Evaluation of automatic hypernym extraction from technical corpora in English and Dutch

In this research, we evaluate different approaches for the automatic extraction of hypernym relations from English and Dutch technical text. The detected hypernym relations should enable us to semantically structure automatically obtained term lists from domain- and user-specific data. We investigated three different hypernymy extraction approaches for Dutch and English: a lexico-syntactic pattern-based approach, a distributional model and a morpho-syntactic method. To test the performance of the different approaches on domain-specific data, we collected and manually annotated English and Dutch data from two technical domains, viz. the dredging and financial domain. The experimental results show that especially the morpho-syntactic approach obtains good results for automatic hypernym extraction from technical and domain-specific texts

Noise or music? Investigating the usefulness of normalisation for robust sentiment analysis on social media data

In the past decade, sentiment analysis research has thrived, especially on social media. While this data genre is suitable to extract opinions and sentiment, it is known to be noisy. Complex normalisation methods have been developed to transform noisy text into its standard form, but their effect on tasks like sentiment analysis remains underinvestigated. Sentiment analysis approaches mostly include spell checking or rule-based normalisation as preprocess- ing and rarely investigate its impact on the task performance. We present an optimised sentiment classifier and investigate to what extent its performance can be enhanced by integrating SMT-based normalisation as preprocessing. Experiments on a test set comprising a variety of user-generated content genres revealed that normalisation improves sentiment classification performance on tweets and blog posts, showing the model’s ability to generalise to other data genres

LeTs Preprocess: The multilingual LT3 linguistic preprocessing toolkit

This paper presents the LeTs Preprocess Toolkit, a suite of robust high-performance preprocessing modules including Part-of-Speech Taggers, Lemmatizers and Named Entity Recognizers. The currently supported languages are Dutch, English, French and German. We give a detailed description of the architecture of the LeTs Preprocess pipeline and describe the data and methods used to train each component. Ten-fold cross-validation results are also presented. To assess the performance of each module on different domains, we collected real-world textual data from companies covering various domains (a.o. automotive, dredging and human resources) for all four supported languages. For this multi-domain corpus, a manually verified gold standard was created for each of the three preprocessing steps. We present the performance of our preprocessing components on this corpus and compare it to the performance of other existing tools. 1

Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures

SARS-CoV-2 is the causative of the COVID-19 disease, which has spread pandemically around the globe within a few months. It is therefore necessary to collect fundamental information about the disease, its epidemiology and treatment, as well as about the virus itself. While the virus has been identified rapidly, detailed ultrastructural analysis of virus cell biology and architecture is still in its infancy. We therefore studied the virus morphology and morphometry of SARS-CoV-2 in comparison to SARS-CoV as it appears in Vero cell cultures by using conventional thin section electron microscopy and electron tomography. Both virus isolates, SARS-CoV Frankfurt 1 and SARS-CoV-2 Italy-INMI1, were virtually identical at the ultrastructural level and revealed a very similar particle size distribution with a median of about 100 nm without spikes. Maximal spike length of both viruses was 23 nm. The number of spikes per virus particle was about 30% higher in the SARS-CoV than in the SARS-CoV-2 isolate. This result complements a previous qualitative finding, which was related to a lower productivity of SARS-CoV-2 in cell culture in comparison to SARS-CoV.Peer Reviewe

The effects of lithium on reticulo-rumen motility of sheep and goats

Lithium salts are used experimentally to induce food aversions and as a marker for measuring the intake of supplements (Ralphs, 1992)

Terminologie: op het snijvlak van ambacht en technologie

Het artikel geeft een overzicht van de activiteiten en projecten binnen het vakgebied van de terminologie in de vakgroep VTC en zijn voorgangers. Zowel terminografische projecten als taaltechnologische toepassingen en termextractie komen aan bod

Detection of Toxoplasma gondii-specific antibodies in pigs using an oral fluid-based commercial ELISA: Advantages and limitations

Toxoplasma gondii is a major food-borne parasite and undercooked meat of infected pigs represents an important source of infection for humans. Since infections in pigs are mostly subclinical, adequate diagnostic tests for use at the farm level are pursued. Oral fluid (OF) was shown to be a promising matrix for direct and indirect detection of infections with various pathogens in pigs. The objective of this study was to assess whether T. gondii infections in pigs could be diagnosed using an indirect ELISA kit adapted for OF samples (OF-ELISA). Routine serology and OF-immunoblot (IB) were used as standards for the comparison. For this, serial OF samples from sows (n = 8) and fatteners (n = 3) experimentally inoculated with T. gondii oocysts, individual field samples from potentially exposed sows (n = 9) and pooled OF samples from potentially exposed group-housed fatteners (n = 195 pig groups, including 2,248 animals) were analysed for antibodies against T. gondii by ELISA. For individual animals, OF-ELISA exhibited a relative diagnostic specificity of 97.3% and a relative diagnostic sensitivity of 78.8%. In experimentally infected animals, positive OF-ELISA results were observed from 1.5 weeks post inoculation (pi) until the end of the experimental setup (8 to 30 weeks pi); however, values below the estimated cut-off were occasionally observed in some animals despite constant seropositivity. In potentially exposed individual animals, OF- and serum-ELISA results showed 100% agreement. In group-housed fatteners, antibodies against T. gondii could be reliably detected by OF-ELISA in groups in which at least 25% of the animals were seropositive. This OF-ELISA, based on a commercially available serum-ELISA, may represent an interesting non-invasive screening tool for detecting pig groups with a high exposure to T. gondii at the farm level. The OF-ELISA may need further adjustments to consistently detect individual infected pigs, probably due to variations in OF antibody concentration over time

Detection of Toxoplasma gondii-specific antibodies in pigs using an oral fluid-based commercial ELISA: advantages and limitations.

Toxoplasma gondii is a major food-borne parasite and undercooked meat of infected pigs represents an important source of infection for humans. Since infections in pigs are mostly subclinical, adequate diagnostic tests for use at the farm level are pursued. Oral fluid (OF) was shown to be a promising matrix for direct and indirect detection of infections with various pathogens in pigs. The objective of this study was to assess whether T. gondii infections in pigs could be diagnosed using an indirect ELISA kit adapted for OF samples (OF-ELISA). Routine serology and OF-immunoblot (IB) were used as standards for the comparison. For this, serial OF samples from sows (n = 8) and fatteners (n = 3) experimentally inoculated with T. gondii oocysts, individual field samples from potentially exposed sows (n = 9) and pooled OF samples from potentially exposed group-housed fatteners (n = 195 pig groups, including 2,248 animals) were analysed for antibodies against T. gondii by ELISA. For individual animals, OF-ELISA exhibited a relative diagnostic specificity of 97.3% and a relative diagnostic sensitivity of 78.8%. In experimentally infected animals, positive OF-ELISA results were observed from 1.5 weeks post inoculation (pi) until the end of the experimental setup (8 to 30 weeks pi); however, values below the estimated cut-off were occasionally observed in some animals despite constant seropositivity. In potentially exposed individual animals, OF- and serum-ELISA results showed 100% agreement. In group-housed fatteners, antibodies against T. gondii could be reliably detected by OF-ELISA in groups in which at least 25% of the animals were seropositive. This OF-ELISA, based on a commercially available serum-ELISA, may represent an interesting non-invasive screening tool for detecting pig groups with a high exposure to T. gondii at the farm level. The OF-ELISA may need further adjustments to consistently detect individual infected pigs, probably due to variations in OF antibody concentration over time

Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Diet-Induced Metabolic Syndrome in Rats

The signs of metabolic syndrome following chronic excessive macronutrient intake include body weight gain, excess visceral adipose deposition, hyperglycaemia, glucose and insulin intolerances, hypertension, dyslipidaemia, endothelial damage, cardiovascular hypertrophy, inflammation, ventricular contractile dysfunction, fibrosis, and fatty liver disease. Recent studies show increased activity of soluble epoxide hydrolase (sEH) during obesity and metabolic dysfunction. We have tested whether sEH inhibition has therapeutic potential in a rat model of diet-induced metabolic syndrome. In these high-carbohydrate, high-fat-fed rats, chronic oral treatment with trans-4-[4-(3-adamantan-1-ylureido)-cyclohexyloxy]-benzoic acid (t-AUCB), a potent sEH inhibitor, alleviated the signs of metabolic syndrome in vivo including glucose, insulin, and lipid abnormalities, changes in pancreatic structure, increased systolic blood pressure, cardiovascular structural and functional abnormalities, and structural and functional changes in the liver. The present study describes the pharmacological responses to this selective sEH inhibitor in rats with the signs of diet-induced metabolic syndrome