42 research outputs found
Exploring the Stereostructural Requirements of Peptide Ligands for the Melanocortin Receptors
No full textNovel Cyclic Templates of alpha-MSH Give Highly Selective and Potent Antagonists/Agonists for Human Melanocortin-3/4 Receptors
No full textA New Method for Rapidly Generating Inhibitors of Glyoxalase I inside Tumor Cells Using S
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Glutathionyl Transferase Catalyzed Addition of Glutathione to COMC: A New Hypothesis for Antitumor Activity
No full textEffect of human leukocyte antigen-C and -DQ matching on pediatric heart transplant graft survival
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Natural Kinds, Similarity, and Individual Cases: Ontological Presuppositions and Ethical Implications
No full textThe ethical implications of medical research and clinical practice are addressed by (a) questioning the ontological presuppositions of such notions as kinds and similarity, both object-to-object and object-to-category; (b) applying this strategy to the particular case of medicine and biomedical science, with a focus on the notion of kinds of patients; and (c) suggesting a way for researchers and clinicians to take advantage of the ontological perspective, connecting creative approaches to responsible, ethical choices
Effects of Macrocycle Size and Rigidity on Melanocortin Receptor-1 and -5 Selectivity in Cyclic Lactam alpha-Melanocyte-Stimulating Hormone Analogs
No full textDuration of inotropic support after left ventricular assist device implantation: Risk factors and impact on outcome
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