A new bounding mechanism for the CNC machine scheduling problems with controllable processing times

Cataloged from PDF version of article.In this study, we determine the upper and lower bounds for the processing time of each job under controllable machining conditions. The proposed bounding scheme is used to find a set of discrete efficient points on the efficient frontier for a bi-criteria scheduling problem on a single CNC machine. We have two objectives; minimizing the manufacturing cost (comprised of machining and tooling costs) and minimizing makespan. The technological restrictions of the CNC machine along with the job specific parameters affect the machining conditions; such as cutting speed and feed rate, which in turn specify the processing times and tool lives. Since it is well known that scheduling problems are extremely sensitive to processing time data, system resources can be utilized much more efficiently by selecting processing times appropriately. 2004 Elsevier B.V. All rights reserved

Scheduling with tool changes to minimize total completion time under controllable machining conditions

Cataloged from PDF version of article.Scheduling under controllable machining conditions has been studied for some time. Scheduling with tool changes, particularly due to tool wear, has just begun to receive attention. Though machining conditions impact tool wear and induce tool change, the two issues have not been considered together.We address for the first time the problem of scheduling a computer numerically controlled (CNC) machine subject to tool changes and controllable machining conditions; our objective is to minimize the total completion time of a given set of jobs. We establish an important result that helps us identify feasible settings of machining parameters such as feed rate and cutting speed. However, the problem at hand remains intractable, even when a single setting is used. In the general case, we are able to solve the problem exactly for up to 30 jobs using a mixed integer linear programming formulation. For larger problems, we turn to approximate solution via heuristics. We examine a number of different schemes. The best of these schemes are used in a problem space genetic algorithm; this produces quality solutions in a time-efficient manner, as is evidenced from an extensive computational study conducted by us. 2005 Elsevier Ltd. All rights reserved

Evaluating Teaching Strategies in Higher Education From Students\u27 Perspectives

This study was conducted to investigate students\u27 perception of learning experiences at one of the largest government universities in the eastern province of Saudi Arabia. The sample consisted of male and female students and their instructors enrolled in four main colleges (Arts, Education, Preparatory year, and Science). Data were collected through a survey and focus group interviews during the fall semester of 2014-2015 academic year. The results provide feedback to faculty members about the quality of content, format, and structure of their courses, and can contribute to teaching and learning processes by facilitating faculty growth, development, and self-improvement

PENINGKATAN HASIL BELAJAR SISWA DALAM MATA PELAJARAN SEJARAH MELALUI PENERAPAN MODEL PEMBELAJARAN GENIUS LEARNING PADA SISWA KELAS XI IPA 1 SMA NEGERI RAMBIPUJI SEMESTER GENAP TAHUN AJARAN 2010/2011

Abstract: the purpose of this study is to know how the application of genius learning is improving student achievements. The research method is a classroom action research. The result  shows than the genius learning can improve the student achievements. Key Words : Genius Learning, Students Achievemen

KAJIAN HISTORIS TENTANG CANDI BADUT DI KABUPATEN MALANG

Abstract : The purpose of this study was to identify the historical temple in Malang Regency clown as a place of Reshi Agastya pendarmaan which was built by the Licwa / Gajayana who ruled the kingdom Gajayana langgam Central Java but geographically located in East Java. The results of this study indicate that there is a motive of political upheaval in Central Java which makes a style temple Clown no influence of style temple in Central Java.   Key Words : Temple clowns, poor districts, style templ

Considering embodied energy and carbon in heritage buildings – a review

Approximately 20% of UK buildings can be defined as ‘heritage buildings’, offering unique values that should be preserved. They tend to use more energy than newer buildings, creating a strong case for energy retrofits to reduce energy use, greenhouse gas emissions, and improve thermal comfort. However, few studies of heritage retrofits examine embodied impacts, which are the energy and carbon impacts required to manufacture, transport and construct materials and components. This study considers the whole life (embodied plus operational) impacts of retrofitting heritage buildings, through a systematic literature review and thematic analysis. It concludes that; both embodied and operational impacts should be considered in retrofitting projects, retrofitting is better than demolish and rebuild in lifecycle terms, there is a lack of policy mandating for the measurement of lifecycle impacts and low impact retrofitting can be better for conserving heritage values and reducing embodied carbon

Elaia, Pergamon's maritime satellite:The rise and fall of an ancient harbour city shaped by shoreline migration

Throughout human history, communication and trade have been key to society. Because maritime trade facilitated the rapid transportation of passengers and freight at relatively low cost, harbours became hubs for traffic, trade and exchange. This general statement holds true for the Pergamenian kingdom, which ruled wide parts of today's western Turkey during Hellenistic times. Its harbour, located at the city of Elaia on the eastern Aegean shore, was used extensively for commercial and military purposes. This study reconstructs the coastal evolution in and around the ancient harbour of Elaia and compares the observed environmental modifications with archaeological and historical findings. We use micropalaeontological, sedimentological and geochemical proxies to reconstruct the palaeoenvironmental dynamics and evolution of the ancient harbour. The geoarchaeological results confirm the archaeological and historical evidence for Elaia's primacy during Hellenistic and early Roman times, and the city's gradual decline during the late Roman period. Furthermore, our study demonstrates that Elaia holds a unique position as a harbour city during ancient times in the eastern Aegean region, because it was not greatly influenced by the high sediment supply associated with river deltas. Consequently, no dredging of the harbour basins is documented, creating exceptional geo-bioarchives for palaeoenvironmental reconstructions

Age-related changes in relative expression stability of commonly used housekeeping genes in selected porcine tissues

<p>Abstract</p> <p>Background</p> <p>Gene expression analysis using real-time RT-PCR (qRT-PCR) is increasingly important in biological research due to the high-throughput and accuracy of qRT-PCR. For accurate and reliable gene expression analysis, normalization of gene expression data against housekeeping genes or internal control genes is required. The stability of reference genes has a tremendous effect on the results of relative quantification of gene expression by qRT-PCR. The expression stability of reference genes could vary according to tissues, age of individuals and experimental conditions. In the pig however, very little information is available on the expression stability of reference genes. The aim of this research was therefore to develop a new set of reference genes which can be used for normalization of mRNA expression data of genes expressed in varieties of porcine tissues at different ages.</p> <p>Results</p> <p>The mRNA expression stability of nine commonly used reference genes (<it>B2M, BLM, GAPDH, HPRT1, PPIA, RPL4, SDHA, TBP </it>and <it>YWHAZ</it>) was determined in varieties of tissues collected from newborn, young and adult pigs. geNorm, NormFinder and BestKeeper software were used to rank the genes according to their stability. geNorm software revealed that <it>RPL4, PPIA </it>and <it>YWHAZ </it>showed high stability in newborn and adult pigs, while <it>B2M, YWHAZ </it>and <it>SDHA </it>showed high stability in young pigs. In all cases, <it>GAPDH </it>showed the least stability in geNorm. NormFinder revealed that <it>TBP </it>was the most stable gene in newborn and young pigs, while <it>PPIA </it>was most stable in adult pigs. Moreover, geNorm software suggested that the geometric mean of three most stable gene would be the suitable combination for accurate normalization of gene expression study.</p> <p>Conclusions</p> <p>Although, there was discrepancy in the ranking order of reference genes obtained by different analysing software methods, the geometric mean of the <it>RPL4, PPIA </it>and <it>YWHAZ </it>seems to be the most appropriate combination of housekeeping genes for accurate normalization of gene expression data in different porcine tissues at different ages.</p

Biochemical and hematologic parameters for children in the middle belt of Ghana.

Reference values derived from developed countries are used in many countries in Africa for interpretation of laboratory results obtained during routine healthcare and clinical trials. Use of locally derived reference values has been recommended. The purpose of the study was to establish age- and sex-specific reference values for children in the middle belt of Ghana. Reference values were determined for 21 biochemical and 18 hematologic parameters by using Clinical and Laboratory Standards Institute C28-A3 guidelines in a sample of 1,442 healthy children. Hemoglobin, hematocrit, mean cell volume, erythrocytes, urea, and creatinine were lower when compared with values from northern countries but alanine aminotransferase, aspartate aminotransferase, and total bilirubin were higher. A panel of locally relevant age- and sex-specific reference values was established for commonly used biochemical and hematologic tests in children in the middle part of Ghana. This will help in interpretation of laboratory results for clinical management of patients, screening, and safety monitoring during clinical trials

Haematological and Biochemical Reference Values for Healthy Adults in the Middle Belt of Ghana

BACKGROUND: Reference values are very important in clinical management of patients, screening participants for enrollment into clinical trials and for monitoring the onset of adverse events during these trials. The aim of this was to establish gender-specific haematological and biochemical reference values for healthy adults in the central part of Ghana. METHODS: A total of 691 adults between 18 and 59 years resident in the Kintampo North Municipality and South District in the central part of Ghana were randomly selected using the Kintampo Health and Demographic Surveillance System and enrolled in this cross-sectional survey. Out of these, 625 adults made up of 316 males and 309 females were assessed by a clinician to be healthy. Median values and nonparametric 95% reference values for 16 haematology and 22 biochemistry parameters were determined for this population based on the Clinical Laboratory and Standards Institute guidelines. Values established in this study were compared with the Caucasian values being used currently by our laboratory as reference values and also with data from other African and western countries. RESULTS: REFERENCE VALUES ESTABLISHED INCLUDE: haemoglobin 113-164 g/L for males and 88-144 g/L for females; total white blood cell count 3.4-9.2 × 10(9)/L; platelet count 88-352 × 10(9)/L for males and 89-403 × 10(9)/L for females; alanine aminotransferase 8-54 U/L for males and 6-51 U/L for females; creatinine 56-119 µmol/L for males and 53-106 µmol/L for females. Using the haematological reference values based on the package inserts would have screened out up to 53% of potential trial participants and up to 25% of the population using the biochemical parameters. CONCLUSION: We have established a panel of locally relevant reference parameters for commonly used haematological and biochemical tests. This is important as it will help in the interpretation of laboratory results both for clinical management of patients and safety monitoring during a trial