Karyological research on Six Different Fennel (Foeniculum vulgare Miller) Population

Bu çalışmada, altı farklı rezene popülasyonu (Foeniculum vulgare Miller) karyolojik özellikleri bakımından araştırılmıştır. Rezene popülasyonlarından dört tanesi Tokat Orta Karadeniz Geçit Kuşağı Tarımsal Araştırma Enstitüsü’nden diğer iki tanesi de Burdur ve Konya illerindeki yerel üreticilerden temin edilmiştir. Bu popülasyonlar; Tokat I, II, III, Urfa, Burdur ve Konya olarak isimlendirilmiştir. Popülasyonların kromozom sayısı, total kromozom uzunluğu, nispi boyu, kol oranı, sentromer indeksi ve sentromer durumları ve karyotip asimetri değerleri belirlenmiştir. Araştırmanın sonuçlarına göre bütün popülasyonlar (2n=2x=22) aynı kromozom sayısına sahiptir. Tokat I, II ve Urfa popülasyonlarının karyotip formülleri aynı 9m+2sm, Tokat III ve Konya popülasyonlarının karyotip formülleri birbiri ile 10m+1sm fakat Burdur popülasyonunun karyotip formülünün 6m+5sm bunlardan farklı olduğu görülmüştür. Bu popülasyonlarda toplam kromozom uzunluğu 30.09- 38.85 μm arasında, sentromerik indeks 27.44- 47.91 μm arasında ve nispi boy 6.52- 11.53 μm arasında değişmektedir.In this study, six different fennel populations (Foeniculum vulgare Miller) were examined in terms of karyological features. Four of the fennel populations were taken from the Tokat Middle Black Sea Transition Zone Agricultural Research Institute, while Burdur and Konya populations were obtained from local producers. These populations; Tokat I, II, III, Urfa, Burdur and Konya are named. Chromosome number, total chromosome length, relative length, arm ratio, centromere index, centromere status and karyotype asymmetry values were determined in these populations. According to the results of the study all populations have the same chromosomes number (2n=2x=22). The karyotype formulas of Tokat I, II and Urfa populations are the same 9m+2sm, the karyotype formulas of Tokat III and Konya populations are the same 10m+1sm, but the karyotype formula of the Burdur population is different 6m+5sm. In these populations the total chromosome length ranged from 30.09 to 38.85 m and the centromeric index ranged from 27.44 to 47.91 μm and the relative size ranged from 6.52 to 11.53 m

The Effects of Superficial Musculoaponeurotic System Flap on the Development of Frey’s Syndrome and Cosmetic Outcomes After Superficial Parotidectomy

Objective:To investigate the outcomes of superficial musculoaponeurotic system (SMAS) flap and classic techniques in superficial parotidectomy in terms of Frey’s syndrome (FS) and cosmetic satisfaction.Methods:In this study, a retrospective chart review of patients that underwent superficial parotidectomy was performed. These patients were divided into two subgroups: group 1 included patients in which the SMAS flap was harvested and group 2 comprised the remaining patients on whom classic superficial parotidectomy was performed. All the patients were evaluated clinically and with Minor’s starch-iodine test for FS. For the evaluation of the cosmetic results, the patient’s satisfaction was queried according to the incision scar and surgical field skin retraction/facial symmetry. Both groups were compared in terms of complications and numbness of surgical area.Results:Fifty-five patients (31 male and 24 female) with a mean age of 50.19 years were included in the study. Thirty-two patients were in group 1 and 23 in group 2. Thirteen patients (23.7%) described as having FS and six of them were in group 1, while seven were in group 2. Minor’s starch-iodine test was positive in nine patients in group 1 (28.1%) and six patients in group 2 (26.1%) (p=1.000). With regard to cosmetic satisfaction, eight patients (25%) stated mild discomfort from the incision scar and two patients (6.3%) stated cosmetic dissatisfaction for facial asymmetry in group 1. In group 2 for the same factors the number of patients were 11 (47.8%) and 2 two (8.7%), respectively (p=0.027). There were no statistically significant differences in means of complication and numbness (p>0.05).Conclusion:According to our study results, there was no superiority between both the groups in terms of FS and incision scar satisfaction. We determined that there was a significant benefit of SMAS flap application in the prevention of volume loss and surgical area retraction

The Experience of Ibrutinib in Chronic Graft-Versus-Host Disease in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: Single Center Experience

Introduction:Chronic graft-versus host disease (GVHD) is a serious complication that develops in 35-50% of patients in the late period after allogeneic hematopoetic stem cell transplantation. About half of the patients are resistant to corticosteroids, which is the first-line treatment of chronic GVHD, and therefore new treatment options that can be effective in chronic GVHD are needed. In the present study, we aimed to share our experience with the use of ibrutinib therapy in patients with steroid-resistant chronic GVHD who have previously received multiple lines of systemic therapy.Methods:The characteristics and clinical outcomes of steroid-resistant chronic patients with GVHD receiving ibrutinib were retrospectively reviewed.Results:A total of 10 steroid resi-stant chronic patients with GVHD who received ibrutinib was included. While 50% of the patients had more than one organ involvement, 50% had a single organ involvement. The most commonly affected organs were the skin and liver. The patients received a median of three lines of systemic therapy before ibrutinib. After a median of 210 days of ibrutinib usage, the complete response rate of patients was 40% and the partial response rate was 40%. Corticosteroids were completely discontinued in 30% of patients after ibrutinib were initiated. Before ibrutinib, patients were given a median of 0.3 mg/kg methylprednisolone. The median methylprednisolone dose after ibrutinib was 0.03 mg/kg.Conclusion:Ibrutinib therapy causes a quite high overall response in steroid resistant chronic patients with GVHD and appears to be a good option in these patients

Triassic gypsum layers in Keban Metamorphics, eastern Tauride Belt, Southeastern Turkey: New data about Triassic rifting in northern Tethys margin

Article; Early AccessA gypsum interlayer with 100 m thick was identified within the Early-Middle Triassic shelf type clastic and carbonates of the Keban Metamorphics, along the shore of the Firat River, similar to 500 m west of Keban district (Elazig, southeast Turkey). Gypsum layers have thickness of 15-50 cm, and exhibit the original sedimentary bedding intercalated with dolomitic carbonate rocks. They were subjected to hydrothermal alteration related to late Cretaceous magmatic intrusions. Hydrothermal activity caused the dissolution and recrystallization of gypsum, as well as occurrences of secondary gypsum, elemental sulphur and quartz (amethyst). The geochemical (trace element and sulphur and oxygen isotope) compositions of gypsum and dolomites indicate typical marine evaporite compositions. The delta S-34 and delta O-18 values of the Keban gypsum correspond to Early Triassic evaporites, based on Early-Middle Triassic seawater sulphate composition. Keban gypsum represents Triassic rifting along the northeastern margin of Gondwana and exhibits similar age (Early-Middle Triassic) and palaeogeographic setting to Kemer (Antalya, Turkey) gypsum, associated with opening of the Neotethyan Ocean between Gondwana (Pangea) and the Cimmerian microcontinent. However, the Keban gypsum is different from the late Triassic Honaz-Denizli and Nusaybin-Gaziantep gypsum representing the southern margin of the Paleo-Tethys Ocean (Tauride Belt) and southern margin of the Neo-Tethys (Arabian Plate). The presence of gypsum is observed on both passive continental margins of Neo-Tethys means that their deposition took place before the subduction of the Neo-Tethys Ocean during Late Triassic-Jurassic period

Effects of Cellulose Micro and Nanocrystals on the Mechanical, Thermal, Morphological, and Structural Properties of Rigid Polyurethanes

Effects of adding microcrystalline cellulose (MCC) and cellulose nanocrystals (CNC) were evaluated relative to the mechanical, thermal, morphological, and structural properties of rigid polyurethanes (rPUs). The composites were prepared with the blending of polyols/isocyanates and the cellulosic fillers at 0.25%, 0.5%, and 1% loadings. Scanning electron microscopic images showed that the samples had micro-scaled porosity, with cell sizes ranging from 250 to 800 nm. The fillers improved the mechanical strengths and modulus of neat rPUs due to the presence of the nano-sized cells in rPUs matrix. The addition of both fillers generally did not provide a positive effect on the thermal properties, and the weight loss generally increased while the loading rate of the fillers was increased from 0.25% to 1%. The samples had two small crystalline peaks at 18° and 19° according to the X-ray diffraction analysis. From the results, it can be said that the presence of both fillers generally improved all properties of the neat rPUs, and the effects of CNC on the properties were higher than MCC due to both lower particle size and the higher crystallinity of CNC

Effects of Cellulose Micro and Nanocrystals on the Mechanical, Thermal, Morphological, and Structural Properties of Rigid Polyurethanes

Effects of adding microcrystalline cellulose (MCC) and cellulose nanocrystals (CNC) were evaluated relative to the mechanical, thermal, morphological, and structural properties of rigid polyurethanes (rPUs). The composites were prepared with the blending of polyols/isocyanates and the cellulosic fillers at 0.25%, 0.5%, and 1% loadings. Scanning electron microscopic images showed that the samples had micro-scaled porosity, with cell sizes ranging from 250 to 800 nm. The fillers improved the mechanical strengths and modulus of neat rPUs due to the presence of the nano-sized cells in rPUs matrix. The addition of both fillers generally did not provide a positive effect on the thermal properties, and the weight loss generally increased while the loading rate of the fillers was increased from 0.25% to 1%. The samples had two small crystalline peaks at 18° and 19° according to the X-ray diffraction analysis. From the results, it can be said that the presence of both fillers generally improved all properties of the neat rPUs, and the effects of CNC on the properties were higher than MCC due to both lower particle size and the higher crystallinity of CNC

Utilisation of antimicrobial agents at pre-and postsmoking on the microbial quality of hot-smoked rainbow trout (oncorhynchus mykiss) fillets

Utilisation of antimicrobial agents at pre-or post-smoking processes was considered for the microbial quality of hot-smoked trout fi llets prepared at plant scale. Potassium sorbate (PS) and sodium lactate (SL) were used separately or in combinations at 3% (w/v) in brine for pre-smoking or with spraying at post-smoking. Pre-smoking usage could reduce the total aerobic mesophilic bacteria (TAMB) values better than the post-smoking usage during storage. However, post-smoking application was more effective at preventing the moulds and yeasts (MY) growth. PS in brine at pre-smoking was most effi cient, which could keep trout fi llets for even four weeks at 6±1°C storage within the range of consumable limits. Additionally, PS usage reduced the contaminated bacterial diversity and especially eliminated the outgrowth of Serratia liquefaciens. As a conclusion, pre-smoking application repressed the contaminated microbial growth during the storage of smoked trout fi llets, which may eliminate the microbial risks. © 2015 Akadémiai Kiadó, Budapest

DİREKT GRAFİDE GÖRÜNMEYEN TEHLİKE; YABANCI CİSİM ASPİRASYON OLGUSU

DİREKT GRAFİDE GÖRÜNMEYEN TEHLİKE; YABANCI CİSİM ASPİRASYON OLGUSUÖmer Can Nazli, Abdil Coşkun, Ali Halıcı, Murtaza Kaya, Harun YıldırımKütahya Sağlık Bilimleri Üniversitesi Acil Tıp Ana Bilim Dalı, KütahyaÖZETYutulmuş yabancı cisimlerin çoğu (yüzde 80 ila 90) müdahaleye gerek kalmadan geçer. Hastaların yüzde 10 ila20'sinde endoskopik müdahale, yüzde 1'den daha azında cerrahi müdahale gereklidir. Tipik klinik sunumdisfajinin akut başlangıcıdır. Özofagus yabancı cisim impaksiyonunun diğer belirtileri arasında boğulma, yemekyemeyi reddetme, hipersalivation, retrosternal dolgunluk bulunur. Odinofaji özofagus spazmına bağlı olabilir,ancak aynı zamanda altta yatan ülserasyon veya perforasyonun göstergesi olabilir. Salya akması ve sıvılarıyutamama, özofagus tıkanıklığının göstergesidir. Bir komplikasyon olmadığında (örneğin, tıkanıklık, perforasyon),yabancı cisim yemek borusunu geçtikten sonra hastaların çoğunluğu asemptomatiktir.30 yaşında erkek hasta yaklaşık 45 dakika önce jilet yutma sonrası kolluk kuvvetleri tarafından acil servise getirildi.Hastanın genel durumu iyi, oryante koopere ve Glaskow Koma Skalası:15 idi. Aktif şikayet tariflemeyen hastanınbatın muayenesi doğal defans, rebound yoktu. Bulantı kusması olmayan hasta genel cerrahi ve gastroenterolojiyekonsülte edildi. Hastaya acil endoskopi planlandı.Yabancı cisimler her zaman direkt grafide görülmeyebileceği gibi akut batın bulguları da vermeyebilir. Bu olgudabilgisayarlı tomografinin önemini vurgulamak istedik.Anahtar kelimeler: yabancı cisim, aspirasyon, bilgisayarlı batın tomografis</p

Two-stage Reimplantation in Infected Total Knee Arthroplasty by Using Resterilized Femoral and Tibial Components with a New Polyethylene Insert: Report of 4 Cases with at Least 15 Years’ Follow-up

Background. This study evaluates 15 years’ results of the implantation of autoclaved femoral and tibial prosthesis components together with a new same brand polyethylene insert which were used as a temporary articulating spacer in patients with periprosthetic infection of total knee arthroplasty (TKA) in a two-stage reimplantation procedure in 6 patients.  Material and methods. The femoral and tibial prostheses of 6 patients with deep chronic periprosthetic infection of TKA who underwent elective two-stage exchange arthroplasty were autoclaved and reinserted with a new polyethylene insert of the same brand and bone cement mixed with tecoplanin in 2004. Results. Four patients were followed for 15 years. They were all female and between 47-70 years old. The infectious agent was meticillin-resistant Staphylococcus aureus (MRSA) in 3 and coagulase negative Staphylococcus in one patient. Patients were invited for second stage reimplantation, but they refused to undergo the second stage. Three of them had their second stage reimplantation after 15, 13 and 10 years while one patient was reinfected after 5 years, in 2009, and arthrodesis was performed. They were all happy with the result and infection free at last follow-up.  Conclusions. 1. Regarding the results of our patients, reinsertion of autoclaved femoral and tibial prostheses together with a new same brand polyethylene insert with teicoplanin loaded bone cement can be used cautiously in the management of periprosthetic deep infection of TKA. 2. That is because patients might not want the second stage reimplantation. 3. We believe that the refusal of patients to undergo the surgery shows that the single-stage treatment is effective