Wear characteristics of bonded solid film lubricant under high load condition

Wear properties of phenolic resin bonded molybdenum disulfide film lubricant were studied. In-vacuo journal bearing tests were performed to evaluate the wear-life of this film lubricant. The wear-life depends on substrate materials and on sliding velocity. Pretreated substrate surfaces were examined to reveal the reasons for these results. Additionally, investigations on film wear mechanisms were made

A Study on the energy consumption of Awaodori-Taisou and Awaodori

阿波踊り体操と阿波踊りのエネルギー消費量を測定することを目的とし，男性13名，女性27名（平均年齢43歳）の被験者に対し，実施中の呼気ガス分析を行った。 阿波踊り体操の平均エネルギー消費は1回（3分半）あたり12kcalで，しっかり強めに実施すると18%増加し，シニア編を座位で行うと8.6kcalであった。 阿波踊りの平均エネルギー消費は1分間あたり5.7kcalで，阿波踊り体操の平均メッツは3.3，しっかり強めに実施すると3.9メッツであった。 エネルギー消費量に影響を与えている要因は，阿波踊り体操の場合は性別と運動習慣であり，阿波踊りでは性別と有名連での経験の有無であった。本研究ではこれらの要因を組み入れたエネルギー消費量の推定式を作成した。Purpose: the aim of this study was to measure an average energy consumption of Awaodori-Taisou and Awaodori. Methods: The participants for this experimentation were composed of 13 males and 27 females, and the average age was 43. The breath was examined during the exercise of Awaodori-Taisou and Awaodori. Result: The average energy consumption of Awaodori-Taisou was 12 kcal/time. When did it briskly, the energy consumption increased by 18%. In the case of senior version with sitting, the average was 8.6 kcal/time. The average of energy consumption of Awaodori was 5.7 kcal per minute. The average mets of Awaodori-Taisou was 3.3. Brisk Awaodori-Taisou was 3.9 mets. Senior version with sitting was 2.3 mets. Awaodori was 5.4 mets. The effect factors influencing energy consumption of Awaodori-Taisou were gender and custom of exercise. The estimate formula of energy consumption was made as follows: Energy consumption (kcal) = weight×0.2×1.1(if male)×1.1(if do exercise more than 3 times a week)×1.1(if do briskly) The effect factors influencing energy consumption of Awaodori were gender and experience of professional group. The estimate formula of energy consumption and mets as follows: Male (professional): 0.13 kcal × time (minutes) × weight: (7.5 mets) Male (none-professional): 0.12 kcal × time (minutes) × weight: (6.5 mets) Female (professional): 0.11 kcal × time (minutes) × weight: (6 mets) Female (none-professional): 0.09 kcal × time (minutes) × weight: (5 mets) Conclusion: The result shows that Awaodori-Taisou and Awaodori have effective intensity for life-style related disease. However, since the quantity of energy consumption of doing Awaodori-Taisou just one time is so little, those who wish to prevent life-style related disease have to do more exercise. Next subject is to measure 'Metabolic Syndrome Prevent Version of Awaodori-Taisou' which was released on November 2008

A Study on the energy consumption of Awaodori-Taisou and Awaodori

阿波踊り体操と阿波踊りのエネルギー消費量を測定することを目的とし，男性13名，女性27名（平均年齢43歳）の被験者に対し，実施中の呼気ガス分析を行った。 阿波踊り体操の平均エネルギー消費は1回（3分半）あたり12kcalで，しっかり強めに実施すると18%増加し，シニア編を座位で行うと8.6kcalであった。 阿波踊りの平均エネルギー消費は1分間あたり5.7kcalで，阿波踊り体操の平均メッツは3.3，しっかり強めに実施すると3.9メッツであった。 エネルギー消費量に影響を与えている要因は，阿波踊り体操の場合は性別と運動習慣であり，阿波踊りでは性別と有名連での経験の有無であった。本研究ではこれらの要因を組み入れたエネルギー消費量の推定式を作成した。Purpose: the aim of this study was to measure an average energy consumption of Awaodori-Taisou and Awaodori. Methods: The participants for this experimentation were composed of 13 males and 27 females, and the average age was 43. The breath was examined during the exercise of Awaodori-Taisou and Awaodori. Result: The average energy consumption of Awaodori-Taisou was 12 kcal/time. When did it briskly, the energy consumption increased by 18%. In the case of senior version with sitting, the average was 8.6 kcal/time. The average of energy consumption of Awaodori was 5.7 kcal per minute. The average mets of Awaodori-Taisou was 3.3. Brisk Awaodori-Taisou was 3.9 mets. Senior version with sitting was 2.3 mets. Awaodori was 5.4 mets. The effect factors influencing energy consumption of Awaodori-Taisou were gender and custom of exercise. The estimate formula of energy consumption was made as follows: Energy consumption (kcal) = weight×0.2×1.1(if male)×1.1(if do exercise more than 3 times a week)×1.1(if do briskly) The effect factors influencing energy consumption of Awaodori were gender and experience of professional group. The estimate formula of energy consumption and mets as follows: Male (professional): 0.13 kcal × time (minutes) × weight: (7.5 mets) Male (none-professional): 0.12 kcal × time (minutes) × weight: (6.5 mets) Female (professional): 0.11 kcal × time (minutes) × weight: (6 mets) Female (none-professional): 0.09 kcal × time (minutes) × weight: (5 mets) Conclusion: The result shows that Awaodori-Taisou and Awaodori have effective intensity for life-style related disease. However, since the quantity of energy consumption of doing Awaodori-Taisou just one time is so little, those who wish to prevent life-style related disease have to do more exercise. Next subject is to measure 'Metabolic Syndrome Prevent Version of Awaodori-Taisou' which was released on November 2008

Identification of three Early Pleistocene tephras in and around the west part of the Musashino Upland, Tokyo, Northeast Japan

In and around the west part of the Musashino Upland, southwest of the Kanto Tectonic Basin, Ob4b-4 (1.62 Ma), Ob4b-1 (1.63 Ma), and Ob3 (1.71-1.78 Ma) tephras in the Kazusa Group, early Quaternary strata, were identified by using characteristic properties such as chemical composition of volcanic glass shards and titanomagnetite, and refractive indices of glass shards, hornblende, cummingtonite, and orthopyroxene. Changes in altitudes of Ob4b-1 identified in four cores and at three outcrops together with those by previous studies indicate geological structure of the Kazusa Group, revealing a gentle northeastward sloping with a gradient of 15/1000 and a prominent discontinuity of the strata along the Tachikawa Fault Zone

Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients

<p>Abstract</p> <p>Background</p> <p>We analyzed the effects of insulin therapy, age and gender on the risk of ischemic heart disease (IHD) and cerebrovascular accident (CVA) according to glycemic control.</p> <p>Methods and Results</p> <p>We performed a prospective cohort study (Japan Cholesterol and Diabetes Mellitus Study) of type 2 diabetes patients (n = 4014) for 2 years. The primary endpoint was the onset of fatal/non-fatal IHD and/or CVA, which occurred at rates of 7.9 and 7.2 per 1000 person-years, respectively. We divided diabetic patients into four groups based on age (≤ 70 and > 70) and hemoglobin A1C levels (≤ 7.0 and > 7.0%). Multiple regression analysis revealed that IHD was associated with high systolic blood pressure and low HDL-C in patients under 70 years of age with fair glycemic control and was associated with low diastolic blood pressure in the older/fair group. Interestingly, insulin use was associated with IHD in the older/poor group (OR = 2.27, 95% CI = 1.11-5.89; p = 0.026) and was associated with CVA in the older/fair group (OR = 2.09, 95% CI = 1.06-4.25; p = 0.028). CVA was associated with lower HDL-C and longer duration of diabetes in younger/poor glycemic control group. Results by stepwise analysis were similar. Next, patients were divided into four groups based on gender and diabetic control(hemoglobinA1C < or > 7.0%). Multiple regression analysis revealed that IHD was associated with high systolic blood pressure in male/fair glycemic control group, age in male/poor control group, and short duration of diabetic history in females in both glycemic control groups. Interestingly, insulin use was associated with IHD in the male/poor group(OR = 4.11, 95% CI = 1.22-8.12; p = 0.018) and with CVA in the female/poor group(OR = 3.26, 95% CI = 1.12-6.24; p = 0.02). CVA was associated with short duration of diabetes in both female groups.</p> <p>Conclusions</p> <p>IHD and CVA risks are affected by specific factors in diabetics, such as treatment, gender and age. Specifically, insulin use has a potential role in preventing IHD but may also be a risk factor for CVA among the diabetic elderly, thus revealing a need to develop improved treatment strategies for diabetes in elderly patients. The Japan Cholesterol and Diabetes Mellitus Study was formulated to evaluate them(Umin Clinical Trials Registry, clinical trial reg. no. UMIN00000516; <url>http://www.umin.ac.jp/ctr/index.htm</url>).</p

DDB Accumulates at DNA Damage Sites Immediately after UV Irradiation and Directly Stimulates Nucleotide Excision Repair

Damaged DNA-binding protein, DDB, is a heterodimer of p127 and p48 with a high specificity for binding to several types of DNA damage. Mutations in the p48 gene that cause the loss of DDB activity were found in a subset of xeroderma pigmentosum complementation group E (XP-E) patients and have linked to the deficiency in global genomic repair of cyclobutane pyrimidine dimers (CPDs) in these cells. Here we show that with a highly defined system of purified repair factors, DDB can greatly stimulate the excision reaction reconstituted with XPA, RPA, XPC.HR23B, TFIIH, XPF.ERCC1 and XPG, up to 17-fold for CPDs and approximately 2-fold for (6-4) photoproducts (6-4PPs), indicating that no additional factor is required for the stimulation by DDB. Transfection of the p48 cDNA into an SV40-transformed human cell line, WI38VA13, was found to enhance DDB activity and the in vivo removal of CPDs and 6-4PPs. Furthermore, the combined technique of recently developed micropore UV irradiation and immunostaining revealed that p48 (probably in the form of DDB heterodimer) accumulates at locally damaged DNA sites immediately after UV irradiation, and this accumulation is also observed in XP-A and XP-C cells expressing exogenous p48. These results suggest that DDB can rapidly translocate to the damaged DNA sites independent of functional XPA and XPC proteins and directly enhance the excision reaction by core repair factors