: 00044593940001

ASSOCIATION OF SLEEP QUALITY AND DAYTIME SLEEPINESS WITH COGNITION IN THE ELDERLY

Turkey. The aim of the study was to evaluate the association between sleep quality and daytime sleepiness with cognitive functioning and to identify factors that influence cognitive state in the elderly